Results 191 to 200 of about 1,267,388 (382)
Nature of the Antigenic Complex Recognized by T Lymphocytes [PDF]
, 1978 David W. Thomas, Ethan M. Shevach
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Acta Biomedica Scientifica, 2012 The aim of the present study was a comparative assessment of the cytotoxic activity of IFNα-induced dendritic cells (IFN-DCs) and IL-4-induced DCs (IL4-DCs) against allo-MLC- activated CD4+ and CD8+T-lymphocytes.
T. V. Tyrinova +4 more
doaj
Immunological MedicineOur aim is to determine the number of leukocytes, T lymphocytes and B lymphocytes and the expression of activation markers CD200 and CD23 on B lymphocytes in atopic dermatitis (AD) patients (treated and not treated with dupilumab) during the pollen ...
Jarmila Čelakovská +4 more
doaj +1 more source
Dendrimer Conjugates with PD‐L1‐Binding Peptides Enhance In Vivo Antitumor Immune Response
Advanced Healthcare Materials, EarlyView.In this paper, a novel nanoparticle scaffold composed of dendrimers conjugated with peptide‐based immune checkpoint inhibitors, enhancing drug delivery efficacy is introduced. By conjugating PD‐L1‐binding peptides to dendrimers, multivalent binding effects are harnessed, resulting in enhanced binding affinity, prolonged half‐life, and improved ...
DaWon Kim +11 more
wiley +1 more source
Cell Interactions between Histoincompatible T and B Lymphocytes. V. Failure of Histoincompatible T Cells to Interfere with Physiologic Cooperation between Syngeneic T and B Lymphocytes [PDF]
, 1974 David H. Katz +3 more
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Geometric Adjustment of T Cell‐Sensitive Nanorobots for Enhanced Stability
Advanced Healthcare Materials, EarlyView.For the long‐term use of live dendritic cell (DC)‐based vaccines, nano bone marrow dendritic cell (BMDC) originated T cell activators (nano‐BOTs) are synthesized. The geometric properties of nanoparticles are precisely modulated, enhancing their stability and T cell activation capacity.
Yoojin Lee +11 more
wiley +1 more source
Nature of T Lymphocyte Recognition of Macrophage-Associated Antigens [PDF]
, 1979 David W. Thomas +2 more
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Engineering CAR‐T Therapeutics for Enhanced Solid Tumor Targeting
Advanced Materials, EarlyView.CART cell therapy has proven effective for blood cancers but struggles with solid tumors due to diverse antigens and complex environments. Recent efforts focus on improving CAR design and validation platforms. Advances in protein engineering, machine learning, and organoid systems aim to enhance CAR‐T therapy against solid tumors.
Danqing Zhu +4 more
wiley +1 more source
T Lymphocyte-Mediated Suppression of Myeloma Function in Vitro [PDF]
, 1979 Abul K. Abbas
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Advanced Materials, EarlyView.The CDs crosslinked egg white hydrogel loaded with lipopolysaccharide (LPS) and CA170 (TTF‐L‐C) can realize spatiotemporal tumor‐associated macrophages (TAMs) transformation from multi‐level dimensions, including spatial recruitment, cell phenotype reprogramming, and immune checkpoint molecule blockade.
Lingyun Li +8 more
wiley +1 more source