Results 261 to 270 of about 1,770,050 (315)
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The American Journal of Medicine, 1988
Over the past few decades, a solid body of evidence has been built up linking certain autoimmune diseases to the presence of specific major histocompatibility complex haplotypes. Major histocompatibility complex products are used by the immune system to distinguish non-self from self and are important in the recognition of foreign antigen by T cells. T
N, Caccia, T W, Mak
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Over the past few decades, a solid body of evidence has been built up linking certain autoimmune diseases to the presence of specific major histocompatibility complex haplotypes. Major histocompatibility complex products are used by the immune system to distinguish non-self from self and are important in the recognition of foreign antigen by T cells. T
N, Caccia, T W, Mak
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2008
The T-cell antigen receptor complex (TCR/CD3) is a cell surface structure that defines the T lymphocyte lineage, where it fulfills two basic functions, namely antigen recognition and triggering of signals needed to mount adequate responses to foreign aggression and/or to undergo differentiation.
Jose M, Rojo +2 more
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The T-cell antigen receptor complex (TCR/CD3) is a cell surface structure that defines the T lymphocyte lineage, where it fulfills two basic functions, namely antigen recognition and triggering of signals needed to mount adequate responses to foreign aggression and/or to undergo differentiation.
Jose M, Rojo +2 more
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T cells with receptors for IgD
Nature, 1985The role of IgD in the immune response has been elusive, although its predominance on the cell surface suggests a receptor function. We have shown previously that euthymic but not athymic BALB/c mice, injected with IgD before antigen, exhibit enhanced antibody responses which can be transferred by T cells. Isotype-specific T cells have been reported to
R F, Coico +5 more
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Dermatologic Clinics, 1990
We have reviewed the knowledge of the human TCR and its implications in dermatology. The TCR has been shown to be the molecule responsible for specific cellular immunity in the same way that immunoglobulins confer humoral immunity. Much has been learned about the complex genomic organization of the TCR chains and how the great diversity of TCR proteins
K, Degitz, S W, Caughman
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We have reviewed the knowledge of the human TCR and its implications in dermatology. The TCR has been shown to be the molecule responsible for specific cellular immunity in the same way that immunoglobulins confer humoral immunity. Much has been learned about the complex genomic organization of the TCR chains and how the great diversity of TCR proteins
K, Degitz, S W, Caughman
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T Cell Receptors and T Cell Development
1996Birds provide a valuable model system for the study of early development. Studies of immune system development and function in chickens have contributed to some of the central tenets in immunology. These include:(1) allorecognition by lymphocytes in graft-vs-host (GVH) reactions (Simonsen 1985), (2) clonal reactivity of immunocompetent lymphocytes ...
C H, Chen +6 more
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Cytotherapy, 2003
Artificial T-cell receptors are generated by joining an Ag-recognizing domain (ectodomain) to the transmembrane and intracellular portion of a signaling molecule (endodomain). The ectodomain is most often derived from Ab variable chains, but may also be generated from T-cell receptor variable chains, as well as from other molecules. Various alternative
M, Pule, H, Finney, A, Lawson
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Artificial T-cell receptors are generated by joining an Ag-recognizing domain (ectodomain) to the transmembrane and intracellular portion of a signaling molecule (endodomain). The ectodomain is most often derived from Ab variable chains, but may also be generated from T-cell receptor variable chains, as well as from other molecules. Various alternative
M, Pule, H, Finney, A, Lawson
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New England Journal of Medicine, 1985
During the past 25 years, we have gradually come to comprehend the underlying order of the complex family of lymphocytes.
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During the past 25 years, we have gradually come to comprehend the underlying order of the complex family of lymphocytes.
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T-Cell Receptor Expression in the T-Cell Malignancies
American Journal of Clinical Pathology, 1990Twenty-eight cases with T-cell neoplasms (10 with T-cell acute lymphoblastic leukemia [T-ALL], 10 with T-lymphoblastic lymphoma, and 8 with peripheral T-cell lymphomas) and 2 cases with reactive lymph nodes were immunohistochemically stained with monoclonal antibodies beta F1, delta TCS1, and WT31; beta F1 antibody recognizes the beta-subunit of T-cell
N, Mori +4 more
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Designer T cells by T cell receptor replacement
European Journal of Immunology, 2006AbstractT cell receptor (TCR) gene transfer is a convenient method to produce antigen‐specific T cells for adoptive therapy. However, the expression of two TCR in T cells could impair their function or cause unwanted effects by mixed TCR heterodimers. With five different TCR and four different T cells, either mouse or human, we show that some TCR are ...
Daniel, Sommermeyer +11 more
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JAMA: The Journal of the American Medical Association, 1988
A VERTEBRATE is an attractive culture medium for viruses, bacteria, fungi, and metazoan parasites. It is therefore understandable that vertebrates have had to develop a body defense mechanism directed toward these pathogens for their emergence and survival. This defense mechanism is the See also pp 1834 and 1837. immune system.
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A VERTEBRATE is an attractive culture medium for viruses, bacteria, fungi, and metazoan parasites. It is therefore understandable that vertebrates have had to develop a body defense mechanism directed toward these pathogens for their emergence and survival. This defense mechanism is the See also pp 1834 and 1837. immune system.
openaire +2 more sources