Results 71 to 80 of about 56,239 (298)
Serial Analysis of the T-Cell Receptor β-Chain Repertoire in People Living With HIV Reveals Incomplete Recovery After Long-Term Antiretroviral Therapy
Frontiers in Immunology, 2022 Long-term antiretroviral therapy (ART) in people living with HIV (PLHIV) is associated with sustained increases in CD4+ T-cell count, but its effect on the peripheral blood T-cell repertoire has not been comprehensively evaluated.Andrea M. H. Towlerton, Shashidhar Ravishankar, David G. Coffey, David G. Coffey, David G. Coffey, Camille E. Puronen, Camille E. Puronen, Edus H. Warren, Edus H. Warren +8 moredoaj +1 more sourceAugmenting adaptive immunity: progress and challenges in the
quantitative engineering and analysis of adaptive immune receptor repertoires
, 2019 The adaptive immune system is a natural diagnostic and therapeutic. It
recognizes threats earlier than clinical symptoms manifest and neutralizes
antigen with exquisite specificity.Abbas, Adams, Adli, Alipanahi, Alpert, AlQuraishi, Altan-Bonnet, Angeletti, Angermueller, Antunes, Arora, Arora, Arora, Azizi, Ba, Bachmann, Bandeira, Baran, Barlow, Bashford-Rogers, Bashor, Bassani-Sternberg, Bassani-Sternberg, Bassani-Sternberg, Bassing, Baumgarth, Ben-Hamo, Benjamin, Benjamin, Bentzen, Bentzen, Bepler, Bethune, Bhat, Birnbaum, Biswas, Blythe, Bolotin, Bongartz, Boyd, Bradbury, Bradley, Breden, Brenner, Briggs, Briney, Britanova, Broere, Brown, Buenrostro, Bulik-Sullivan, Burnett, Busse, Cao, Carey, Carmona, Carreno, Casadevall, Casini, Chaudhary, Chen, Cheow, Cheung, Chevalier, Ching, Christina Fan, Cinelli, Cobey, Cohen, Cohen, Cole, Corcoran, Correia, Corrie, Croote, Cybenko, Daberdaku, Dash, Davies, Davis, Davis, Davis, De Neuter, Deac, DeKosky, DeKosky, Devilder, Devulapally, DeWitt, DeWitt 3rd, DeWitt III, Dey, Ecker, Egorov, Egorov, EL-Manzalawy, EL-Manzalawy, EL-Manzalawy, Elgundi, Elhanati, Elhanati, Elhanati, Elhanati, Elton, Emerson, Emini, Esteva, Eyer, Farlik, Farmer, Farmer, Fellouse, Ferdous, Fine, Fink, Fischer, Fischman, Fishman, Flower, Fowler, Frank, Friedensohn, Galperin, Galson, Gee, Gee, Geering, Gentiluomo, Georgiev, Georgiou, Gidoni, Gielis, Glanville, Glanville, Goddard, Goldstein, Goodfellow, Goodfellow, Gowthaman, Graf, Greaves, Greenbaum, Greenspan, Greenspan, Greenspan, Greiff, Greiff, Greiff, Greiff, Greiff, Griffiths, Grigaityte, Guo, Guo, Hadrup, Halperin, Han, Han, Hartweger, Hashimshony, Hashimshony, Haynes, He, Heather, Heather, Hebditch, Heemskerk, Hellman, Hillman, Hochgerner, Hochreiter, Hochreiter, Hoehn, Hoehn, Holder, Holland, Holzinger, Hoogenboom, Hopp, Hornik, Hou, Howie, Hua, Huang, Imkeller, Irvine, Ishino, Islam, Islam, Jackson, Jackson, Jacobs, Jacobsen, Jacobsen, Jain, Jain, Jaitin, Janin, Jardine, Jardine, Jeanbart, Jerne, Jespersen, Joglekar, Jokinen, June, Jyothi, Kabat, Kanyavuz, Kaplon, Karplus, Keich, Keskin, Khosravi-Maharlooei, Kieke, Kingma, Kisielow, Klambauer, Klebanoff, Konishi, Korn, Kotzias, Kovaltsuk, Kramer, Krawczyk, Krawczyk, Krawczyk, Kringelum, Kunik, Kunik, Kuroda, Lanchantin, Lanzarotti, Lapidoth, Lapidoth, Laplane, Larsen, Lauer, Lavinder, Lavoie, LeCun, Lee, Lee, Legutki, Legutki, Levitt, Li, Li, Li, Li, Liberis, Lindeman, Linette, Liu, Liu, Liu, Liu, Lollier, Longo, Lu, Luo, Luo, Luo, López-Santibáñez-Jácome, Løset, MacBeath, Macosko, Madi, Madi, Mahajan, Manavalan, Manczinger, Mangul, Mangul, Marchalonis, Marcou, Margalit, Marrack, Marrack, Marrack, Martin, Martin, Mascola, Mason, Mason, Mayer, McDaniel, Meng, Merbl, Meysman, Mian, Migalska, Miho, Miho, Minhas, Moffett, Mohan, Mora, Mora, Murphy, Murugan, Muyldermans, Navalkar, Nemazee, Newell, Newell, Newell, Nimrod, North, Oakes, Ohlin, Olson, Ostmeyer, Ostmeyer, Ott, Ott, Padlan, Palme, Parker, Parola, Patterson, Pellequer, Perelson, Perelson, Persson, Peterson, Picelli, Pierce, Pittala, Pogorelyy, Pogorelyy, Pogson, Ponomarenko, Ponomarenko, Pou, Preuer, Priel, Purwada, Purwada, Quang, Radbruch, Ramos-López, Ramsköld, Raybould, Remington, Reshetova, Ribeiro, Richards, Richman, Riley, Rives, Rizzetto, Robert, Robins, Robins, Robinson, Rosati, Rosenberg, Rosenblatt, Rubelt, Rubinstein, Sahin, Saikia, Sandve, Sandve, Sblattero, Schmitt, Schneider, Schneider-Hohendorf, Schroeder, Schumacher, Schwab, Scott, Seet, Segler, Seimetz, Sela-Culang, Sela-Culang, Sela-Culang, Sethna, Sethna, Setliff, Sette, Sewell, Shah, Shalev-Shwartz, Sharon, Shaw, Shokri, Shugay, Shugay, Sidhom, Sidhom, Sikorski, Simonovsky, Simonyan, Sircar, Sircar, Slocombe, Smallwood, Soto, Spiess, Stoeckius, Stone, Strauli, Stubbington, Stubbington, Sundararajan, Swartz, Sylwester, Szegedy, Tague, Talmage, Tang, Taussig, Thakkar, Thomas, Thomas, Tickotsky, Tiller, Tirosh, Tompa, Tonegawa, Townsend, Trepel, Trolle, Turchaninova, Turner, Udyavar, Vamathevan, van der Schoot, Van Regenmortel, Venturi, Verkoczy, Vollmers, Voss, Vázquez Bernat, Wainberg, Walsh, Wang, Wang, Wang, Wang, Wang, Wang, Wang, Wardemann, Wardemann, Wardemann, Watson, Weinstein, Weitzner, Weitzner, Whitehead, Williams, Wine, Wine, Wirth, Woese, Wucherpfennig, Wurch, Xu, Xu, Xu, Yaari, Yaari, Yager, Yang, Younger, Zandian, Zarnitsyna, Zhang, Zhang, Zhao, Zhao, Zhao, Zheng, Zirlik, Zong +478 morecore +1 more sourceBiomimetic Nanovaccine Integrating Dendritic Cell Exosomes with Tumor Cell Membranes for Sustained Prophylaxis Against Glioblastoma
Advanced Functional Materials, EarlyView.We have developed DEX/GM, an all‐natural, personalizable hybrid vaccine designed by coating dendritic cell‐derived exosomes (DEX) onto tumor cell membranes (GM) for sustained prophylaxis against glioblastoma (GBM). ABSTRACT
Glioblastoma (GBM), one of the most aggressive and lethal brain tumors, remains incurable with a poor clinical prognosis.Shanshan Li, Dongya Zhang, Shiyu Wang, Changhe Pang, Meng Zheng, Bingyang Shi, Yan Zou +6 morewiley +1 more sourceStable global repertoire architecture masks short-term clonal remodeling in intratumoral TCR repertoires
Frontiers in ImmunologyBackgroundTumor-infiltrating T cell receptor repertoires are increasingly profiled to assess intratumoral T cell dynamics and inform prognosis and treatment response.Pernille G. Pedersen, Odd L. Gammelgaard, Sofie Traynor, Christina H. Ruhlmann, Christina H. Ruhlmann, Aida S. Hansen, Henrik J. Ditzel, Henrik J. Ditzel, Henrik J. Ditzel, Morten F. Gjerstorff, Mikkel G. Terp +10 moredoaj +1 more sourceCovert repertoires: ecotage in the UK [PDF]
, 2004 Ecological sabotage (ecotage) has been a feature of the more radical parts of the environmental movement in the Western world for several decades. While it may be perceived as being the preserve of underground cells of 'eco-terrorists', in the UK those ...Doherty, BJA, Plows, A, Wall, Dcore +2 more sourcesEnhanced Human Antigen‐Specific B Cell Responses Using In Vitro 3D Tonsil Cultures Containing Stromal Cells
