Results 141 to 150 of about 41,042,307 (363)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Central nervous system (CNS) relapse of neuroblastoma carries a poor prognosis, and craniospinal irradiation (CSI) poses substantial long‐term toxicity in young children. We report a toddler with MYCN‐amplified neuroblastoma harboring somatic ALK R1275Q who developed extensive leptomeningeal relapse with paraplegia.
Jinwoo Kim +11 more
wiley +1 more source
Open MedicineThis study aimed to investigate the potential causal relationship between immune cell and the risk of ulcerative colitis (UC), and to explore whether serum metabolites may mediate this association, thereby suggesting potential biomarkers or therapeutic ...
Chen Li, Yi Ying, Zhu Yun
doaj +1 more source
Role of regulatory T cells in immune tolerance [PDF]
, 2009 In this present work, we investigated the role of dendritic cells (DC) and regulatory T cells (Treg) in immune tolerance as well as their potential in the treatment of autoimmune or graft versus host (GvH) diseases.
Swee, Lee Kim
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Heavy menstrual bleeding (HMB) is a common condition among adolescents and young adults (AYAs) and is the leading cause of iron deficiency anemia (IDA) in this population. Growing evidence suggests that social determinants of health (SDOH) influence menstrual bleeding patterns, access to care, and treatment. However, no studies have
Maria Carter‐Febres +6 more
wiley +1 more source
OncoImmunology, 2018 Vitamin D deficiency is frequently observed in human cancer patients and a prognostic relevance could be shown for some entities. Additionally, it is known that vitamin D can stimulate the patients’ antitumor immunity. However, valid epidemiological data
Florian Bochen +14 more
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng +3 more
wiley +1 more source
Interferon-Driven Immune Dysregulation in Down Syndrome: A Review of the Evidence
Journal of Inflammation Research, 2021 Howard Chung,1,2 Peter HR Green,1,3 Timothy C Wang,1 Xiao-Fei Kong1,3 1Division of Digestive and Liver Diseases, Department of Medicine, Columbia University Irving Medical Center, New York, NY, 10032, USA; 2Department of Internal Medicine, Icahn School ...
Chung H, Green PH, Wang TC, Kong XF
doaj
Regulatory T Cells: Mechanisms of Differentiation and Function
Annual Review of Immunology, 2012 The immune system has evolved to mount an effective defense against pathogens and to minimize deleterious immune-mediated inflammation caused by commensal microorganisms, immune responses against self and environmental antigens, and metabolic ...
Steven Z. Josefowicz +2 more
semanticscholar +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Instruction Tenapanor potentially affects fluid volume and blood pressure. This study explored its effects on these parameters in patients undergoing peritoneal dialysis (PD). Methods We conducted a single‐arm, prospective observational study that enrolled 10 patients on PD with hyperphosphatemia who were newly initiated on tenapanor.
Shun Yoshida +11 more
wiley +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source