Results 161 to 170 of about 3,681,633 (268)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Metadomain and metaloop genome interactions in mammalian T cells. [PDF]

Cell Rep
Dolsten G, Wang ZM, Huang X, Song S, Wilson MJ, Bing XY, Ke W, Cafiero TR, Nelson AN, Fernando S, Ploss A, Schedl P, Levine MS, Viny AD, Rudensky AY, Pritykin Y.   +15 more
europepmc   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

LRRC15-CAR T Cells for the Treatment of Osteosarcoma. [PDF]

Clin Cancer Res
O'Reilly C, Tuladhar S, Nguyen P, Sheppard H, Koo SC, Chockley P, Houke H, Santiago T, Tian L, Jeschke J, Beckett AN, Chabot A, Yustein J, Krenciute G, Talbot LJ, Gottschalk S, DeRenzo C.   +16 more
europepmc   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

γδ T Cells in Autoinflammatory Diseases. [PDF]

Cells
Bank I.
europepmc   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Mixed Signals: T Cells as Architects of IgE Immunity. [PDF]

Immunol Rev
Tierney AL, Bezerra WP, Eisenbarth SC, Williams A.   +3 more
europepmc   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Multiparametric Characterization of Telomere Length in T Cells by Flow-FISH. [PDF]

Curr Protoc
Trigueros M, Kharraz Y, Alzayat H, Blanco J, Negredo E, Fernandez MA, Massanella M.   +6 more
europepmc   +1 more source