Advanced Healthcare Materials, EarlyView.We developed a fully human 3D tonsil cell culture system incorporating supportive stromal cells that better sustains and activates immune cells than conventional methods. The model generates stronger, more targeted antibody responses to viral antigens and vaccines, providing a physiologically relevant and entirely human platform for studying immune ...Maaike V. J. Braham, Marlon de Gast, Liubov Babii, Sabine Kruijer, Theo M. Bestebroer, Mathilde Richard, Mathieu Claireaux, S. Marieke van Ham, Jelle de Wit, Cécile A. C. M. van Els, Anja ten Brinke, Marit J. van Gils +11 morewiley +1 more sourceγδ T cell responses: How many ligands will it take till we know? [PDF]
, 2018 γδ T cells constitute a sizeable and non-redundant fraction of the total T cell pool in all jawed vertebrates, but in contrast to conventional αβ T cells they are not restricted by classical MHC molecules.Adams, Adams, Allison, Allison, Ariadni Kouzeli, Aydintug, Aydintug, Bai, Barbee, Benyamine, Blumerman, Bonneville, Bonneville, Born, Born, Born, Bruder, Cai, Cairo, Castella, Cendron, Champagne, Chen, Chien, Chien, Chodaczek, Clark, Couzi, Crowley, Dai, Dalessandri, Davey, Davey, David Vermijlen, Davies, de Bruin, Deborah Gatti, Di Marco Barros, Dieudé, Dimova, Dornmair, Déchanet, Eberl, F. Ramírez-Valle, Fahl, Fisher, Fournié, Fu, Fujikado, Gelderblom, Gertner-Dardenne, Gober, Godfrey, Gras, Gu, Haas, Halary, Harden, Harly, Hartwig, Hayes, Heilig, Hein, Hirano, Holderness, Hsiao, Huang, Itohara, Jensen, Jin, Kaminski, Karunakaran, Karunakaran, Kashani, Kazen, Keyes, Komori, Laggner, Lalor, Lebrero-Fernández, Lefranc, Li, Li, Lin, Linguiti, Liuzzi, Liuzzi, Luoma, Maeda, Mangan, Marlin, Martin, Matis, Matthias Eberl, McCarthy, McGill, Miles, Misiak, Mookerjee-Basu, Morita, Morita, Murphy, Muñoz-Ruiz, Muñoz-Ruiz, O'Brien, Parker, Pellicci, Pitard, Prinz, Ramírez-Valle, Ravens, Rhodes, Rhodes, Rhodes, Riaño, Ribeiro, Riganti, Roberts, Rovito, Roy, Russano, Russano, Rust, Salim, Sandstrom, Schild, Sciammas, Sebestyen, Seo, Sewell, Shen, Sheridan, Sherwood, Sicard, Silva-Santos, Silva-Santos, Simone, Singh, Spada, Spencer, St Leger, Sutton, Teja Rus, Telfer, Thompson, Tonegawa, Tyler, Uldrich, Van hede, Van Rhijn, Vantourout, Vavassori, Vermijlen, Vermijlen, Vidović, Wan, Wei, Wencker, Willcox, Wu, Wucherpfennig, Xia, Xiong, Xu, Zeng, Zeng, Zocchi +166 morecore +1 more sourceMapping the Cerebral Organoid Landscape: A Systematic Review of Preclinical 3D Models in Neuroscience
Advanced Healthcare Materials, EarlyView.Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...Anna Wolfram, Vanessa Arnold, Maik Wolfram‐Schauerte, Anastassiya Moskalchuk, Caroline Trust, Marie Vontz, Mona Scheurenbrand, Vijayasarathy Sampath‐Kumar, Sogand Ahari, Carlos Romero‐Nieto, Lisa Sevenich +10 morewiley +1 more sourceImmunogenetic Profiling for Gastric Cancers Identifies Sulfated Glycosaminoglycans as Major and Functional B Cell Antigens in Human Malignancies
Cell Reports, 2017 Summary: Recent successes in tumor immunotherapies have highlighted the importance of tumor immunity. However, most of the work conducted to date has been on T cell immunity, while the role of B cell immunity in cancer remains more elusive. In this study,Hiroto Katoh, Daisuke Komura, Hiroki Konishi, Ryohei Suzuki, Asami Yamamoto, Miwako Kakiuchi, Reiko Sato, Tetsuo Ushiku, Shogo Yamamoto, Kenji Tatsuno, Takashi Oshima, Sachiyo Nomura, Yasuyuki Seto, Masashi Fukayama, Hiroyuki Aburatani, Shumpei Ishikawa +15 moredoaj +1 more source
