Results 101 to 110 of about 1,267,388 (382)

FEATURES OF THE PHENOTYPE OF REGULATORY T CELLS IN EARLY AND ADVANCED RHEUMATOID ARTHRITIS

open access: yesНаучно-практическая ревматология, 2018
Objective: to analyze the levels of CD3+, CD3+CD4+, CD3+CD8+, and CD3-CD56+ T lymphocytes, FoxP3+ regulatory T cells (Treg), and CD19+ B lymphocytes in patients with early and advanced rheumatoid arthritis (RA). Subjects and methods.
A. S. Avdeeva   +5 more
doaj   +1 more source

DR-bearing T lymphocytes in thoracic duct lymph [PDF]

open access: yes, 1981
T cells having DR antigens were shown to be present in high numbers in the thoracic duct lymph of patients undergoing long-term drainage. As drainage progresses the proportion of T DR cells in the lymph increases to levels as high as 70% at 6 weeks ...
Abo   +25 more
core   +1 more source

Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha   +6 more
wiley   +1 more source

Multiscale model for the effects of adaptive immunity suppression on the viral therapy of cancer [PDF]

open access: yes, 2013
Oncolytic virotherapy - the use of viruses that specifically kill tumor cells - is an innovative and highly promising route for treating cancer. However, its therapeutic outcomes are mainly impaired by the host immune response to the viral infection.
arxiv   +1 more source

Guided assembly of cellular network models from knowledge in literature [PDF]

open access: yesarXiv, 2021
Computational modeling is crucial for understanding and analyzing complex systems. In biology, model creation is a human dependent task that requires reading hundreds of papers and conducting wet lab experiments, which would take days or months. To overcome this hurdle, we propose a novel automated method, that utilizes the knowledge published in ...
arxiv  

The role of regulatory T cells in the modulation of anti-tumor immune response [PDF]

open access: yesSrpski Arhiv za Celokupno Lekarstvo, 2013
It has been shown that the loss of regulatory function by deple­ + Regulatory T cells (Treg) represent a subset of CD4 T cells whose function is to suppress immune responses.
Radosavljević Gordana D.   +3 more
doaj   +1 more source

SPONTANEOUS-RECOVERY OF RATS FROM EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS IS DEPENDENT ON REGULATION OF THE IMMUNE-SYSTEM BY ENDOGENOUS ADRENAL CORTICOSTEROIDS [PDF]

open access: yes, 1989
Experimental allergic encephalomyelitis (EAE) ' is a paralytic disease that can be induced in a number of animal species by evoking immune responses to antigens in central nervous system (CNS) myelin, and has been studied as a model for multiple ...
Antoni, FA, MacPhee, IA, Mason, DW
core   +3 more sources

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

Mathematical modeling of escape of HIV from cytotoxic T lymphocyte responses [PDF]

open access: yes, 2012
Human immunodeficiency virus (HIV-1 or simply HIV) induces a persistent infection, which in the absence of treatment leads to AIDS and death in almost all infected individuals. HIV infection elicits a vigorous immune response starting about 2-3 weeks post infection that can lower the amount of virus in the body, but which cannot eradicate the virus ...
arxiv   +1 more source

HoechstGAN: Virtual Lymphocyte Staining Using Generative Adversarial Networks [PDF]

open access: yesarXiv, 2022
The presence and density of specific types of immune cells are important to understand a patient's immune response to cancer. However, immunofluorescence staining required to identify T cell subtypes is expensive, time-consuming, and rarely performed in clinical settings.
arxiv  

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