ApoJ regulates endothelial lipase activity and stability
Abstract Endothelial lipase (EL) is a key regulator of high‐density lipoprotein (HDL) metabolism. Many aspects of EL function remain incompletely understood due to challenges in purifying active EL. This study identifies apolipoprotein J (ApoJ) as a novel chaperone for EL, crucial for its solubility and activity.
Uriel L. Jean‐Baptiste +5 more
wiley +1 more source
Unlocking photochemical tunability in functionalised bridged-isoindigo molecular motors. [PDF]
van Beek CLF +3 more
europepmc +1 more source
ABSTRACT Anaerobic ammonium‐oxidizing (anammox) bacteria employ a unique, hydrazine‐based pathway to obtain energy from nitrite and ammonium. These organisms possess distinct Rieske/cytochrome b complexes whose precise role in anammox metabolism remains unclear, but which have been proposed to include the generation of NAD(P)H.
David Hauser +4 more
wiley +1 more source
A model of β-adrenergic stimulation in human ventricular cells for tissue-scale simulations of sympathetically modulated tachycardias. [PDF]
Zhang K +3 more
europepmc +1 more source
Supramolecular Assemblies of Self‐Immolative Janus Dendrimers With Rapid Photodegradation Response
Self‐immolative Janus dendrimers assemble into spherical nanoparticles with solid cores. Upon irradiation, rapid end‐to‐end depolymerization triggers a unique degradation pathway from spheres to crescents within minutes, enabling on‐demand release of encapsulated cargo.
Chuanfeng Li +3 more
wiley +1 more source
Solid-State NMR Spectroscopy Investigation of Structural Changes of Mechanically Strained Mouse Tail Tendons. [PDF]
Kress T, Duer MJ.
europepmc +1 more source
Weibull‐Neural Network Framework for Wind Turbine Lifetime Monitoring and Disturbance Identification
ABSTRACT Wind turbines are vital for sustainable energy, yet their reliability under diverse operational and environmental conditions remains a challenge, often leading to costly failures. This study presents a novel Weibull‐Neural Network Framework to enhance wind turbine lifetime monitoring by estimating reliability (R(t)) and mean residual life (MRL)
Fatemeh Kiadaliry +2 more
wiley +1 more source
Genomic and Functional Characterization of Lytic <i>Tlsvirus</i> Bacteriophages Targeting <i>Salmonella</i> Infantis Isolated from Poultry Farms in Ecuador. [PDF]
Sevilla-Navarro S +5 more
europepmc +1 more source
Molecular structure and nickel‐binding capacity of Proteus mirabilis UreE
This study presents a 2.0 Å resolution crystal structure and determined the nickel‐binding capacity of the P. mirabilis nickel chaperone UreE. UreE is essential for the delivery of nickel to the metalloenzyme urease, which is key for the ability of P. mirabilis to cause urinary‐tract infections.UreE is a nickel chaperone that is required for the safe ...
Jiayi Pan +4 more
wiley +1 more source
TPTE, a testis-specific PTEN family member, drives spermatogenesis via PI(4,5)P<sub>2</sub> synthesis. [PDF]
Chen X +14 more
europepmc +1 more source

