Results 11 to 20 of about 2,480 (216)

Native functions of short tandem repeats

open access: yeseLife, 2023
Over a third of the human genome is comprised of repetitive sequences, including more than a million short tandem repeats (STRs). While studies of the pathologic consequences of repeat expansions that cause syndromic human diseases are extensive, the ...
Shannon E Wright, Peter K Todd
doaj   +3 more sources

Double String Tandem Repeats

open access: yesAlgorithmica, 2022
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Amihood Amir   +4 more
openaire   +3 more sources

TRDB--The Tandem Repeats Database [PDF]

open access: yesNucleic Acids Research, 2007
Tandem repeats in DNA have been under intensive study for many years, first, as a consequence of their usefulness as genomic markers and DNA fingerprints and more recently as their role in human disease and regulatory processes has become apparent. The Tandem Repeats Database (TRDB) is a public repository of information on tandem repeats in genomic DNA.
Gelfand, Yevgeniy   +2 more
openaire   +3 more sources

Unique Features of Tandem Repeats in Bacteria [PDF]

open access: yesJournal of Bacteriology, 2020
We found an enigmatic group of noncoding satellites in 85 bacterial genomes with a constant repeat size but variable sequence. This pattern of DNA organization is unique and had not been previously described in bacteria. These findings strongly suggest that satellite size in some bacteria is under strong selective constraints and thus that satellites ...
Subirana Torrent, Juan A.   +1 more
openaire   +4 more sources

Evolutionary Study of Protein Short Tandem Repeats in Protein Families

open access: yesBiomolecules, 2023
Tandem repeats in proteins are patterns of residues repeated directly adjacent to each other. The evolution of these repeats can be assessed by using groups of homologous sequences, which can help pointing to events of unit duplication or deletion.
Pablo Mier, Miguel A. Andrade-Navarro
doaj   +1 more source

FISH landmarks reflecting meiotic recombination and structural alterations of chromosomes in wheat (Triticum aestivum L.)

open access: yesBMC Plant Biology, 2021
Background DNA sequence composition affects meiotic recombination. However, the correlation between tandem repeat composition and meiotic recombination in common wheat (Triticum aestivum L.) is unclear.
Yang Zou   +4 more
doaj   +1 more source

Probabilistic approaches to alignment with tandem repeats [PDF]

open access: yesAlgorithms for Molecular Biology, 2013
Peer-reviewed and presented as part of the 13th Workshop on Algorithms in Bioinformatics (WABI2013)
Michal Nánási   +2 more
openaire   +4 more sources

A Census of Tandemly Repeated Polymorphic Loci in Genic Regions Through the Comparative Integration of Human Genome Assemblies

open access: yesFrontiers in Genetics, 2018
Polymorphic Tandem Repeat (PTR) is a common form of polymorphism in the human genome. A PTR consists in a variation found in an individual (or in a population) of the number of repeating units of a Tandem Repeat (TR) locus of the genome with respect to ...
Loredana M. Genovese   +11 more
doaj   +1 more source

Counting short tandem repeats [PDF]

open access: yesNature Methods, 2020
A method using CRISPR–Cas technology, nanopore sequencing and bioinformatics enables quantification of short tandem repeats with high accuracy.
openaire   +2 more sources

Condensin Promotes Position Effects within Tandem DNA Repeats via the RITS Complex

open access: yesCell Reports, 2016
Summary: Tandem repetitive DNA is highly abundant in eukaryotic genomes and contributes to transcription control and genome stability. However, how the individual sequences within tandem repeats behave remains largely unknown.
Haijin He   +4 more
doaj   +1 more source

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