Results 201 to 210 of about 12,046,757 (352)

Pre‐Encoded IFN‐I Sensitivity Exacerbates Memory T Cell Senescence in Solid Tumors

Advanced Science, EarlyView.
Type I interferon (IFN‐I) signaling promotes p21‐dependent cell cycle arrest in senescent tumor‐specific memory T cells, resulting in poor proliferative responses and solid tumor regression during cancer vaccination. Conversely, IFNα/β receptor blockade reinvigorates T cell proliferation to regress solid tumors and is more effective with increasing ...
Andrew Nguyen, Scott R Walsh, Li Deng, Lan Chen, Yonghong Wan   +4 more
wiley   +1 more source

Bexarotene signaling in human B and T lymphocytes induces gut-homing receptor expression. [PDF]

Front Immunol
Kaiser S, Suhrkamp I, He J, Helf C, Sadik CD, Weichenthal M, Heine G.   +6 more
europepmc   +1 more source

T cell receptor repertoire in mucosal lymphocytes of patients with inflammatory bowel disease

, 1994
Takuya Matsumoto, W.R. Brown, Atsuo Kitano, Keita Adachi, Shinichiro Nakamura, Yasuhiro Watanabe, T. Aoki, A. Obata, N. Oshitani, Thomas Prindiville, Mary C. Cantrell, E. Gershwin, Brian L. Kotzin   +12 more
openalex   +1 more source

T Cell Glycoengineering to Modulate Immune‐Tumor Crosstalk: A Universal Non‐Genetic Strategy for Enhanced Tumor Immunotherapy

Advanced Science, EarlyView.
This study describes a T cell surface engineering strategy that integrates polymer materials with tumor immunology, aiming to achieve broad‐spectrum anti‐tumor applications of glycopolymer‐engineered T (G‐T) cells via non‐genetic modification. Glycopolymer engineering generally modulates immune‐tumor crosstalk through specific cell‐cell interactions ...
Lihua Yao, He Yang, Fangjian Shan, Xiaomeng Niu, Yichen Wang, Hengyuan Zhang, Sujian Wang, Gaojian Chen, Hong Chen   +8 more
wiley   +1 more source

CD38 promotes LPS-induced innate-like activation and proliferation of CD8⁺ T lymphocytes in aged mice. [PDF]

Front Aging
Santiago-Cruz W, Espinosa E, Pérez-Lara JC, Romero-Ramírez H, Devarajan P, García-García F, Rodríguez-Alba JC.   +6 more
europepmc   +1 more source

Staphylococcal toxin-induced T cell proliferation in atopic eczema correlates with increased use of superantigen-reactive Vβ-chains in cutaneous lymphocyte-associated antigen (CLA)-positive lymphocytes [PDF]

, 2000
S. C. Davison, Michael Allen, Robert Vaughan, Juliet N. Barker   +3 more
openalex   +1 more source

FAPα+ Macrophages Orchestrate Immune Evasion in Multiple Myeloma by Dual Regulation of PD‐L1 and T Cell Senescence

Advanced Science, EarlyView.
ABSTRACT Multiple myeloma (MM) is a hematologic malignancy driven by clonal expansion of malignant plasma cells. Despite the long‐term disease control achieved with immunotherapies in some patients, treatment resistance remains a major cause of disease relapse.
Huiyao Gu, Zhenfeng Dai, Xi Huang, Enfan Zhang, Xinyuan Dai, Haoguang Chen, Wen Cao, Jinna Zhang, Yifan Hou, Haimeng Yan, Yang Yang, Li Yang, Yi Li, Wenlong Lin, Zhen Cai, Jingsong He   +15 more
wiley   +1 more source

Development of a novel in vitro micronucleus test using human induced pluripotent stem cell-derived T lymphocytes. [PDF]

Genes Environ
Kobayashi R, Sasaki K, Matsuyama R, Saito K, Kumagai A, Kitayama S, Kawai Y, Kaneko S.   +7 more
europepmc   +1 more source

Acute Laryngitis in the Rat Induced by Moraxella catarrhalis and Bordetella pertussis: Number of Neutrophils, Dendritic Cells, and T and B Lymphocytes Accumulating during Infection in the Laryngeal Mucosa Strongly Differs in Adjacent Locations [PDF]

, 1999
Peter Jecker, Andrew McWilliam, Sylvia Napoli, Patrick G. Holt, Reinhard Pabst, Martin Westhofen, Jürgen Westermann   +6 more
openalex   +1 more source

Programmed cell death 1 ligand 1 and tumor-infiltrating CD8+ T lymphocytes are prognostic factors of human ovarian cancer

Proceedings of the National Academy of Sciences of the United States of America, 2007
J. Hamanishi, M. Mandai, Masashi Iwasaki, Taku Okazaki, Yoshimasa Tanaka, K. Yamaguchi, T. Higuchi, H. Yagi, K. Takakura, N. Minato, T. Honjo, S. Fujii   +11 more
semanticscholar   +1 more source