Results 281 to 290 of about 8,713,756 (356)

Early CD4+ T cell proliferation and chronic T cell engagement impact myeloma outcomes following T cell engager therapy. [PDF]

J Clin Invest
Duffy AM, Goenka A, Azeem MI, Taz A, Potdar SV, Scott SA, Marin E, Kaufman JL, Hofmeister CC, Joseph NS, Gupta VA, Lonial S, Nooka AK, Dhodapkar MV, Dhodapkar KM.   +14 more
europepmc   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Regulatory T cell approaches for graft-versus-host disease prevention. [PDF]

Curr Opin Immunol
Bader CS, Meyer EH, Negrin RS.
europepmc   +1 more source

Editorial: Enhancing CAR T-cell therapy with imaging. [PDF]

Front Immunol
Lopci E, de Jong D, Dercle L.
europepmc   +1 more source

CD3 aptamers promote expansion and persistence of tumor-reactive T cells for adoptive T cell therapy in cancer

Ashwathi Puravankara Menon, Helena Villanueva, Daniel Meraviglia-Crivelli, Hisse M. van Santen, Joschka Hellmeier, Angelina Zheleva, Francesca Nonateli, Timo Peters, Tassilo L A Wachsmann, Mercedes Hernández-Rueda, Johannes B Huppa, Gerhard J Schütz, Eva Sevcsik, Beatriz Moreno, Fernando Pastor   +14 more
openalex   +1 more source

Acquisition of an immunosuppressive microenvironment after anti-CD19 CAR T-cell therapy is associated with T-cell dysfunction and resistance. [PDF]

J Immunother Cancer
Ponzo M, Drufuca L, Buracchi C, Sindoni MM, Nucera S, Bugarin C, Bason R, Rossetti G, Bonnal R, Meli C, Rambaldi B, Lussana F, Ferrari S, Moretti A, Dastoli G, Risca G, Pellegrino C, Manz MG, Galimberti S, Rambaldi A, Gaipa G, Biondi A, Pagani M, Magnani CF.   +23 more
europepmc   +1 more source

Proteasome: Role in T Cell Function Regulation. [PDF]

Int J Biol Sci
Tang D, Wu X, Lei JH, Qiao Y, Deng CX.
europepmc   +1 more source