Results 251 to 260 of about 1,940,376 (313)

Ex vivo and in vivo CRISPR/Cas9 screenings identify the roles of protein N-glycosylation in regulating T-cell activation and functions. [PDF]

Elife
Hong Y, Si X, Liu W, Mai X, Zhang Y.
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Optimization of THP-1-CAR monocytes utilizing CD32a signaling phagocytosis for antigen-specific T cell activation. [PDF]

Sci Rep
Hong J, Lee S, Kim Y, Kang CK, Park WB, Shin HM, Kim HR, Lee CH.   +7 more
europepmc   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Regulatory-like FOXP3+Helios+CD4+ T conventional cells correlate with T-cell activation after Orca-T immunotherapy.

Blood
Bader CS, Killian S, Iliopoulou BP, Chen PI, Pathak S, Le CT, Villar-Prados A, Ji X, Jensen KP, Negrin RS, Meyer EH.   +10 more
europepmc   +1 more source

HLA-DR+ CD8+ T lymphocytes as an alternative T-cell activation marker in pediatric HLH: A real-life study. [PDF]

Pediatr Allergy Immunol
Triaille C, Fernandez I, Touzot F.
europepmc   +1 more source

Co-localization of lymph node therapeutics enhances T cell activation and anti-tumor response. [PDF]

Biomaterials
Shen R, Kapnick SM, Edwards C, McIlvaine RA, Bridgeman CJ, Carey ST, Jewell CM.   +6 more
europepmc   +1 more source

Oligodendrocyte transcription factor 2 orchestrates glioblastoma immune evasion by suppressing CXCL10 and CD8+ T cell activation. [PDF]

J Clin Invest
Zhang X, Xue J, Zhao C, Zeng C, Zhong J, Yu G, Yang X, Ling Y, Li D, Yang J, Xiu Y, Li H, Hong S, Qiao L, Chen S, Lu QR, Deng Y, Tang Z, Lu F.   +18 more
europepmc   +1 more source

Cytochrome c oxidase dependent respiration is essential for T cell activation, proliferation and memory formation. [PDF]

Nat Commun
Tarasenko TN, Warren E, Singh B, Fuchs A, Marin J, Szibor M, King C, McGuire PJ.   +7 more
europepmc   +1 more source

Microwave ablation combined with dendritic cells enhances CD8⁺ T cell activation in rechallenged tumor mouse model. [PDF]

Cancer Immunol Immunother
Ma J, Xu F, Wang M, Zhang S, Sang J, Chen H, Wen F, Ge R, Xie Q, Wei Z, Ye X.   +10 more
europepmc   +1 more source