Results 131 to 140 of about 253,337 (321)

Spatiotemporal Drug Delivery via a Neonatal Spinal Cord ECM Hydrogel for Biomimetic Microenvironment Remodeling After Spinal Cord Injury

Advanced Functional Materials, EarlyView.
A biomimetic hydrogel derived from neonatal spinal cord ECM (DNSCM) delivers LAMB2 protein and ISP peptide to remodel the inhibitory injury microenvironment. The system sustains drug release, upregulates pro‐regenerative LAMB2, downregulates inhibitory CSPG, and promotes axonal regeneration.
Shiyu Fu, Liangchao Du, Runlin Wen, Kai Zhang, Yu Zhou, Wanrong Ma, Zhiquan Yang, Dingyang Liu, Xing Li   +8 more
wiley   +1 more source

Quantification of mixed chimerism allows early therapeutic interventions

Revista Brasileira de Hematologia e Hemoterapia, 2014
Hematopoietic stem cell transplantation is the curative option for patients with myelodysplastic syndrome; however, it requires a long post-transplantation follow-up.
Jóice Merzoni, Gisele Menezes Ewald, Alessandra Aparecida Paz, Liane Esteves Daudt, Luiz Fernando Job Jobim   +4 more
doaj   +1 more source

Sequences flanking the repeat arrays of human minlsatellites: association with tandem and dispersed repeat elements

Nucleic Acids Research, 1989
We present DNA sequences flanking cloned hypervariable human minisatellites. In addition to providing confirmatory evidence that minisatellites cluster with other tandem repeats, these flanking sequences contain a high frequency of interspersed repetitive elements.
Armour John A. L., Wong Zilla, Wilson Victoria, Royle Nicola J., Jeffreys Alec J.   +4 more
openaire   +4 more sources

Packed for Ossification: High‐Density Bioprinting of hPDC Spheroids in HAMA Toward Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
Human periosteum‐derived cell spheroids bioprinted at high density within a hyaluronic acid matrix promote fusion and hypertrophic cartilage formation in vitro. Early encapsulation enhances spheroid interaction and matrix maturation, generating scalable cartilage templates intended for endochondral bone regeneration.
Ane Albillos Sanchez, Maria Paula Marks, Paula Casademunt, Adrián Seijas‐Gamardo, Ioannis Papantoniou, Lorenzo Moroni, Carlos Mota   +6 more
wiley   +1 more source

Genome-Wide Tool for Sensitive de novo Identification and Visualisation of Interspersed and Tandem Repeats

Bioinformatics and Biology Insights
Genomic repeats are functionally ubiquitous structural units found in all genomes. Studying these repeats of different origins is essential for understanding the evolution and adaptation of a given organism.
Ruslan Kalendar, Ulykbek Kairov
doaj   +1 more source

Rational design of alpha-helical tandem repeat proteins with closed architectures

Nature, 2015
Tandem repeat proteins, which are formed by repetition of modular units of protein sequence and structure, play important biological roles as macromolecular binding and scaffolding domains, enzymes, and building blocks for the assembly of fibrous ...
L. Doyle, J. Hallinan, J. Bolduc, F. Parmeggiani, D. Baker, B. Stoddard, P. Bradley   +6 more
semanticscholar   +1 more source

APE-type non-LTR retrotransposons of multicellular organisms encode virus-like 2A oligopeptide sequences, which mediate translational recoding during protein synthesis

, 2013
2A oligopeptide sequences (“2As”) mediate a cotranslational recoding event termed “ribosome skipping.” Previously we demonstrated the activity of 2As (and “2A-like sequences”) within a wide range of animal RNA virus genomes and non-long terminal repeat ...
Sukhodub, Andriy, Ryan, MD, De Felipe, Pablo, Ruan, L, Odon, Valerie Marie Nathalie, de Felipe, P, Sukhodub, A, Luke, Garry Alec, Ruan, Lin, Escuin-Ordinas, H, Roulston, Claire, Odon, V, Ryan, Martin Denis, Brown, JD, Roulston, C, Brown, Jeremy, Luke, GA, Escuin, Helena   +17 more
core   +1 more source

Bioinspired Adaptive Sensors: A Review on Current Developments in Theory and Application

Advanced Materials, EarlyView.
This review comprehensively summarizes the recent progress in the design and fabrication of sensory‐adaptation‐inspired devices and highlights their valuable applications in electronic skin, wearable electronics, and machine vision. The existing challenges and future directions are addressed in aspects such as device performance optimization ...
Guodong Gong, You Zhou, Qingxiu Li, Wenyu Zhao, Sunyingyue Geng, Hangfei Li, Yan‐Bing Leng, Shirui Zhu, Guanglong Ding, Yongbiao Zhai, Ziyu Lv, Ye Zhou, Su‐Ting Han   +12 more
wiley   +1 more source

Condensin Promotes Position Effects within Tandem DNA Repeats via the RITS Complex

Cell Reports, 2016
Summary: Tandem repetitive DNA is highly abundant in eukaryotic genomes and contributes to transcription control and genome stability. However, how the individual sequences within tandem repeats behave remains largely unknown.
Haijin He, Shu Zhang, Danni Wang, Andreas Hochwagen, Fei Li   +4 more
doaj   +1 more source

Short tandem repeat sequences in the genome and their use in a multilocus genotyping system-2

, 2011
Ents, sequential specimens from the same patients and specimens from concurrently infected couples. () MG309 AGT/AAT repeat sequences among selected plasmid clones from two sequential specimens from one patient (no. 198).
Stephanie Taylor (95318), Rebecca Lillis (95319), Liang Ma (37793), Leann Myers (37795), David H Martin (37799), Jørgen S Jensen (37794)   +5 more
core   +1 more source