Results 71 to 80 of about 10,149 (228)

Current situation, trends, and challenges navigating temporary anchorage devices usage among orthodontists in China: a comprehensive multi-center survey

open access: yesBMC Oral Health
Background The temporary anchorage devices (TADs) are presently a viable and popular treatment option for orthodontics all over the world. However, there is a lack of investigation and research on its application among orthodontists in China.
Zining Chen   +5 more
doaj   +1 more source

Topologically Associated Domains Delineate Susceptibility to Somatic Hypermutation

open access: yesCell Reports, 2019
Summary: Somatic hypermutation (SHM) introduces point mutations into immunoglobulin (Ig) genes but also causes mutations in other parts of the genome.
Filip Senigl   +13 more
doaj   +1 more source

Ashwagandha: Is It Safe? Part 1: A Regulatory Review

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Over the last decade, ashwagandha (Withania somnifera (L.) Dunal, AS) has been brought under increasing scrutiny by EU regulators regarding its safety for the use in food supplements, culminating in a recent recommendation for an Article 8 procedure according to Regulation (EC) No. 1925/2006 in the European Union (EU).
T. Brendler   +5 more
wiley   +1 more source

Greenway development and gentrification

open access: yesSouthern Economic Journal, EarlyView.
Abstract This paper presents research on expanding access to green spaces in developed areas. Critics claim greenway projects lead to gentrification by increasing the demand for housing and pushing out residents in nearby neighborhoods. We look for evidence of this phenomenon using a sorting model and panel data on aggregate populations in Atlanta ...
Jarron VanCeylon, Richard T. Melstrom
wiley   +1 more source

Postmortem submergence interval (PMSI) and human decomposition in anthropogenically constructed aqueous environments (pools, bathtubs, hot tubs, and spas)

open access: yesJournal of Forensic Sciences, EarlyView.
Abstract Postmortem decomposition changes of bodies in aquatic environments may offer valuable insights into the postmortem submergence interval (PMSI) for medicolegal death investigators. However, the effects of immersion on the onset of such changes are poorly understood.
Vienna C. Lam   +4 more
wiley   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus   +5 more
wiley   +1 more source

Prevalence and risk factors of thoracic aortic dilatation detected incidentally in adjuvant radiotherapy planning CT scans in patients with breast cancer

open access: yesScientific Reports
Thoracic aortic dilatations (TADs) are commonly detected incidentally. A TAD may develop into aortic aneurysm and subsequently lead to aortic dissection, a highly lethal condition.
Aada Lattu   +7 more
doaj   +1 more source

Influence of mobility and work–family conflict on U.S. military spouse employment

open access: yesFamily Relations, EarlyView.
ABSTRACT Objective This study longitudinally assessed how mobility across geographic regions and work–family conflict influenced spouse employment trajectories and perceptions of career hindrance. Background The unemployment rate for U.S. military spouses has remained 21% since 2015 with specific aspects of military life, such as moving, reported as ...
Kelly A. Woodall   +19 more
wiley   +1 more source

Quantitative analysis of DNA‐GATA1 binding alterations linked to hematopoietic disorders

open access: yesThe FEBS Journal, EarlyView.
Native holdup allows the quantitative determination of affinities between full‐length transcription factors and DNA. Mutations in either the protein or the DNA can modulate binding strength, which can be precisely quantified using this approach. Applied to GATA1, it revealed mutations that alter DNA binding.
Boglarka Zambo   +6 more
wiley   +1 more source

RAB4A acts as a negative feedback regulator of extracellular vesicle secretion during TGF‐β signaling

open access: yesThe FEBS Journal, EarlyView.
TGF‐β signaling regulates extracellular vesicle (EV) release in cancer cells by modulating the expression and activity of genes associated with EV biogenesis. The TGF‐β‐induced upregulation of RAB4A expression facilitates fast endosomal recycling, a process that limits the fusion of multivesicular bodies with the plasma membrane and EV secretion. Hence,
Dorival Mendes Rodrigues‐Junior   +5 more
wiley   +1 more source

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