Results 241 to 250 of about 1,564 (279)

Reliable Detection of Chemical Warfare Agents Using High Kinetic Energy Ion Mobility Spectrometry. [PDF]

J Am Soc Mass Spectrom
Schaefer C, Allers M, Hitzemann M, Nitschke A, Kobelt T, Mörtel M, Schröder S, Ficks A, Zimmermann S.   +8 more
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Toxicokinetics of tabun enantiomers in anaesthetized swine after intravenous tabun administration

Toxicology Letters, 2010
In the present study, we report the first in vivo toxicokinetic study of tabun (O-ethyl-N,N-dimethylphosphoramidocyanidate). The toxicokinetics of the enantiomers of tabun were investigated in anesthetized swine after intravenous administration of 3xLD(50) (161.4mug/kg) tabun.
O, Tenberken, J, Mikler, I, Hill, K, Weatherby, H, Thiermann, F, Worek, G, Reiter   +6 more
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Sarin, Soman, Tabun und VX

Notfall & Rettungsmedizin, 2002
Lange Zeit war ein chemischer Kampfmittelangriff ein militarisches Szenario. Spatestens seit der Attacke mit Sarin auf die Tokioter U-Bahn im Jahre 1995 durch den Aum-Shinrikyo-Kult werden zivile Kampfstoffeinsatze in den Szenarien von vielen Katastrophenplanern mit einbezogen.
T. Bey, F. G. Walter
openaire   +1 more source

Novel and selective detection of Tabun mimics

Chem. Commun., 2014
Detection of nerve agent-related molecules based on BODIPY–salicylaldehyde oxime conjugation was studied.
Jang, YJ Jang, Yoon Jeong, Tsay, OG Tsay, Olga G., Murale, DP Murale, Dhiraj P., Jeong, JA Jeong, Jeong A., Segev, A Segev, Aviv, Churchill, DG Churchill, DG   +5 more
openaire   +3 more sources

Toxogonin in Sarin, Soman and Tabun poisoning

Biochemical Pharmacology, 1965
The oximes P2S, TMB-4 and Toxogonin have been tested as reactivators of Sarin and Tabun inhibited acetylcholinesterase. The protective effect of the oximes has been studied on atropinized mice in experimental Sarin, Soman and Tabun poisoning. Toxogonin is a better reactivator than P2S and comparable to TMB-4. In the presence of 10 mg/kg atropine (i.p.)
E, HEILBRONN, B, TOLAGEN
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Effective bisquaternary reactivators of tabun‐inhibited AChE

Journal of Applied Toxicology, 2005
AbstractTwo cholinesterase reactivators (K074 and K075) were synthesized and their reactivation efficacy against tabun‐inhibited acetylcholinesterase of the rat brain was tested in vitro. Comparing this efficacy showed that commonly used oximes (pralidoxim, obidoxime and HI‐6) were practically without reactivation potency.
Kamil, Kuca, Jiri, Cabal, Kamil, Musilek, Daniel, Jun, Jiri, Bajgar   +4 more
openaire   +2 more sources

Genotoxicity of the phosphoramidate agent tabun (GA)

Toxicology, 1994
Five mutagenicity tests were performed on Agent GA (Tabun, phosphoramidocyanidic acid, dimethyl-, ethyl ester) as part of a program to demilitarize chemical warfare agents. GA was mutagenic in Salmonella spp. assays with S-9 and it was a direct-acting mutagen to mouse lymphoma cells.
B W, Wilson, T G, Kawakami, N, Cone, J D, Henderson, L S, Rosenblatt, M, Goldman, J C, Dacre   +6 more
openaire   +2 more sources

Tabun-Khara-Obo, Mongolia

2019
The Tabun-Khara-Obo impact crater is situated in a remote part of the eastern Gobi Desert, about 470 km southeast of Ulaanbaatar, and it interrupts a northeast–southwest-striking sedimentary massif that is deeply etched by prevailing winds.
Goro Komatsu, Alessandro Coletta, Maria Libera Battagliere, Maria Virelli   +3 more
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Tabun scavengers based on hydroxamic acid containing cyclodextrins

Chemical Communications, 2013
Arrangement of several hydroxamic acid-derived substituents along the cavity of a cyclodextrin ring leads to compounds that detoxify tabun in TRIS-HCl buffer at physiological pH and 37.0 °C with half-times as low as 3 min.
Florian, Brandhuber, Michael, Zengerle, Luzian, Porwol, Anne, Bierwisch, Marianne, Koller, Georg, Reiter, Franz, Worek, Stefan, Kubik   +7 more
openaire   +2 more sources