Results 261 to 270 of about 118,951 (307)

Spatially resolved T cell receptor diversity mapping uncovers variability of the cancer immune microenvironment. [PDF]

EBioMedicine
Magoulopoulou A, Chatzinikolaou M, Metousis A, Hu T, Yu H, Zerdes I, Wang K, Foukakis T, Long M, Leandersson K, Micke P, Strell C, Nilsson M.   +12 more
europepmc   +1 more source

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

APOBEC2 deficiency disrupts hematopoietic lineage commitment, resulting in emergence of dual identity lymphocytes in mice and humans. [PDF]

Proc Natl Acad Sci U S A
Moris Amro E, Gkougkousis C, Seebass JG, Telioglu I, Bakr A, Lorenzo JP, Abolhassani H, Altenhofen J, Berntson L, Ruf S, Hammarström L, Pan-Hammarström Q, Imbusch CD, Papavasiliou FN.   +13 more
europepmc   +1 more source

Autoimmunity and Periodontitis

Journal of Periodontal Research, EarlyView.
In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga, Vivek Thumbigere‐Math, Mark C. Herzberg   +2 more
wiley   +1 more source

Periodontitis and Inflammatory Bowel Diseases: Mechanistic Evidence

Journal of Periodontal Research, EarlyView.
This review aims to provide a conceptual framework for understanding the mechanistic interplay between periodontitis and IBD, with a particular emphasis on the microbial and immunological crosstalk linking the oral cavity and the gastrointestinal tract.
Ana Paula V. Colombo, Adriana M. de Oliveira, Nobuhiko Kamada, Sho Kitamoto   +3 more
wiley   +1 more source

Targeting non-canonical antigens unlocks functional T-cell responses in renal cell carcinoma. [PDF]

J Immunother Cancer
Wang J, Zhu Y, He X, Yin S, He Y, Yao P, Li J, Li X, Shi P, Qian R, Xiao Z, Ye X, Xi JJ, Ye B.   +13 more
europepmc   +1 more source

Engagement of the TCR against an oncolytic virus generates a population of effector CAR T cells with potent antitumor activity. [PDF]

Sci Adv
Liseth O, Appleton E, Kendall B, Thompson J, Sangsuwannukul T, Tonne J, Diaz RM, Evgin L, Patrikeev A, Sarbia N, Foo S, Harrington K, Ono M, Melcher A, Vile R.   +14 more
europepmc   +1 more source

Immunological Interactions Between Gammadelta T Cells and West Nile Virus in the Infected Host. [PDF]

Rev Med Virol
Cimini E, Tartaglia E, Cristofanelli F, Gili S, Maggi F.   +4 more
europepmc   +1 more source

Ionizing Radiation Enhances Prognostically Significant Cellular Immunity Programs in the Brain Metastasis Microenvironment. [PDF]

Clin Cancer Res
Fukumura K, Jiang P, Yeboa DN, Singareeka Raghavendra A, Gubbiotti MA, Andersen CR, Ferguson SD, Duose DY, Kudo Y, Arun B, Reuben A, Huse JT, Ibrahim NK.   +12 more
europepmc   +1 more source

Central Nervous System T-cell immune architecture, and not HIV burden, tracks with cognition under long-term viral suppression. [PDF]

PLoS Pathog
Trunfio M, Caballero G, Gomez-Moreno V, Mallal SA, Wanjalla CN, Jones A, Beeri K, Wells A, LaMere S, Gouaux B, Franklin DR, Corley M, Ellis RJ, Moore DJ, Letendre SL, Smith D, Chaillon A, Gianella S.   +17 more
europepmc   +1 more source