Results 31 to 40 of about 16,904 (242)

Management of erectile dysfunction post-radical prostatectomy [PDF]

, 2014
© 2015 Saleh et al.Radical prostatectomy is a commonly performed procedure for the treatment of localized prostate cancer. One of the long-term complications is erectile dysfunction.
Abboudi, H, Ghazal-Aswad, M, Mayer, EK, Saleh, A, Vale, JA   +4 more
core   +1 more source

Tadalafil monotherapy in management of chronic prostatitis/chronic pelvic pain syndrome: a randomized double-blind placebo controlled clinical trial

World journal of urology, 2022
In this placebo-controlled trial, we aimed to evaluate the clinical results of using PDE-5 inhibitor, tadalafil 5 mg OD, for management of CP/CPPS. 140 patients ≤ 45 years old with moderate/severe CP/CPPS associated with ED (IIEF-5 
A. Tawfik, M. Radwan, Mohammed Abdulmonem, Mohammed Abo-Elenen, S. Elgamal, Mohammed O. Aboufarha   +5 more
semanticscholar   +1 more source

Erectile dysfunction and its management in patients with diabetes mellitus [PDF]

, 2015
Diabetes can be described as a syndrome of multiple closely related conditions induced by a chronic state of hyperglycaemia resulting from defective insulin secretion, insulin action or both.
DEFEUDIS, GIUSEPPE, Di Emidio, Chiara, GIANFRILLI, DANIELE, LENZI, Andrea, Palermo, Andrea, POFI, RICCARDO, Pozzilli, Paolo, Tuccinardi, Dario   +7 more
core   +1 more source

Analysis of integrated clinical safety data of tadalafil in patients receiving concomitant antihypertensive medications

The Journal of Clinical Hypertension, 2022
This pooled safety analysis assessed the incidence of hypotension‐related treatment‐emergent adverse events (TEAEs) and major adverse cardiovascular events (MACEs) in patients with concomitant use of tadalafil and antihypertensive medications.
R. Kloner, J. Kostis, T. McGraw, Chunfu Qiu, A. Gupta   +4 more
semanticscholar   +1 more source

THE EFFECT OF COMBINED α1-ADRENERGIC BLOCKERS AND PDE-5 INHIBITORS THERAPY ON IPSS, IIEF-5, QMAX AND PVR PATIENTS BPH WITH LUTS AND ERECTILE DYSFUNCTION

Jurnal Urologi Indonesia, 2017
Purpose: Assess the efficacy of combined α1-adrenergic blocker (tamsulosin 0,4 mg) and PDE5 inhibitor (tadalafil 5 mg) therapy compared to tadalafil or tamsulosin alone in treating patient BPH with LUTS and ED.
Muhammad Ridha, Sunaryo Hardjowijoto, Johan Renaldo   +2 more
doaj   +1 more source

Tadalafil modulates aromatase activity and androgen receptor expression in a human osteoblastic cell in vitro model [PDF]

, 2016
Purpose Phosphodiesterase type-5 inhibitor (PDE5i) tadalafil administration in men with erectile dysfunction is associated with increased testosterone/estradiol ratio, leading to hypothesize a potential increased effect of androgen action on target ...
Aversa, Antonio, Bimonte, V. M., Fittipaldi, Simona, Francomano, Davide, Greco, E. A., Lenzi, Andrea, Migliaccio, S., Papa, V., Wannenes, F.   +8 more
core   +1 more source

Meta-Analysis of the Long-Term Efficacy and Tolerance of Tadalafil Daily Compared With Tadalafil On-Demand in Treating Men With Erectile Dysfunction

Sexual Medicine, 2019
Background: Erectile dysfunction (ED) is highly prevalent in aging men. Tadalafil daily and on-demand are widely used for the treatment of ED. Aim: We performed a meta-analysis to evaluate the efficacy and safety of tadalafil daily compared with ...
Zhongbao Zhou, MM, Hongyan Chen, MM, Jitao Wu, MD, Jipeng Wang, MM, Xuebao Zhang, MM, Jiajia Ma, MM, Yuanshan Cui, MD   +6 more
doaj   +1 more source

Testosterone insulin-like effects: an in vitro study on the short-term metabolic effects of testosterone in human skeletal muscle cells [PDF]

, 2017
Testosterone by promoting different metabolic pathways contributes to short-term homeostasis of skeletal muscle, the largest insulin-sensitive tissue and the primary site for insulin-stimulated glucose utilization.
Antinozzi, Cristina, Corinaldesi, C, Crescioli, C, Di Luigi, L., Lenzi, Andrea, Marampon, F, Sgro', PAOLO GIUSEPPE MARIA, Vannelli, G. B, Vicini, Elena   +8 more
core   +2 more sources

Identifcation of small molecule enzyme inhibitors as broad-spectrum anthelmintics [PDF]

, 2019
Targeting chokepoint enzymes in metabolic pathways has led to new drugs for cancers, autoimmune disorders and infectious diseases. This is also a cornerstone approach for discovery and development of anthelmintics against nematode and flatworm parasites.
Aroian, Raffi V., Brindley, Paul J., Bulman, Christina A., Elfawal, Mostafa A., Helander, Jon, Janetka, James W., Mitreva, Makedonka, Rosa, Bruce A., Sakanari, Judy, Tyagi, Rahul, Wildman, Scott A.   +10 more
core   +3 more sources

Tadalafil for veterans with chronic obstructive pulmonary disease—pulmonary hypertension: A multicenter, placebo‐controlled randomized trial

Pulmonary Circulation, 2022
Treating Veterans with chronic obstructive pulmonary disease complicated by pulmonary hypertension (COPD‐PH) using phosphodiesterase type‐5 inhibitor pharmacotherapy is common, but efficacy data are lacking. To address this further, patients with COPD‐PH
B. Maron, G. Choudhary, R. Goldstein, E. Garshick, M. Jankowich, Troo J S Tucker, Kathleen LaCerda, Brack Hattler, E. Dempsey, R. Sadikot, S. Shapiro, S. Rounds, Ronald H. Goldstein   +12 more
semanticscholar   +1 more source