Results 31 to 40 of about 7,179 (272)

Emerging technologies for the non-invasive characterization of physical-mechanical properties of tablets [PDF]

open access: yes, 2017
The density, porosity, breaking force, viscoelastic properties, and the presence or absence of any structural defects or irregularities are important physical-mechanical quality attributes of popular solid dosage forms like tablets.
Chougule, Mahavir B.   +4 more
core   +2 more sources

A classification system for tableting behaviors of binary powder mixtures

open access: yesAsian Journal of Pharmaceutical Sciences, 2016
The ability to predict tableting properties of a powder mixture from individual components is of both fundamental and practical importance to the efficient formulation development of tablet products.
Changquan Calvin Sun
doaj   +1 more source

Impact of Particle and Equipment Properties on Residence Time Distribution of Pharmaceutical Excipients in Rotary Tablet Presses

open access: yesPharmaceutics, 2020
Paddle feeders are devices commonly used in rotary tablet presses to facilitate constant and efficient die filling. Adversely, the shear stress applied by the rotating paddles is known to affect the bulk properties of the processed powder dependent on ...
Daniel Puckhaber   +3 more
doaj   +1 more source

Experimental Elucidation of Templated Crystallization and Secondary Processing of Peptides

open access: yesPharmaceutics, 2023
The crystallization of peptides offers a sustainable and inexpensive alternative to the purification process. In this study, diglycine was crystallised in porous silica, showing the porous templates’ positive yet discriminating effect.
Vivek Verma   +3 more
doaj   +1 more source

Continuous direct compression as manufacturing platform for sustained release tablets [PDF]

open access: yes, 2017
This study presents a framework for process and product development on a continuous direct compression manufacturing platform. A challenging sustained release formulation with high content of a poorly flowing low density drug was selected.
Cunningham, C.   +7 more
core   +1 more source

The influence of fillers on theophylline release from clay matrices [PDF]

open access: yes, 2015
: The objectives of this study were to investigate the suitability of magnesium aluminium silicate (MAS) (Veegum®) to control drug release of a model drug, theophylline, from tablet matrices.
Adebisi, Adeola O.   +2 more
core   +1 more source

Scaled-up preparation of drug-loaded electrospun polymer fibres and investigation of their continuous processing to tablet form

open access: yeseXPRESS Polymer Letters, 2018
Polymer-based electrospun amorphous solid dispersions (ASDs) were prepared and investigated from pharmaceutical application point of view. Spironolactone (SPIR) was used as model drug mixed in various concentrations with polymers suitable for fibre ...
E. Szabo   +10 more
doaj   +1 more source

Compaction Properties of Particulate Proteins in Binary Powder Mixtures with Common Excipients

open access: yesPharmaceutics, 2023
The increasing interest in protein- and peptide-based oral pharmaceuticals has culminated in the first protein-based products for oral delivery becoming commercially available.
Else Holmfred   +2 more
doaj   +1 more source

Impact of blend properties on die filling during tableting [PDF]

open access: yes, 2018
Based on characterization of a wide range of fillers and APIs, thirty divergent blends were composed and subsequently compressed on a rotary tablet press, varying paddle speed and turret speed.
De Beer, Thomas   +8 more
core   +1 more source

The Challenge of Die Filling in Rotary Presses—A Systematic Study of Material Properties and Process Parameters

open access: yesPharmaceutics, 2020
For the efficient and safe production of pharmaceutical tablets, a deep process understanding is of high importance. An essential process step during tableting is the die filling, as it is responsible for a consistent tablet weight and drug content ...
Ann Kathrin Schomberg   +2 more
doaj   +1 more source

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