Results 181 to 190 of about 7,436,963 (336)

Confinement-optimized three-dimensional T cell amoeboid motility is modulated via myosin IIA–regulated adhesions

, 2010
Jordan Jacobelli, Rachel S. Friedman, Mary Anne Conti, Ana‐Maria Lennon‐Duménil, Matthieu Piel, Caitlin M. Sorensen, Robert Adelstein, Matthew F. Krummel   +7 more
openalex   +2 more sources

Ectopic Tcf1 expression instills a stem-like program in exhausted CD8+ T cells to enhance viral and tumor immunity [PDF]

, 2020
Qiang Shan, Shengen Shawn Hu, Xia Chen, Derek B. Danahy, Vladimir P. Badovinac, Chongzhi Zang, Hai‐Hui Xue   +6 more
openalex   +1 more source

CagA-specific Gastric CD8+ Tissue-Resident T Cells Control Helicobacter pylori During the Early Infection Phase [PDF]

, 2022
Maximilian R. Koch, Ruolan Gong, Verena Friedrich, Veronika Engelsberger, Lorenz Kretschmer, Andreas Wanisch, Sebastian Jarosch, Anna Ralser, Bob Lugen, Michael Quante, Michael Vieth, Riccardo Vasapolli, Christian Schulz, Veit R. Buchholz, Dirk H. Busch, Raquel Mejías‐Luque, Markus Gerhard   +16 more
openalex   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Suppression of P53 Pathway is an Important Factor Inducing Acute Graft-versus-Host Disease Through T Cell Activation Based on Bioinformatics Analysis

Journal of Inflammation Research
Shiyu Wang,1– 4 Wei Qin,1– 4 Tingting Cheng,1– 4 Cong Zeng,1– 4 Xu Chen,1– 4 Yajing Xu1– 4 1Department of Hematology, Xiangya Hospital, Central South University, Changsha, Hunan, People’s Republic of China; 2National Clinical Research Center for ...
Wang S, Qin W, Cheng T, Zeng C, Chen X, Xu Y   +5 more
doaj  

Human Immunodeficiency Virus Integrates Directly into Naive Resting CD4⁺T Cells but Enters Naive Cells Less Efficiently than Memory Cells [PDF]

, 2009
Jihong Dai, Luis M. Agosto, Clifford Baytop, Jianqing Yu, Matthew Pace, Megan K. Liszewski, Una O’Doherty   +6 more
openalex   +1 more source

Single-cell immune profiling reveals functional diversity of T cells in tuberculous pleural effusion [PDF]

, 2022
Yi Cai, Yejun Wang, Chenyan Shi, Youchao Dai, Fuxiang Li, Yuzhong Xu, Peize Zhang, Fanhui Kong, Guofang Deng, Zhihua Wen, Qi Zhou, Boxi Kang, Amit Singhal, Qianting Yang, Carl G. Feng, Xinchun Chen   +15 more
openalex   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Characteristics and anatomic location of PD-1 ⁺ TCF1 ⁺ stem-like CD8 T cells in chronic viral infection and cancer [PDF]

, 2023
Se Jin Im, Rebecca C. Obeng, Tahseen H. Nasti, Daniel T. McManus, Alice O. Kamphorst, Sivaram Gunisetty, Nataliya Prokhnevska, Jennifer W. Carlisle, Ke Yu, Gabriel Sica, Lucas Esteves Cardozo, André N. A. Gonçalves, Haydn Kissick, Helder I. Nakaya, Suresh S. Ramalingam, Rafi Ahmed   +15 more
openalex   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source