Results 91 to 100 of about 10,207 (224)

Immunophenotypic, Genetic, and Clinical Features Associated With RUNX1 Mutation in Acute Leukemias and Chronic Myeloid Neoplasms

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction RUNX1 is a commonly mutated transcriptional regulator of hematopoiesis in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). Mutated RUNX1 (mRUNX1) may associate with cross‐lineage immunophenotypic aberrancy, presenting potential complications for blast lineage assignment at diagnosis. Methods Clinical and laboratory
Yi Han Xia, Eric McGinnis
wiley   +1 more source

Characterisation of HIV‐1 Gag Cytotoxic T‐Lymphocyte Epitopes in the Southern African Region—A Systematic Review

Immunology, EarlyView.
Distribution of studies on HIV‐1 Gag cytotoxic T‐lymphocyte epitopes in the southern African region showing that the majority of studies (58.44%) were conducted in South Africa, followed by Botswana (15.58%), Zambia (10.39%), Malawi (7.79%), Zimbabwe (6.49%), and Angola (1.30%).
Tumelo L. Fortuin, Paballo Nkone, Shayne Loubser, Caroline T. Tiemessen, Simnikiwe H. Mayaphi   +4 more
wiley   +1 more source

Role of the tomato MARS1/ROUGH gene encoding a LYSINE‐SPECIFIC HISTONE DEMETHYLASE 1 in adventitious root and fruit skin formation

Journal of Integrative Plant Biology, EarlyView.
The tomato mars1/rough mutant displays enhanced root regeneration and rough fruits due to ectopic cell proliferation. The causal gene encodes a lysine‐specific histone demethylase that normally maintains gene silencing. Its loss alters histone methylation, upregulating several genes, including those B‐type cyclins involved in tissue‐specific cellular ...
Eduardo Larriba, Cécile Bres, Aurora Alaguero‐Cordovilla, Riyazuddin Riyazuddin, Qingyi Wang, Johann Petit, Jean‐Philippe Mauxion, Lara Caballero, David Latrasse, Bénédicte Bakan, Rim Brik‐Chaouche, David Esteve‐Bruna, Moussa Benhamed, Christophe Rothan, José Manuel Pérez‐Pérez   +14 more
wiley   +1 more source

Long‐Term Associations Between Energy Expenditure and CGM‐Derived Metrics in Adults With Type 1 Diabetes: A Retrospective Analysis of the Syntactiq Cockpit Database

Diabetes, Obesity and Metabolism, EarlyView.
Katharina Bünzel, Sabrina Sanfilippo, Janis Schierbauer, Lukas Schuster, Harald Sourij, Martin Tauschmann, Ulrike Leb‐Stöger, Andreas Seemann, Gerhard Tschakert, Philipp Birnbaumer, Ali Kapan, Othmar Moser   +11 more
wiley   +1 more source

High‐quality genome of elite peanut cultivar ZH05 reveals subgenome asymmetry, pan‐genome diversity, and breeding insights

Journal of Integrative Plant Biology, EarlyView.
A high‐quality reference genome for the elite peanut cultivar Zhonghua No. 5 revealed differing evolutionary paths between the two peanut subgenomes. SubA has higher overall gene expression and more open chromatin, whereas SubB has stronger structural organization, higher DNA methylation, and greater adaptive diversity associated with peanut evolution ...
Taihua Yang, Nian Liu, Li Huang, Jianbin Guo, Xiaomeng Xue, Mingjun Wang, Xiaohan Zhang, Chengtao Quan, Enyou Feng, Jiazhuang Tan, Zhenzhen Zhang, Yu You, Youlin Xia, Dongxin Huai, Yuning Chen, Liyin Yan, Kede Liu, Huifang Jiang, Yong Lei, Boshou Liao   +19 more
wiley   +1 more source

How LLMs might think

Mind &Language, EarlyView.
Do large language models (“LLMs”) think? Daniel Stoljar and Zhihe Vincent Zhang have recently developed an argument from rationality for the claim that LLMs do not think. We contend, however, that the argument from rationality not only falters, but leaves open an intriguing possibility: that LLMs engage only in arational, associative forms of thinking ...
Joseph Gottlieb, Ethan Kemp, Matthew Trager   +2 more
wiley   +1 more source

A multi-tissue and -breed catalogue of chromatin conformations and their implications in gene regulation in pigs

BMC Genomics
Background Topologically associating domains (TADs) are functional units that organize chromosomes into 3D structures of interacting chromatin, and play a crucial role in regulating gene expression by constraining enhancer-promoter contacts.
Hongwei Yin, Qianyi Zhao, Liu Yang, Guoqiang Yi, Wenye Yao, Lingzhao Fang, Lijing Bai   +6 more
doaj   +1 more source

A ‘TAD’ easier to calculate! [PDF]

The Annals of The Royal College of Surgeons of England, 2014
openaire   +2 more sources

The 3D genome of Gigaspora margarita unveils stable chromatin and nucleolar organization and symbiont‐dependent genome dynamics

New Phytologist, EarlyView.
Summary Arbuscular mycorrhizal fungi (AMF) are widespread plant symbionts that enhance nutrient acquisition and influence ecosystem productivity. Previous chromosome‐level assemblies of the model species Rhizophagus irregularis revealed a two‐compartment genome architecture (active A and repressed B chromatin compartments), yet its conservation across ...
Ken Mugambi, Jordana Oliveira, Franco Magurno, Alessandra Salvioli di Fossalunga, Mara Novero, Luisa Lanfranco, Stefano Ghignone, Gökalp Yildirir, Yan Wang, Paola Bonfante, Nicolas Corradi   +10 more
wiley   +1 more source

The Role of Fat‐Free Mass in Weight‐Related Complications: A Rapid Review and Meta‐Analysis

Obesity Reviews, EarlyView.
ABSTRACT Background This review synthesized evidence on the association between fat‐free mass (FFM) metrics and weight‐related metabolic complications in adults with overweight or obesity. Methods A systematic search of Medline, Embase, Web of Science, and Google Scholar (inception to October 2024) identified 32 observational studies involving 138,935 ...
Tadesse Asmamaw Dejenie, Paul P. Fahey, Haider Mannan, Mohammad Ariya, Evan Atlantis   +4 more
wiley   +1 more source