Results 11 to 20 of about 723 (163)

Incidence of cancer and related deaths in hemoglobinopathies: A follow‐up of 4631 patients between 1970 and 2021

open access: yesCancer, Volume 129, Issue 1, Page 107-117, 1 January 2023., 2023
Abstract Background The correlation between thalassemia and malignancies other than hepatocellular carcinoma (HCC) and the possible relationship between other hemoglobinopathies and tumor risk have been poorly evaluated. Methods Eight Italian specialized centers evaluated the incidence of malignant neoplasms in hemoglobinopathies as well as their sites
Raffaella Origa   +20 more
wiley   +1 more source

Thalassaemia is paradoxically associated with a reduced risk of in‐hospital complications and mortality in COVID‐19: Data from an international registry

open access: yesJournal of Cellular and Molecular Medicine, Volume 26, Issue 9, Page 2520-2528, May 2022., 2022
Abstract Although numerous patient‐specific co‐factors have been shown to be associated with worse outcomes in COVID‐19, the prognostic value of thalassaemic syndromes in COVID‐19 patients remains poorly understood. We studied the outcomes of 137 COVID‐19 patients with a history of transfusion‐dependent thalassaemia (TDT) and transfusion independent ...
Ibrahim El‐Battrawy   +49 more
wiley   +1 more source

ANEMIAS MICROCÍTICAS-HIPOCRÔMICAS: ANÁLISE ETIOLÓGICA EM 8 ANOS DE ATENDIMENTO

open access: yesHematology, Transfusion and Cell Therapy, 2021
Objetivo: Descrição da experiência dos últimos 8 anos de acompanhamento e diagnóstico etiológico das anemias microcíticas-hipocrômicas em serviço médico de hematologia & hemoterapia no interior do estado de São Paulo.
ML Puls, AAL Puls
doaj   +1 more source

ANÁLISE DA HEMATOSCOPIA EM PACIENTES COM ANEMIAS HEMOLÍTICAS EM UM AMBULATÓRIO DE HEMATOLOGIA DE UM HOSPITAL UNIVERSITÁRIO

open access: yesHematology, Transfusion and Cell Therapy, 2023
Introdução/Objetivos: As anemias hemolíticas (AH) são condições que cursam com redução da meia-vida dos eritrócitos. Os diagnósticos etiológicos das AH são diversos e podem ser suspeitados de acordo com alterações hematoscópicas.
FOC Souza   +9 more
doaj   +1 more source

AVALIAÇÃO DO PERFIL DE HBA2 NOS PACIENTES COM DOENÇA FALCIFORME SUBMETIDOS A PESQUISA HEMOGLOBINOPATIAS NO LABORATÓRIO ESCOLA DE ANÁLISES CLÍNICAS DA FACULDADE DE FARMÁCIA (LACFAR)

open access: yesHematology, Transfusion and Cell Therapy, 2023
Os distúrbios da hemoglobina (Hb) são as alterações monogênicas de caráter hereditário mais frequentemente no mundo. Originárias de regiões continentais específicas, hoje podem ser encontradas em diferentes países ao redor do planeta e em altos números ...
GS Ferreira, EA Santos, LS Wermelinger
doaj   +1 more source

Impact of the preparation method of red cell concentrates on transfusion indices in thalassemia patients: A randomized crossover clinical trial

open access: yesTransfusion, Volume 61, Issue 6, Page 1729-1739, June 2021., 2021
Abstract Background The average hemoglobin content of red cell concentrates (RCC) varies depending on the method of preparation. Surprisingly less data are available concerning the clinical impact of those differences. Study Design and Methods The effects of two types of RCC (RCC‐A, RCC‐B) on transfusion regime were compared in a non‐blinded ...
Maria Rita Gamberini   +15 more
wiley   +1 more source

Selecting β‐thalassemia Patients for Gene Therapy: A Decision‐making Algorithm

open access: yesHemaSphere, Volume 5, Issue 5, May 2021., 2021
This expert opinion originally developed by a panel of the Italian Society of Thalassemias and Hemoglobinopathies (SITE), reviewed and adopted by the European Hematology Association (EHA) through the EHA Scientific Working Group on Red Cells and Iron, has been developed as priority decision‐making algorithm on evidence and consensus with the aim to ...
Donatella Baronciani   +13 more
wiley   +1 more source

ANÁLISE MOLECULAR DE 32 CASOS DE DOENÇA DA HB H IDENTIFICADOS NO LABORATÓRIO DE HEMOGLOBINOPATIAS DO HC/UNICAMP (2002-2023)

open access: yesHematology, Transfusion and Cell Therapy, 2023
As talassemias alfa (α) são frequentemente causadas por deleções nos genes da globina α (HBA1 e HBA2), e podem envolver um ou ambos os genes, o que resulta em redução parcial (alelo α+ ou -α) ou supressão total (alelo α0 ou –) da produção das globinas α.
GA Pedroso   +8 more
doaj   +1 more source

5613423 TREATMENT OF ERYTHROID PRECURSOR CELLS FROM β‐THALASSEMIC PATIENTS WITH ISOXAZOLE DERIVATIVES: POTENT INDUCTION OF FETAL HEMOGLOBIN

open access: yes, 2023
HemaSphere, Volume 7, Issue S1, Page 17-17, April 2023.
C.Z. Cristina Zuccato   +9 more
wiley   +1 more source

Dificuldades no diagnóstico laboratorial das hemoglobinopatias Dificulties on the laboratorial diagnosis of hemoglobinopathies

open access: yesRevista Brasileira de Hematologia e Hemoterapia, 2007
Há vários tipos de hemoglobinopatias que são caracterizados por variantes das hemoglobinas anormais (ex: Hb S, Hb C, Hb Instáveis,etc) e por talassemias (ex: tal. alfa, tal.
Paulo Cesar Naoum   +1 more
doaj   +1 more source

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