Results 181 to 190 of about 27,710,413 (387)

Subsets of exhausted CD8+ T cells differentially mediate tumor control and respond to checkpoint blockade

open access: yesNature Immunology, 2019
Brian C. Miller   +40 more
semanticscholar   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Kinetics of MHC-CD8 Interaction at the T Cell Membrane [PDF]

open access: bronze, 2007
Jun Huang   +3 more
openalex   +1 more source

SARS-CoV-2-reactive T cells in healthy donors and patients with COVID-19

open access: yesNature, 2020
Julian Braun   +32 more
semanticscholar   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

The Role of LAT–PLCγ1 Interaction in γδ T Cell Development and Homeostasis [PDF]

open access: bronze, 2014
Sarah Sullivan   +5 more
openalex   +1 more source

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