Results 161 to 170 of about 14,801,660 (264)

Human precursor T follicular regulatory cells are primed for differentiation into mature Tfr and disrupted during severe infections. [PDF]

Sci Adv
Tulyeu J, Søndergaard JN, Priest DG, Ebihara T, Matsumoto H, Llamas-Covarrubias MA, Imai M, Esaki S, Iwasaki S, Morita A, Yamazaki S, Sakaguchi S, Wing JB.   +12 more
europepmc   +1 more source

SAV1 in Cooperation With FKBP52 Participates in Implantation

Advanced Science, EarlyView.
The MST‐SAV1 complex modulates FKBP52 phosphorylation to fine‐tune PR activity, ensuring timely uterine transition to receptivity under estrogen signaling for implantation. Stromal SAV1 scaffolds MST1/2‐mediated FKBP52 phosphorylation via noncanonical Hippo to promote PR activity.
Yuhan Shao, Yafang Lu, Zhaoyu Jia, Junxiang Ren, Ziyi Ge, Xinyu Liu, Hui Zhao, Zi‐Jiang Chen, Junhao Yan, Wei Wang, Jia Yuan   +10 more
wiley   +1 more source

Editorial: Follicular Helper T Cells in Immunity and Autoimmunity

Frontiers in Immunology, 2020
Maria Pia Cicalese, Maria Pia Cicalese, Shahram Salek-Ardakani, Georgia Fousteri   +3 more
doaj   +1 more source

YiQiWenShen formula ameliorates myasthenia gravis through T follicular helper cells/T follicular regulatory cells immune rebalancing. [PDF]

Am J Transl Res
Rao K, Li Z, Huang C.
europepmc   +1 more source

CD86‐Positive Mature Tertiary Lymphoid Structures Are Associated With CD8+ T‐Cell Infiltration and Favorable Clinical Outcomes in Pancreatic Ductal Adenocarcinoma

Annals of Gastroenterological Surgery, EarlyView.
CD86‐positive mature tertiary lymphoid structures were associated with increased intratumoral CD8+ T‐cell infiltration, a higher proportion of Granzyme B‐expressing CD8+ T cells in an exploratory analysis, and favorable clinical outcomes in pancreatic ductal adenocarcinoma.
Takaomi Seki, Kenichiro Araki, Takehiko Yokobori, Hayato Ikota, Norio Kubo, Takamichi Igarashi, Mariko Tsukagoshi, Norihiro Ishii, Yasuo Hosouchi, Hiroshi Saeki, Ken Shirabe   +10 more
wiley   +1 more source

PD-1 and ICOS are coexpressed in T follicular helper cells but define three stages of maturation of T follicular regulatory cells. [PDF]

Sci Adv
Ribeiro F, Antunes D, Pires AR, Rino J, Filipe B, Jesus K, Correia R, Fonseca VR, Kumar S, Graca L.   +9 more
europepmc   +1 more source

Targeting B‐Cell‐Activating Factor and Its Receptor in Immune Thrombocytopenia and Warm Autoimmune Hemolytic Anemia

American Journal of Hematology, EarlyView.
ABSTRACT Current treatments for immune thrombocytopenia (ITP) and warm autoimmune hemolytic anemia (wAIHA), rare autoimmune diseases in which autoreactive B cells play a major role, can lead to high response rates; however, for many patients these responses are not durable or maintained after treatment discontinuation.
Matthieu Mahévas, Nichola Cooper, Vickie McDonald, Karina Yazdanbakhsh, Wilma Barcellini   +4 more
wiley   +1 more source

IL-12 drives the differentiation of human T follicular regulatory cells. [PDF]

Sci Immunol
Castaño D, Wang S, Atencio-Garcia S, Shields EJ, Rico MC, Sharpe H, Bustamante J, Feng A, Le Coz C, Romberg N, Tobias JW, Utz PJ, Henrickson SE, Casanova JL, Bonasio R, Locci M.   +15 more
europepmc   +1 more source

Establishment and characterization of mouse lymph node fibrosis models

Animal Models and Experimental Medicine, EarlyView.
The design of the entire paper. Schematic illustration of four strategies for establishing mouse lymph node (LN) fibrosis models. The study further compares their fibrotic remodeling patterns and immune alterations. Abstract Background Lymph node (LN) fibrosis occurs in a variety of pathological conditions, including HIV infection, obesity, cancer, and
Yaru Niu, Xu Guan, Jian Ma, Xin Zhang, Yihang Shi, Jinzhu Zhang, Leiqiong Gao, Wei Chen, Xishan Wang   +8 more
wiley   +1 more source

T follicular regulatory cells in food allergy promote IgE via IL-4. [PDF]

JCI Insight
Chen Q, Abdi AM, Luo W, Yuan X, Dent AL.
europepmc   +1 more source