Results 21 to 30 of about 73,761 (306)

Cambios en la homeostasis de la glucosa y la proliferación de la célula beta pancreática tras el cambio a ciclosporina en la diabetes inducida por tacrolimus

Nefrología, 2015
Antecedentes: El cambio a ciclosporina A podría revertir la diabetes inducida por tacrolimus. Sin embargo, los mecanismos de esta reversibilidad se desconocen. Métodos: Usamos como modelo de diabetes inducida por tacrolimus las ratas Zucker obesas.
Ana Elena Rodríguez-Rodríguez, Javier Triñanes, Esteban Porrini, Silvia Velázquez-García, Cecilia Fumero, María Jose Vega-Prieto, María Luisa Díez-Fuentes, Sergio Luis Lima, Eduardo Salido, Armando Torres   +9 more
doaj   +1 more source

Glucose homeostasis changes and pancreatic β-cell proliferation after switching to cyclosporin in tacrolimus-induced diabetes mellitus

Nefrología (English Edition), 2015
Background: Switching to cyclosporin A may result in a reversion of tacrolimus-induced diabetes mellitus. However, mechanisms underlying such a reversion are still unknown.
Ana Elena Rodríguez-Rodríguez, Javier Triñanes, Esteban Porrini, Silvia Velázquez-García, Cecilia Fumero, María Jose Vega-Prieto, María Luisa Díez-Fuentes, Sergio Luis Lima, Eduardo Salido, Armando Torres   +9 more
doaj   +1 more source

Population pharmacokinetics and initial dose optimization of tacrolimus in children with severe combined immunodeficiency undergoing hematopoietic stem cell transplantation

Frontiers in Pharmacology, 2022
The present study aimed to explore the population pharmacokinetics and initial dose optimization of tacrolimus in children with severe combined immunodeficiency (SCID) undergoing hematopoietic stem cell transplantation (HSCT).
Xiao Chen, Dongdong Wang, Feng Zheng, Xiaowen Zhai, Hong Xu, Zhiping Li   +5 more
doaj   +1 more source

Case Report: Acute Pancreatitis Associated With Tacrolimus in Kidney Transplantation and a Review of the Literature

Frontiers in Medicine, 2022
BackgroundDrug-induced pancreatitis is a rare cause of acute pancreatitis. Tacrolimus has been used as an immunosuppressant agent in patients after organ transplantation. However, only a few case reports of tacrolimus-induced acute pancreatitis in kidney
Yixuan Ding, Yixuan Ding, Chang Qu, Chang Qu, Huan He, Feng Cao, Feng Cao, Tongwen Ou, Fei Li, Fei Li   +9 more
doaj   +1 more source

Tacrolimus in Renal Transplantation [PDF]

, 2008
Tacrolimus (Prograf-FK506) has been used since 1989 as a primary immunosuppressive agent in adult and pediatric renal transplant recipients at our institution.1,2 This report will summarize our experience with it over the past six years and will demonstrate its overall efficacy and superiority.
Shapiro, R, Jordan, ML, Scantlebury, VP, Vivas, C, Gritsch, HA, McCauley, J, Ellis, D, Gilboa, N, Lombardozzi-Lane, S, Randhawa, P, Demetris, AJ, Irish, W, Hakala, TR, Simmons, RL, Fung, JJ, Starzl, TE   +15 more
openaire   +3 more sources

Effects of the CYP3A4*1B Genetic Polymorphism on the Pharmacokinetics of Tacrolimus in Adult Renal Transplant Recipients: A Meta-Analysis. [PDF]

PLoS ONE, 2015
BACKGROUND AND OBJECTIVE:The association between the CYP3A4*1B single nucleotide polymorphism (SNP) and tacrolimus pharmacokinetics in different studies is controversial.
Wei-Long Shi, Hui-Lin Tang, Suo-Di Zhai
doaj   +1 more source

Tacrolimus in membranous nephropathy [PDF]

Kidney International, 2008
To the Editor: In a recent issue of the Journal, Praga et al.1 reported their experience with tacrolimus monotherapy in patients with idiopathic membranous nephropathy. The authors concluded that tacrolimus was a very useful therapeutic option. This conclusion was based on the findings of a higher remission rate and a reduced risk of deterioration of ...
openaire   +3 more sources

A shared mucosal gut microbiota signature in primary sclerosing cholangitis before and after liver transplantation

Hepatology, EarlyView., 2022
In this study of the gut mucosal microbiota in primary sclerosing cholangitis (PSC), we found consistent microbiota features associated with PSC and recurrent PSC, PSC with inflammatory bowel disease and a persistent gut dysbiosis after liver transplantation Abstract Background and Aims Several characteristic features of the fecal microbiota have been ...
Mikal Jacob Hole, Kristin Kaasen Jørgensen, Kristian Holm, Peder R. Braadland, Malin Holm Meyer‐Myklestad, Asle Wilhelm Medhus, Dag Henrik Reikvam, Alexandra Götz, Krzysztof Grzyb, Kirsten Muri Boberg, Tom Hemming Karlsen, Martin Kummen, Johannes R. Hov   +12 more
wiley   +1 more source

Variability of Tacrolimus Trough Concentration in Liver Transplant Patients: Which Role of Inflammation?

Pharmaceutics, 2021
Tacrolimus presents high intra and inter-individual variability in its blood trough concentration (Cmin). Knowledge of the factors that are involved in tacrolimus Cmin variability is thus clinically important to prevent or limit it.
Anaelle Chavant, Xavier Fonrose, Elodie Gautier-Veyret, Marie Noelle Hilleret, Matthieu Roustit, Francoise Stanke-Labesque   +5 more
doaj   +1 more source

Systematic external evaluation of published population pharmacokinetic models for tacrolimus in adult liver transplant recipients [PDF]

Eur.J.Pharm.Sci.145(2020)105237, 2019
Background:Diverse tacrolimus population pharmacokinetic models in adult liver transplant recipients have been established to describe the PK characteristics of tacrolimus in the last two decades. However, their extrapolated predictive performance remains unclear.Therefore,in this study,we aimed to evaluate their external predictability and identify ...
arxiv   +1 more source