Results 21 to 30 of about 904,909 (193)
Hematology, Transfusion and Cell Therapy, 2023 Objetivo: Relatar um estudo familial de um caso de coeranças de três mutações nos genes que expressam as cadeias alfa e beta da hemoglobina (Hb), o qual foi recebido e diagnosticado pelo Laboratório de Genética e Biologia Molecular (LGBM) da UFMS/CPTL ...
BBV Marques +9 more
doaj +1 more source
Impact of the preparation method of red cell concentrates on transfusion indices in thalassemia patients: A randomized crossover clinical trial. [PDF]
Transfusion, 2021 Abstract Background The average hemoglobin content of red cell concentrates (RCC) varies depending on the method of preparation. Surprisingly less data are available concerning the clinical impact of those differences. Study Design and Methods The effects of two types of RCC (RCC‐A, RCC‐B) on transfusion regime were compared in a non‐blinded ...
Gamberini MR +15 more
europepmc +2 more sources
Hematology, Transfusion and Cell Therapy, 2023 Objetivos: Realizar a caracterização de mutações de beta talassemia em pessoas com doença falciforme (Hb S/Beta-talassemia). Material e métodos: No período de cinco anos, 29 amostras de pessoas com diagnóstico molecular inconclusivo para a doença ...
JJR Silva +9 more
doaj +1 more source
Hematology, Transfusion and Cell Therapy, 2023 Objetivo: Avaliar a influência da alfa talassemia em portadores da hemoglobina S (Hb AS) e determinar as concentrações de hemoglobina S (Hb S) como suporte de diagnóstico laboratorial.
IS Dias +9 more
doaj +1 more source
Talassemia beta maior: uma nova era Beta thalassaemia major: a new era
Revista Brasileira de Hematologia e Hemoterapia, 2008 Rodolfo D. Cançado
doaj +2 more sources
Cancer, Volume 129, Issue 1, Page 107-117, 1 January 2023., 2023 Abstract Background The correlation between thalassemia and malignancies other than hepatocellular carcinoma (HCC) and the possible relationship between other hemoglobinopathies and tumor risk have been poorly evaluated. Methods Eight Italian specialized centers evaluated the incidence of malignant neoplasms in hemoglobinopathies as well as their sites
Raffaella Origa +20 more
wiley +1 more source
Hematology, Transfusion and Cell Therapy, 2023 Objetivo: O estudo se refere ao relato de caso de uma criança com dupla heterozigose de beta talassemia, sendo portanto, o primeiro registro da interação entre as mutações HBB:c.48G>A (Códon 15) e HBB:c.137C>T (Códon 87). Materiais e métodos: Uma amostra
KC Piva +7 more
doaj +1 more source
Long-term outcomes of avascular necrosis in sickle cell disease using joint-specific patient-reported outcome measures: Results from a multicentre study. [PDF]
Br J HaematolSummary Avascular necrosis (AVN) is a prevalent and progressive complication in young patients with sickle cell disease (SCD), but no study evaluated the long‐term subjective and objective outcome measures. Oxford hip score (OHS) and Oxford shoulder scores (OSS) are validated joint‐specific patient‐reported outcome measures (PROMs). In this prospective
Casale M +9 more
europepmc +2 more sources
Hematology, Transfusion and Cell Therapy, 2023 Objetivo: Demonstrar a relevância do diagnóstico molecular na identificação de heterozigoto composto para beta talassemias HBB:c.118C>T (CD39) e HBB:c.-138C>T (-88C>T) em recém-nascido da triagem neonatal.
VS Ramos +8 more
doaj +1 more source
Selecting β‐thalassemia Patients for Gene Therapy: A Decision‐making Algorithm
HemaSphere, Volume 5, Issue 5, May 2021., 2021 This expert opinion originally developed by a panel of the Italian Society of Thalassemias and Hemoglobinopathies (SITE), reviewed and adopted by the European Hematology Association (EHA) through the EHA Scientific Working Group on Red Cells and Iron, has been developed as priority decision‐making algorithm on evidence and consensus with the aim to ...
Donatella Baronciani +13 more
wiley +1 more source