Results 41 to 50 of about 82,830 (185)

The level of intracellular tacrolimus in T cell is affected by CD44 ABCB1 activities triggered by inflammation

European Journal of Inflammation, 2019
Rejection is an important issue in kidney transplant. Although with adequate trough level of tacrolimus, acute rejection occurs, and we are focused on these cases.
Eunjin Bae, Seung Seok Han, Dong Jun Park, Hajeong Lee, Mi-Yeon Yu, Kyu Hong Kim, Min Chang Kim, Joo-Youn Cho, Sang-Il Min, Jongwon Ha, Yon Su Kim, Seung Hee Yang   +11 more
doaj   +1 more source

Suplatast/Tacrolimus Combination Therapy for Refractory Facial Erythema in Adult Patients with Atopic Dermatitis—A Meta-Analysis Study—

Allergology International, 2007
Background: Combination of suplatast tosilate with tacrolimus ointment was reported to reduce the dose of tacrolimus ointment with maintained treatment efficacy for refractory facial erythema in atopic dermatitis (AD), however these were only case ...
Yoshiki Miyachi, Ichiro Katayama, Masutaka Furue   +2 more
doaj   +1 more source

Pulmonary delivery of tacrolimus for lung transplant and asthma therapy [PDF]

, 2009
textSince the discovery of cyclosporine in 1971, calcineurin inhibitors have played a critical role in the therapeutic suppression of the immune response.
Watts, Alan Bayard, 1981-
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Improved kidney function and one-year survival with transitioning from intravenous to enteral tacrolimus in lung transplant recipients

Transplantation Reports
Background: Acute kidney injury (AKI) is common after lung transplant and may increase risk of chronic kidney disease (CKD). Calcineurin inhibitors (CNIs) such as tacrolimus contribute to AKI risk.
Carrie Burt, Georgina Waldman, Linda Awdishu, Kamyar Afshar, Mark Mariski, Jade Kozuch, Gordon Yung, Eugene Golts, Ashley Feist   +8 more
doaj   +1 more source

Tacrolimus‐Related Neurotoxicity of the Pons in Children: Review of the Literature and a Case Report

Annals of the Child Neurology Society
Introduction Tacrolimus is a potent immunosuppressive agent effective in preventing solid organ transplant rejection. It is widely used following allogeneic liver, kidney, heart, and bone marrow transplantation.
Amy Hill, Mohamed Bilal Haradwala, Jean‐Baptiste Le Pichon   +2 more
doaj   +1 more source

Analysis of the histology of the scar bladder and biochemical parameters of rats with a solitary kidney undergoing immunosuppression with tacrolimus [PDF]

Acta Cirúrgica Brasileira, 2014
PURPOSE:To evaluate bladder histology in healing and biochemical analysis of rats with single kidney in ischemia/reperfusion, treated with tacrolimus.METHODS: Fifty rats randomized into five groups.
Ricardo Cavalheiro Cavalli, Renato Tambara Filho, Regina de Paula Xavier Gomes, Djanira Aparecida da Luz Veronez, Julio Slongo, Rogério de Fraga   +5 more
doaj   +1 more source

The Association of Tacrolimus Formulation on Cerebral Blood Flow and Cognitive Function

Transplantation Direct, 2023
Background. Calcineurin inhibitors are inherent vasoconstrictors. Cerebral vasoconstriction can reduce cerebral blood flow (CBF), and negatively impact cerebrovascular response (CVR) to exercise, and cognitive function.
Irisa Mahaparn, MD, Rebecca J. Lepping, PhD, Robert N. Montgomery, PhD, Rishav Mukherjee, MSc, Sandra A. Billinger, PhD, William M. Brooks, PhD, Aditi Gupta, MD   +6 more
doaj   +1 more source

Optimizing tacrolimus treatment in kidney transplant recipients

, 2017
After kidney transplantation, lifelong treatment with immunosuppressive drugs is needed. Tacrolimus is an essential part of most immunosuppressive regimens that are used today.
Størset, Elisabet
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Plasma Versus Whole Blood Tacrolimus Concentrations and Health-Related Quality of Life in Kidney Transplant Recipients

Pharmaceutics
Background/Objectives: Tacrolimus dosing traditionally relies on therapeutic drug monitoring in whole blood, while assessment in plasma may better reflect its effect and reveal overdosing impacting health-related quality of life (HRQoL). Methods: In this
Svea Nolte, J. Casper Swarte, Tim J. Knobbe, Ilja M. Nolte, Tanja R. Zijp, Harmen R. Moes, Marco van Londen, Niels L. Riemersma, Johannes R. Björk, Rinse K. Weersma, Gea Drost, Stefan P. Berger, Daan J. Touw, Stephan J. L. Bakker   +13 more
doaj   +1 more source

Tacrolimus in preventing transplant rejection in Chinese patients – optimizing use [PDF]

, 2015
Chuan-Jiang Li,1,* Liang Li2,* 1Department of Surgery, Nanfang Hospital, 2Department of Medical Genetics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, People’s Republic of China *The authors contributed equally ...
Li CJ, Li L
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