Results 91 to 100 of about 11,164 (212)

Enhancing Metabolic Engineering in Medicinal Plants Through Prime Editing

open access: yes
Plant Biotechnology Journal, EarlyView.
Haomiao Yu   +9 more
wiley   +1 more source

Adjunctive Therapies in Periodontitis: Current Concepts and the Future

open access: yesJournal of Periodontal Research, Volume 61, Issue 2, Page 138-164, February 2026.
This graphical abstract summarizes the translational pathway from preclinical research to clinical implementation of adjunctive therapies for periodontitis, highlighting key barriers, innovative therapeutic strategies, and emerging tools that aim to bridge experimental discoveries with patient care.
Rafael Scaf de Molon   +4 more
wiley   +1 more source

Tanshinone IIA pretreatment attenuates hepatic ischemia-reperfusion

open access: yesFrontiers in Bioscience, 2012
Tanshinone IIA (Tan IIA), an active component derived from Salvia miltiorrhiza root, has been used to treat various ischemic cardiovascular and cerebrovascular diseases. However, its impact on hepatic ischemia/reperfusion (I/R) injury remains unclear. Here, we addressed this issue by using a 90-minute partial liver ischemia model.
Yan-yan, Qi   +10 more
openaire   +2 more sources

Effects of the coexisting diterpenoid tanshinones on the pharmacokinetics of cryptotanshinone and tanshinone IIA in rat

open access: yesEuropean Journal of Pharmaceutical Sciences, 2007
Tanshinone II(A) and cryptotanshinone are the main pharmacologically active components in the Chinese herb drug Salvia miltiorrhiza Bge. The objective of this study was to investigate the effect of coexisting tanshinones in liposoluble ethanol extract of S. miltiorrhiza Bge.
Min, Song   +3 more
openaire   +2 more sources

In Vitro Effect of Ferruginol, Tanshinone, and Carnosol Analogues on the Proliferation of Three Breast Cancer Cell Lines

open access: yesMolecules
Ferruginol, tanshinones and carnosol are considered privileged natural products due to their demonstrated diverse biological activities with relevance to cancer research.
Miguel A. González-Cardenete   +3 more
doaj   +1 more source

Discovery of tanshinone derivatives with anti-MRSA activity via targeted bio-transformation

open access: yesSynthetic and Systems Biotechnology, 2016
Two potent anti-MRSA tanshinone glycosides (1 and 2) were discovered by targeted microbial biotransformation, along with rapid identification via MS/MS networking.
Wenni He   +15 more
doaj   +1 more source

Research Center for Ethnomedicines [PDF]

open access: yes, 2003
I. 伝統薬物に関するデータベース(ETHMEDmmm)の構築和漢薬・アーユルヴェーダ薬物データベースを新たに開発し,学術データの構築を開始した。Il. 伝統薬物の薬効の評価と解析に関する研究1 )難治性の神経疾患に対する有効性の検討とそれらの薬理作用の機序に関する研究インド生薬Ash wagandha から,ラット大脳皮質神経の初代培養細胞における神経突起伸展とシナプス形成作用を促進する成分を明らかにし,アルツハイマー病原因物質のアミロイドβ により障害を受けた神経細胞においても ...
Dawa   +4 more
core   +1 more source

Micro-RNA-1 is decreased by hypoxia and contributes to the development of pulmonary vascular remodeling via regulation of sphingosine kinase 1 [PDF]

open access: yes, 2018
Sphingosine kinase 1 (SphK1) upregulation is associated with pathologic pulmonary vascular remodeling in pulmonary arterial hypertension (PAH), but the mechanisms controlling its expression are undefined.
Chen, Jiwang   +6 more
core   +1 more source

Rosmarinic Acid Synthase 1 Phosphorylation by SmMAPK3 Is Required for Salicylic Acid‐Induced Salvianolic Acid Accumulation in Salvia miltiorrhiza Hairy Roots

open access: yesPlant Biotechnology Journal, Volume 24, Issue 2, Page 734-751, February 2026.
ABSTRACT Salvianolic acid is the main active component of Salvia miltiorrhiza and holds significant value in the clinical treatment of myocardial ischemia and hypoxia. Previous studies have shown that salicylic acid (SA) can significantly promote the accumulation of salvianolic acid, but its molecular mechanism remains incompletely understood.
Xuecui Yin   +6 more
wiley   +1 more source

Synergistic Accumulative Effect of Salicylic Acid and Dibutyl Phthalate on Paclitaxel Production in Corylus avellana Cell Culture [PDF]

open access: yes, 2013
Suspension cell cultures of Corylus avellana were challenged with salicylic acid and its combined use with dibutyl phthalate solvent. Salicylic acid with concentrations of 12.5, 25 and 50 mg L–1 and 10% (v/v) dibutyl phthalate were used and added on day ...
Behmanesh, M.   +4 more
core  

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