Results 221 to 230 of about 2,637,595 (353)

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Benchmarking of T cell receptor-epitope predictors with ePytope-TCR. [PDF]

Cell Genom
Drost F, Chernysheva A, Albahah M, Kocher K, Schober K, Schubert B.   +5 more
europepmc   +1 more source

Germline sequence of two human T-cell receptor Vβ genes: Vβ8.1 is transcribed from a TATA-box promoter

, 1987
Wendy Smith, Alan Tunnacliffe, Terence H. Rabbitts   +2 more
openalex   +2 more sources

Functional isotypes are not encoded by the constant region genes of the beta subunit of the T cell receptor for antigen/major histocompatibility complex. [PDF]

, 1984
H D Royer, Armand Bensussan, Oreste Acuto, Ellis L. Reinherz   +3 more
openalex   +1 more source

Tumor‐agnostic detection of circulating tumor DNA in patients with advanced pancreatic cancer using targeted DNA methylation sequencing and cell‐free DNA fragmentomics

Molecular Oncology, EarlyView.
We evaluated circulating tumor DNA (ctDNA) detection in advanced pancreatic cancer using DNA methylation, cell‐free DNA fragment lengths, and 5′ end motifs. Machine learning models were trained to estimate ctDNA levels from each feature and their combination.
Morten Lapin, Kjersti Tjensvoll, Karin Hestnes Edland, Satu Oltedal, Herish Garresori, Bjørnar Gilje, Saga Ekedal, Trygve Eftestøl, Jan Terje Kvaløy, Filip Janku, Oddmund Nordgård   +10 more
wiley   +1 more source

Editorial: New avenues for the development of advanced immunotherapies: capitalizing on studies of the B and T cell receptor repertoire. [PDF]

Front Immunol
Nicolini F, Naranjo Gomez M, Pelegrin M, De Lucia A, Mazzotti L, Mazza M.   +5 more
europepmc   +1 more source

The V gamma locus of the human T cell receptor gamma gene. Repertoire polymorphism of the first variable gene segment subgroup. [PDF]

, 1988
M P Font, Z Chen, Jean Christophe Bories, N Duparc, Philippe M. Loiseau, L Degos, Howard M. Cann, Daniel Cohen, J Dausset, F Sigaux   +9 more
openalex   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Machine learning reveals distinct T-cell receptor clusters in plasma cell dyscrasias compared to healthy controls. [PDF]

PLoS One
Coffey DG, Zhang Y, Hill E, Cross F, Philip R, Theoret MR, Landgren O, Baines AC, Kazandjian D.   +8 more
europepmc   +1 more source

Phorbol esters and calcium ionophores differentially regulate the transcription of gamma-T-cell antigen receptor gene in human thymocytes.

, 1988
Héctor Martínez-Valdez, Ellen Thompson, Amos Cohen   +2 more
openalex   +1 more source