Results 31 to 40 of about 15,576 (197)
Therapeutic Advances in Respiratory Disease, 2013 The purpose of this review is to evaluate the use of tadalafil as monotherapy and in combination regimens for the treatment of pulmonary arterial hypertension (PAH).
Dioma U. Udeoji, Ernst R. Schwarz
doaj +1 more source
Sexual Medicine, 2019 Objective: To assess whether tadalafil improves endothelial dysfunction(EnD) in a placebo-controlled randomized-control trial. Methods: Erectile dysfunction and EnD were assessed by the International Index of Erectile Function (IIEF-5) and flow-mediated ...
Smita Pattanaik, DM +4 more
doaj +1 more source
The role of endothelin-1 in pulmonary arterial hypertension. [PDF]
, 2014 Pulmonary arterial hypertension (PAH) is a rare but debilitating disease, which if left untreated rapidly progresses to right ventricular failure and eventually death. In the quest to understand the pathogenesis of this disease differences in the profile,
Chester, AH, Yacoub, MH
core +1 more source
The phosphodiesterase 5 inhibitor sildenafil decreases the proinflammatory chemokine IL-8 in diabetic cardiomyopathy: in vivo and in vitro evidence [PDF]
, 2019 Purpose: Interleukin (IL)-8 is a proinflammatory C-X-C chemokine involved in inflammation underling cardiac diseases, primary or in comorbid condition, such diabetic cardiomyopathy (DCM).
Antinozzi, C. +10 more
core +1 more source
Evaluation of the effect of administration of Tadalafil on Gentamicin-induced nephrotoxicity in rats [PDF]
Egyptian Journal of Medical Research, 2022 Background: Gentamicin (GNT) is a highly effective aminoglycoside antibiotic that is commonly used to treat life-threatening bacterial infections.
Ekhlas Mohammed +3 more
doaj +1 more source
Pharmacology Research & Perspectives, 2021 The COVID‐19 pandemic has forced clinical studies to accommodate imposed limitations. In this study, the bioequivalence part could not be conducted as planned.
Dénes Csonka +6 more
doaj +1 more source
New approaches of morfofunktional pharmacological correction of violations of cardiovascular system in experimental preeclampsia [PDF]
, 2016 Experimental Modeling ADMA-like preeclampsia administration to rats was performed by Nnitro-L-arginine methyl ester, from 14 to 20 days of pregnancy.
Gureev, V. V.
core +2 more sources
BMC Chemistry, 2022 Entadfi™ is a recently FDA approved pharmaceutical combination capsule of finasteride and tadalafil. It was prescribed for the treatment of urinary tract disorders caused by benign prostatic hyperplasia in men.
Ahmed H. Abdelazim, Sherif Ramzy
doaj +1 more source
New insights into the pathogenesis and treatment of non-viral hepatocellular carcinoma: a balancing act between immunosuppression and immunosurveillance. [PDF]
, 2018 Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths worldwide. HCC initiates as a consequence of chronic liver damage and inflammation caused by hepatitis B and C virus infections, excessive alcohol consumption, or non ...
Karin, Michael
core +1 more source
Scientific ReportsThe joint impact of tadalafil (Cilais) as a pharmaceutical residue and microplastics on fish is not well comprehended. The current study examined haematological, biochemical, and antioxidant parameters, along with immunohistochemical and histological ...
Mahmoud S. Sabra +3 more
doaj +1 more source