Results 41 to 50 of about 125,474 (196)

Long-term effectiveness of adjuvant Goserelin in premenopausal women with early breast cancer [PDF]

open access: yes, 2009
BACKGROUND: Systematic reviews have found that luteinizing hormone-releasing hormone (LHRH) agonists are effective in treating premenopausal women with early breast cancer.
Fornander, T   +48 more
core   +2 more sources

Tamoxifen Treatment for Riedel’s Thyroiditis: A Case Report [PDF]

open access: yes, 2023
Riedel's thyroiditis is a rare variant of thyroiditis, and treatment recommendations are based on case reports. This thyroiditis form is considered among immunoglobulin G4-related diseases.
Karakılıç, Ersen   +11 more
core   +1 more source

Tamoxifen and hypercalcaemia

open access: yesAnnals of Oncology, 1993
The present case demonstrates the importance of close observation, also of serum calcium, when initiating tamoxifen therapy, especially in patients with known osseous metastases. Hypercalcaemia should also be considered as a possible cause of CNS symptoms in patients newly started on endocrine treatment.
openaire   +2 more sources

Nano Packaged Diblock and Curcumin: a New Approach Inorder To Drug Resistance in Breast Cancer

open access: yesIranian South Medical Journal, 2017
Background: Breast cancer is one of the causes of mortality in the world. Half of patients with metastatic extend resistance to Tamoxifen and almost all patients eventually become resistant to tamoxifen. Inorder to counteract with the negative effects of
Samira Hajigholami   +1 more
doaj  

Inhibition of long non-coding RNA ROR reverses resistance to Tamoxifen by inducing autophagy in breast cancer

open access: yesTumor Biology, 2017
This study explored the mechanism underlying long non-coding RNA ROR regulating autophagy on Tamoxifen resistance in breast cancer. Cancer tissues and adjacent normal tissues were collected from 74 breast cancer patients.
Yuehua Li   +8 more
doaj   +1 more source

Proliferation and estrogen signaling can distinguish patients at risk for early versus late relapse among estrogen receptor positive breast cancers [PDF]

open access: yes, 2013
Introduction: We examined if a combination of proliferation markers and estrogen receptor (ER) activity could predict early versus late relapses in ER-positive breast cancer and inform the choice and length of adjuvant endocrine therapy.
Luca Gianni   +40 more
core   +2 more sources

miR-449a Suppresses Tamoxifen Resistance in Human Breast Cancer Cells by Targeting ADAM22

open access: yesCellular Physiology and Biochemistry, 2018
Background/Aims: Most of estrogen receptor positive breast cancer patients respond well initially to endocrine therapies, but often develop resistance during treatment with selective estrogen receptor modulators (SERMs) such as tamoxifen.
Jun Li   +5 more
doaj   +1 more source

Tamoxifen reduces silicone implant capsule formation in a mouse model

open access: yesFASEB BioAdvances, 2022
Capsular contracture as a result of the foreign body response (FBR) is a common issue after implant‐based breast reconstruction, affecting up to 20% of patients. New evidence suggests that tamoxifen may mitigate the FBR.
Kevin M. Blum   +4 more
doaj   +1 more source

A potential role for naringenin in reversing tamoxifen resistance in MCF-7 breast cancer cells [PDF]

open access: yes, 2012
Tamoxifen has been used as an effective treatment against breast cancer for over 30 years. However, tamoxifen resistance has become a major hurdle to effective treatment.
Ramos, Joseph   +1 more
core  

Tamoxifen and pregnancy

open access: yesThe Breast, 2004
Women are conventionally advised to stop tamoxifen before attempting pregnancy. The risks of congenital malformations or late teratogenic manifestations in adulthood are unknown. Following an informed discussion about the uncertainties of tamoxifen exposure on pregnancy women should be offered the choice whether to continue or stop tamoxifen before ...
L, Barthelmes, C A, Gateley
openaire   +2 more sources

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