Results 251 to 260 of about 1,770,050 (315)

Dynamic Allostery in T Cell Receptor Specificity: A Role for Peptides and MHC Polymorphisms in Allosterically Tuning Immune Recognition. [PDF]

Bioessays
Eldaly B, Baker BM.
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Unique phenotypic and T cell receptor characteristics of CD8⁺ T cells accumulated in the brains of Alzheimer's disease mice. [PDF]

Sci Rep
Zhihuan W, Furusawa-Nishii E, Miyake S.
europepmc   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

A Biologically Informed Vision-Guided Framework for Interpretable T Cell Receptor-Epitope Binding Prediction. [PDF]

Adv Sci (Weinh)
Yuan Y, Chen J, Zhang Y, Fang Y, Fang Z, Chu Y, Li J, Zhang C, Li Y, Wei D.   +9 more
europepmc   +1 more source

Resolution of Squamous-Cell Carcinoma by Restoring T-Cell Receptor Signaling. [PDF]

N Engl J Med
Ye P, Bergerson JRE, Brownell I, Starrett GJ, Abraham RS, Anderson MV, Martin T, MacMath D, Kuehn HS, Padiadpu J, Zhao S, Rosenzweig SD, Tussiwand R, Leonard WJ, Pittaluga S, Raffeld M, Arnold DE, Lisco A.   +17 more
europepmc   +1 more source

Mechano-pharmacology of T cell receptor specificity. [PDF]

Cell Res
Fei P, Dustin ML.
europepmc   +1 more source

High-throughput profiling of the T cell receptor delta CDR3 repertoire reveals species-specific patterns in cattle (Bos taurus) and water buffalo (Bubalus bubalis). [PDF]

Front Immunol
Zhang Y, Wu F, Ma L, Yao X, Li J.
europepmc   +1 more source

T cell-microbiome associations captured through T cell receptor convergence analysis

Vandoren R, Ha M, Van Deuren V, De Roeck N, Pu T, Brand EC, Kuznetsova M, Besbassi H, Bartholomeus E, Affaticati F, De Boeck I, Gehrmann T, Lebeer S, Oldenburg B, van Wijk F, Delputte P, Verbandt S, Tejpar S, Laukens K, Ogunjimi B, Meysman P.   +20 more
europepmc   +1 more source

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The T Cell Receptor

Science, 1987
The primary structure of T cell receptor proteins and genes is well understood. Immunologists are now trying to understand the properties of these interesting molecules. Evidence suggests that T cell αβ receptors recognize a complex of an antigen-derived peptide bound to one of the cell-surface products of the major histocompatibility complex (MHC ...
P, Marrack, J W, Kappler
openaire   +3 more sources