Results 61 to 70 of about 130,661 (316)

Tacrolimus [PDF]

Reactions Weekly, 2021
  +4 more sources

Liver transplantation [PDF]

, 2014
Purpose of review: Long-term survival of liver transplant recipients is threatened by increased rates of de-novo malignancy and recurrence of hepatocellular carcinoma (HCC), both events tightly related to immunosuppression.
Burroughs, AK, De la Mata, M, Rodríguez-Perálvarez, M   +2 more
core  

HLA and cross-reactive antigen group matching for cadaver kidney allocation [PDF]

, 1997
Background. Allocation of cadaver kidneys by graded human leukocyte antigen (HLA) compatibility scoring arguably has had little effect on overall survival while prejudicing the transplant candidacy of African-American and other hard to match populations.
Allan Donner, Azuma, Beatty, Bodmer, Brenner, Callender, Chertow, D'Alessandro, David Gjertson, Duquesnoy, Gaston, Gjertson, Guttman, Held, Joan Martell, John J. Fung, John McMichael, Maldonado, Massimo Trucco, Meuwissen, Michael Eliasziw, Mickey, Mickey, Norman, Opelz, Opelz, Paul I. Terasaki, Petersdorf, Petersdorf, Port, Rapaport, Rapaport, Rodey, Rodey, Ron Shapiro, Sanfilippo, Shapiro, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Takemoto, Takemoto, Terasaki, Terasaki, Thomas E. Starzl, Thompson, Van Buren, Velma Scantlebury   +54 more
core   +1 more source

Nirmatrelvir/ritonavir treatment in SARS-CoV-2 positive kidney transplant recipients – a case series with four patients

BMC Nephrology, 2023
Background Despite vaccination coronavirus disease 2019 (COVID-19)-associated mortality caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remains high in kidney transplant recipients.
Johanna Schneider, Rika Wobser, Wolfgang Kühn, Dirk Wagner, Yakup Tanriver, Gerd Walz   +5 more
doaj   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Dermal Delivery of the High-Molecular-Weight Drug Tacrolimus by Means of Polyglycerol-Based Nanogels [PDF]

, 2019
Polyglycerol-based thermoresponsive nanogels (tNGs) have been shown to have excellent skin hydration properties and to be valuable delivery systems for sustained release of drugs into skin.
Blume-Peytavi, Ulrike, Calderón, Marcelo, Giulbudagian, Michael, Kleuser, Burkhard, Rancan, Fiorenza, Schumacher, Fabian, Stanko, Jessica Isolde, Vogt, Annika, Volkmann, Hildburg   +8 more
core   +3 more sources

Focal Hypertrichosis during Topical Tacrolimus Therapy for Vitiligo: A Case Report

Case Reports in Dermatology
Introduction: Tacrolimus is widely used in treating vitiligo. Drug-induced hypertrichosis is a well-known side effect of cyclosporine. It is less commonly associated with tacrolimus or with topical calcineurin inhibitors.
Lingyu Mao, Yan Lin, Xueping Yu, Huaxu Liu   +3 more
doaj   +1 more source

Loss of SOCS1 in Donor T Cells Exacerbates Intestinal GVHD by Driving a Chemokine‐Dependent Pro‐Inflammatory Immune Microenvironment

Advanced Science, EarlyView.
T cell‐specific Socs1 knockout leads to inflammatory differentiation of CD8+ T cells, prompting the STAT1/2 complex to drive the activation of Ccl5, Ccr5, and Cxcr3, and promoting the skewing of monocytes toward a pro‐inflammatory M1 macrophage lineage.
Zhigui Wu, Bixia Wang, Xinya Jiang, Fangqing Zhang, Qianqian Huang, Xinyi Wu, Shuang Fan, Qi Zhang, Jingrui Zhou, Jianing Tang, Xiao‐Dong Mo, Yu Wang, Ying‐Jun Chang, Huidong Guo, Xiao‐Jun Huang   +14 more
wiley   +1 more source

CYP3A-status is associated with blood concentration and dose-requirement of tacrolimus in heart transplant recipients

Scientific Reports, 2021
High inter-individual variability in tacrolimus clearance is attributed to genetic polymorphisms of CYP3A enzymes. However, due to CYP3A phenoconversion induced by non-genetic factors, continuous changes in tacrolimus-metabolizing capacity entail ...
Máté Déri, Zsófia Szakál-Tóth, Ferenc Fekete, Katalin Mangó, Evelyn Incze, Annamária Minus, Béla Merkely, Balázs Sax, Katalin Monostory   +8 more
doaj   +1 more source

Risk Factors for Small‐for‐Size Syndrome Grade B/C After Simultaneous Splenectomy in Adult Living‐Donor Liver Transplantation

Annals of Gastroenterological Surgery, EarlyView.
In a single‐center cohort of 577 adult LDLT recipients who underwent simultaneous splenectomy, clinically significant SFSS grade B/C (ILTS‐iLDLT‐LTSI 2023) occurred in 18.2% and was associated with inferior graft survival. Multivariate analysis identified MELD ≥ 30, NLR ≥ 4.5, and donor age ≥ 50 years as independent risk factors, which risk rising ...
Kyohei Yugawa, Takeo Toshima, Shinji Itoh, Takashi Motomura, Shohei Yoshiya, Norifumi Iseda, Tomoharu Yoshizumi   +6 more
wiley   +1 more source