Results 71 to 80 of about 125,474 (196)

Effect of anastrozole on bone mineral density and lipid profiles when used to prevent breast cancer in high risk postmenopausal women [PDF]

, 2012
PhDThe role of aromatase inhibitors (AIs) in breast cancer has expanded since their introduction in the mid-1990s. They are superior to tamoxifen in the treatment of postmenopausal women with oestrogen dependant tumours in the metastatic, neoadjuvant ...
Singh, Shalini
core   +2 more sources

Variation in human gut microbiota impacts tamoxifen pharmacokinetics

mBio
Tamoxifen is the most prescribed drug used to prevent breast cancer recurrence, but patients show variable responses to tamoxifen. Such differential inter-individual response has a significant socioeconomic impact as one in eight women will develop ...
Yasmine Alam, Sheron Hakopian, Lizett Ortiz de Ora, Ian Tamburini, Julio Avelar-Barragan, Sunhee Jung, Zane Long, Alina Chao, Katrine Whiteson, Cholsoon Jang, Elizabeth Bess   +10 more
doaj   +1 more source

Increased STAT1 signaling in endocrine-resistant breast cancer [PDF]

, 2014
Funding: China Scholarship Council, University of Edinburgh, Scottish Funding Council and Breakthrough Breast Cancer.Proteomic profiling of the estrogen/tamoxifen-sensitive MCF-7 cell line and its partially sensitive (MCF-7/LCC1) and fully resistant (MCF-
Thomas Jeremy S., Faratian Dana, Huang Rui, Sims Andrew H., Dana Faratian (171110), Simon P. Langdon, Danielle Wilson (550968), David J. Harrison (171106), Jeremy S. Thomas, Dana Faratian, Rui Huang, Wilson Danielle, Harrison David J., David J. Harrison, Danielle Wilson, Simon P Langdon, Thomas, Jeremy S, Sims, Andrew H, Andrew H. Sims (108040), Harrison, David J, Rui Huang (141490), Huang, Rui, Simon P. Langdon (207293), Wilson, Danielle, David J Harrison, Thomas, Jeremy, Langdon Simon P., Faratian, Dana, Andrew H. Sims, Andrew H Sims, Jeremy S Thomas, Jeremy S. Thomas (550969), Langdon, Simon P, Harrison, David J; id_orcid   +33 more
core   +2 more sources

Tamoxifen Use Correlates with Increased Risk of the First Episode of Ischemic Cerebrovascular Disease in Older Women with Breast Cancer: A Case-Control Study in Taiwan

Frontiers in Pharmacology, 2017
Background and Objectives: There are inconsistent results about the association between ischemic cerebrovascular disease and tamoxifen use in women with breast cancer.
Shih-Wei Lai, Shih-Wei Lai, Cheng-Li Lin, Cheng-Li Lin, Kuan-Fu Liao, Kuan-Fu Liao   +5 more
doaj   +1 more source

Effects of Tamoxifen on Morphological and Ultrastructural Aspects of Developing Hippocampus of Rat [PDF]

Background: Tamoxifen treatment induced cell death in the hippocampus formation of the prenatal and postnatal rat. The present study delineates the effect of tamoxifen on developing hippocampus in prenatal, postnatal and full term neonate rats received
کردستانی شرق, بهاره, نوبخت, ملیحه, نجف زاده, نوروز   +2 more
core  

Menopausal hot flushes after breast cancer [PDF]

, 2009
The study aimed to improve understanding of the natural history and impact of hot flushes after breast cancer.Data were collected from women participating in an RCT of relaxation to reduce the incidence of flushes from breast cancer follow-up clinics ...
Fenlon, D.R., Corner, J.L., Haviland, J., Deborah Fenlon   +3 more
core   +1 more source

Flap perfusion and tamoxifen.

, 2019
Fig 5A: Flap perfusion assessed by ingress and tamoxifen. Fig 5B: Flap perfusion assessed by ingress rate and tamoxifen.
Delphine Sebbag (6876410), Noémie Girard (6876404), Caroline Malhaire (6876407), Aurélie Roulot (4521223), Benoît Couturaud (6876416), Anne Sabaila (6876413), Fabien Reyal (53750), Myriam Delomenie (3141627), Jean-Guillaume Feron (303659)   +8 more
core   +1 more source

¹¹C标记Tamoxifen的制备

四川大学学报. 自然科学版, 2000
报道了N 去甲基 Tamoxifen(N Demethyltamoxifen)和 11C标记Tamoxifen( 11C Tamox ifen)的制备及高效液相色谱 (HPLC)分离分析方法 .先将Tamoxifen柠檬酸盐 (TamoxifenCit rate)转换成无盐Tamoxifen(Tamoxifenfreebase) ,然后与 1 氯乙基 氯甲酸酯 (ACE Cl)反应生成N 去甲基 Tamoxifen .N 去甲基 Tamoxifen与 11CH3I在 1 3 0℃下反应 1 0min ...
刘宁, DING Yu-Shin
doaj  

Pap Smear Results of Women with Breast Cancer Using Tamoxifen Therapy

İstanbul Medical Journal, 2015
Objective: Our aim was to investigate the effect of tamoxifen on cervical smear of patients with breast cancer at our clinic.Methods: The data of patients with breast cancer who had received tamoxifen were analyzed between 2006 and 2014, retrospectively.
Gülsüm Uysal, Sema Sezgin Göksu, Dilek Ünal, Fulya Çağlı, Hatice Akkaya, Hüseyin Aksoy, Yusuf Madendağ, Gökhan Açmaz   +7 more
doaj   +1 more source

Oxidative stress mediates estrogen receptor independent killing and contributes to tamoxifen resistance

, 2016
Tamoxifen is the accepted therapy for patients with estrogen receptor-α (ERα)-positive breast cancer. However, clinical resistance to tamoxifen, as demonstrated by recurrence or progression on therapy, is frequent and precedes death from metastases.
Brindley, David N., Bekele, Raie T., McMullen, Todd, Benesch, Matthew, Venkatraman, Ganesh, Godbout, Roseline, Mi, Si, Curtis, Jonathan M., Mackey, John R., Tang, Xiaoyun, Liu, Rong-Zong   +10 more
core   +1 more source