Results 11 to 20 of about 16,904 (242)

Application of Box-Behnken Design in the Preparation, Optimization, and In-Vivo Pharmacokinetic Evaluation of Oral Tadalafil-Loaded Niosomal Film

Pharmaceutics, 2023
Benign prostatic hyperplasia (BPH) affects about 90% of men whose ages are over 65. Tadalafil, a selective PDE-5 inhibitor, was approved by FDA for BPH, however, its poor aqueous solubility and bioavailability are considered major drawbacks.
Kawthar K Abla, A. Mneimneh, Ahmed N Allam, Mohammed M. Mehanna   +3 more
semanticscholar   +1 more source

Comparative study between Tamsulosin, Silodosin and Tadalafil as a medical expulsive therapy for lower ureteral stones.

Archivio Italiano di Urologia e Andrologia, 2023
OBJECTIVE To compare the efficacy of Tamsulosin, Silodosin and Tadalafil as a medical expulsive therapy for treatment of distal ureteral calculi. PATIENTS AND METHODS Over a period of 6 months (January 2022 to June 2022) this prospective randomized study
M. A. Abdelaal, Eman M. El-dydamony
semanticscholar   +1 more source

Proniosomal Gel-Loaded Phosphodiesterase Inhibitors (Sildenafil, Vardenafil, and Tadalafil): Prospects for Topical Penile Therapy of Tadalafil for Treatment of Erectile Dysfunction

Gels, 2023
Oral phosphodiesterase inhibitors have emerged as a game changer for the treatment of erectile dysfunction (ED) since attaining FDA approval for its first member, sildenafil, in 1998.
S. A. Mohamed, R. Rofaeil, Hesham Salem, Mahmoud Elrehany, Y. Asiri, Adel Al Fatease, Hamdy Abdelkader   +6 more
semanticscholar   +1 more source

Tamsulosin vs. Tadalafil as medical expulsive therapy for distal ureteral stones: a systematic review and meta-analysis

International Brazilian Journal of Urology, 2023
Purpose: Medical expulsive therapy (MET) is recommended for distal ureteral stones from 5 to 10 mm. The best drug for MET is still uncertain. In this review, we aim to compare the effectiveness of tadalafil and tamsulosin for distal ureteral stones from ...
Mikhael Belkovsky, G. V. Zogaib, C. Passerotti, Everson Luiz de Almeida Artifon, J. Otoch, J. D. da Cruz   +5 more
semanticscholar   +1 more source

Portopulmonary hypertension practice patterns after liver transplantation

Liver Transplantation, EarlyView., 2022
Abstract Portopulmonary hypertension (POPH) is a type of pulmonary arterial hypertension occurring exclusively in those with portal hypertensive liver disease. Liver transplantation (LT) can significantly improve outcomes. Current guidelines counsel against immediate adjustments to targeted therapy after LT and suggest routine echocardiography as ...
Arun Jose, Elizabeth J. Kopras, Shimul A. Shah, Jean M. Elwing   +3 more
wiley   +1 more source

Effects of tadalafil on sexual behavior of male rats induced by chronic unpredictable mild stress

Sexual Medicine, 2023
Background Few studies have investigated psychogenic sexual dysfunction including psychogenic erectile dysfunction (pED); the effect of tadalafil on sexual behavior of male rats induced by chronic unpredictable mild stress (CUMS) remains unclear. Aim The
Heng Wang, Xueping Liu, Ziheng Zhang, Ziyang Han, Yongsheng Jiang, Yu-Ting Qiao, Tao Liu, Jianhuai Chen, Yun Chen   +8 more
semanticscholar   +1 more source

The PASTIS trial: Testing tadalafil for possible use in vascular cognitive impairment

Alzheimer's & Dementia, 2022
There are few randomized clinical trials in vascular cognitive impairment (VCI). This trial tested the hypothesis that the PDE5 inhibitor tadalafil, a widely used vasodilator, increases cerebral blood flow (CBF) in older people with symptomatic small ...
M. Pauls, L. Binnie, P. Benjamin, S. Betteridge, B. Clarke, Mohani-Preet K Dhillon, R. Ghatala, Fearghal A. H. Hainsworth, F. Howe, U. Khan, C. Kruuse, J. Madigan, B. Moynihan, B. Patel, Anthony C. Pereira, E. Rostrup, A. Shtaya, Catherine A. Spilling, S. Trippier, Rebecca Williams, R. Young, T. Barrick, J. Isaacs, A. Hainsworth   +23 more
semanticscholar   +1 more source

Daily low-dose tadalafil may reduce the penile curvature progression rate in patients with acute Peyronie’s disease: a retrospective comparative analysis

International journal of impotence research, 2022
The aim of this study was to evaluate the clinical outcomes of patients in acute phase of Peyronie’s disease (PD) treated with daily low-dose of Tadalafil.
Lorenzo Spirito, C. Manfredi, Roberto la Rocca, L. Napolitano, Antonio di Girolamo, M. Capece, F. Trama, C. Sciorio, I. Sokolakis, M. Creta, D. Arcaniolo   +10 more
semanticscholar   +1 more source

Tadalafil Nanoemulsion Mists for Treatment of Pediatric Pulmonary Hypertension via Nebulization

Pharmaceutics, 2022
Oral tadalafil (TD) proved promising in treating pediatric pulmonary arterial hypertension (PAH). However, to ensure higher efficacy and reduce the systemic side effects, targeted delivery to the lungs through nebulization was proposed as an alternative ...
Bassant Elbardisy, N. Boraie, S. Galal
semanticscholar   +1 more source

Effects of furosemide and tadalafil in both conventional and nanoforms against adenine-induced chronic renal failure in rats

European Journal of Medical Research, 2022
Background Chronic renal failure (CRF) is a progressive loss of renal function that lead to reduced sodium filtration and inappropriate suppression of tubular reabsorption that ultimately leads to volume expansion.
M. Hamdy, M. Abdel-Rahman, D. Badary, Mahmoud S Sabra   +3 more
semanticscholar   +1 more source