Results 31 to 40 of about 82,830 (185)

Importance of hematocrit for a tacrolimus target concentration strategy [PDF]

, 2013
Purpose To identify patient characteristics that influence tacrolimus individual dose requirement in kidney transplant recipients. Methods Data on forty-four 12-h pharmacokinetic profiles from 29 patients and trough concentrations in 44 patients measured
Midtvedt, Karsten, Nick Holford, Størset, Elisabet, Bergan, Stein, Karsten Midtvedt, Anders Åsberg, Sara Bremer, Holford, Nick, Bremer, Sara, Stein Bergan, Åsberg, Anders, Elisabet Størset   +11 more
core   +1 more source

Comparative Study of the Cellular Pharmacodynamics of Tacrolimus in Renal Transplant Recipients Treated with and without Basiliximab

Cell Transplantation, 2012
Basiliximab is a recently developed immunosuppressive agent for the prevention of acute allograft rejection in renal transplant recipients. The combination use of basiliximab and a calcineurin inhibitor was suggested to be more effective in comparison to
Kentaro Sugiyama Ph.D., Kazuya Isogai, Satoshi Horisawa, Akira Toyama, Hiroshi Satoh, Kazuhide Saito, Yuki Nakagawa, Masayuki Tasaki, Kota Takahashi, Toshihiko Hirano   +9 more
doaj   +1 more source

Effects of the CYP3A4*1B Genetic Polymorphism on the Pharmacokinetics of Tacrolimus in Adult Renal Transplant Recipients: A Meta-Analysis. [PDF]

PLoS ONE, 2015
BACKGROUND AND OBJECTIVE:The association between the CYP3A4*1B single nucleotide polymorphism (SNP) and tacrolimus pharmacokinetics in different studies is controversial.
Wei-Long Shi, Hui-Lin Tang, Suo-Di Zhai
doaj   +1 more source

Variability of Tacrolimus Trough Concentration in Liver Transplant Patients: Which Role of Inflammation?

Pharmaceutics, 2021
Tacrolimus presents high intra and inter-individual variability in its blood trough concentration (Cmin). Knowledge of the factors that are involved in tacrolimus Cmin variability is thus clinically important to prevent or limit it.
Anaelle Chavant, Xavier Fonrose, Elodie Gautier-Veyret, Marie Noelle Hilleret, Matthieu Roustit, Francoise Stanke-Labesque   +5 more
doaj   +1 more source

A case report: acute pancreatitis associated with tacrolimus in kidney transplantation

BMC Nephrology, 2019
Background Tacrolimus has been widely used for immunosuppressive therapy in solid organ transplantation (SOT) and allo-geneic stem cell transplantation (allo-SCT) over the past 2 decades.
Junnan Xu, Liang Xu, Xing Wei, Xiang Li, Ming Cai   +4 more
doaj   +1 more source

Pharmacokinetics of Tacrolimus in Egyptian Liver Transplant Recipients: Role of the Classic Co-variables [PDF]

Journal of Advanced Pharmacy Research, 2019
Objectives: This work was performed to study the pharmacokinetics of tacrolimus in adult liver transplant recipients after optimization of all the known classic factors contributing to inter-patient variability in whole blood tacrolimus levels.
Abdel-hamid Ebid, Sara Mohamed, Ahmed Mira, Aya Saleh   +3 more
doaj   +1 more source

Estudo do tacrolimus sobre a resposta inflamatória induzida pela carragenina no modelo da bolsa de ar, em camundongos [PDF]

, 2008
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Programa de Pós-Graduação em Farmácia.Introdução: Tacrolimus é um imunossupressor da classe dos macrolídeos utilizado na clínica para evitar a regeição em ...
Vigil, Silvana Virginia Gagliotti
core  

Tacrolimus for the Treatment of Ulcerative Colitis [PDF]

Intestinal Research, 2015
Tacrolimus is a calcineurin inhibitor used for the treatment of corticosteroid-refractory ulcerative colitis (UC). Two randomized controlled trials and a number of retrospective studies have assessed the therapeutic effect of tacrolimus in UC patients ...
Katsuyoshi Matsuoka, Eiko Saito, Toshimitsu Fujii, Kento Takenaka, Maiko Kimura, Masakazu Nagahori, Kazuo Ohtsuka, Mamoru Watanabe   +7 more
doaj   +1 more source

Estudo do efeito antiinflamatório do tacrolimus no modelo de pleurisia, em camundongos [PDF]

, 2006
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Programa de Pós-Graduação em Ciências Médicas.Introdução: O tacrolimus é um agente imunossupressor isolado do Streptomyces tsukubaensis e é utilizado ...
Pereira, Robson Roman
core  

Hemoglobin and total bilirubin may affect tacrolimus clearance in liver transplant patient following the early postoperative period: a case report

Journal of Medical Case Reports
Background Tacrolimus is a potent calcineurin inhibitor (CNI) that is principally used as a first-line immunosuppressant for the prophylaxis of allograft rejection in liver transplantation (LT) patients.
Vichapat Tharanon, Pansa Iamrahong, Jutamas Tuamsem, Kunvadee Choochaeam, Titinun Auamnoy, Abhasnee Sobhonslidsuk   +5 more
doaj   +1 more source