Results 81 to 90 of about 11,335 (232)

Biomimetic Cell Membrane‐Coated MOFs System for Targeted Cancer Therapy

Advanced Science, Volume 13, Issue 21, 13 April 2026.
Biomimetic MOF‐based drug delivery nanoplatforms synthesized using liposomes or cell membranes as camouflage for multiple cancer therapeutics. ABSTRACT The integration of metal‐organic frameworks (MOFs) with cell membrane coatings has emerged as a revolutionary strategy to enhance the therapeutic efficacy of cancer nanomedicine.
Qilu Wu, Jia Song Deon Chon, Yuxiao Feng, Kang Liang, Shiming Li, Can Yang Zhang, Jun Ge   +6 more
wiley   +1 more source

Synthesis and Characterization of Sulfonamide‐Schiff Bases, and Investigation of Cytotoxic, Antioxidant, HDAC, and Apoptotic Activities in Human Colon Cancer Cells (DLD‐1 and HT‐29)

Archiv der Pharmazie, Volume 359, Issue 4, April 2026.
New sulfonamide‐Schiff bases were synthesized, characterized, and investigated for their cytotoxic, antioxidant, HDAC, and apoptotic activities in human colon cancer cells (DLD‐1 and HT‐29). Compounds 3c and 3d emerged as promising candidates to act as selective therapeutic agents by targeting the p38/MAPK‐ERK1 pathway in colorectal cancer.
Seda Mesci, Berna Kocaman, Aliye Gediz Erturk, Emine Bagdatli, Burak Yazgan, Tuba Yildirim   +5 more
wiley   +1 more source

A review study on medicinal plants affecting amnesia through cholinergic system [PDF]

, 2012
Neurotransmitter modification is an important method for the treatment of memory loss or amnesia. Cholinomimetic drugs, particularly, acetylcholine esterase inhibitors are the mainstream in pharmacotherapy of amnesia. Donepezil, tacrine, galantamine, and
Baradaran, Azar., Rabiei, Zahra., Rafieian, Morteza., shirzad, Hedayatollah.   +3 more
core  

An overview of the anti-cancer actions of Tanshinones, derived from Salvia miltiorrhiza (Danshen)

Exploration of Targeted Anti-tumor Therapy, 2020
Tanshinone is a herbal medicinal compound described in Chinese medicine, extracted from the roots of Salvia miltiorrhiza (Danshen). This family of compounds, including Tanshinone IIA and Tanshinone I, have shown remarkable potential as anti-cancer ...
Irum Naz, Myriam Merarchi, Shanaya Ramchandani, Muhammad Rashid Khan, Muhammad Nouman Malik, Sumaira Sarwar, Acharan S Narula, Kwang Seok Ahn   +7 more
doaj   +1 more source

Combining Small‐Molecular Compounds With CAR T‐Cell Therapy: Novel Strategies for Enhanced Cancer Immunotherapy

Cancer Innovation, Volume 5, Issue 2, April 2026.
Chimeric antigen receptor (CAR) T‐cell therapy, although revolutionary for haematological malignancies, faces significant challenges, including T‐cell exhaustion, limited persistence, and treatment‐related toxicity. The integration of small‐molecule compounds offers a promising strategy to overcome these limitations.
Rangzi Yi, Zijian Zhang, Yang Yang, Haichuan Zhu   +3 more
wiley   +1 more source

Breathing Signature as Vitality Score Index Created by Exercises of Qigong: Implications of Artificial Intelligence Tools Used in Traditional Chinese Medicine. [PDF]

, 2019
Rising concerns about the short- and long-term detrimental consequences of administration of conventional pharmacopeia are fueling the search for alternative, complementary, personalized, and comprehensive approaches to human healthcare.
Dethlefs, Brent A, Lee, Katherine L, Li, Shengwen Calvin, Loudon, William G, Luo, Jane, Su, Qingning, Zhang, Junjie   +6 more
core   +1 more source

Tanshinone IIA Protects Against Cardiac Hypertrophy via Inhibiting Calcineurin/Nfatc3 Pathway

International Journal of Biological Sciences, 2011
Pathological cardiac hypertrophy induced by adrenergic overactivation can subsequently develop to heart failure which remains as a leading cause of mortality worldwide.
Xueying Tan, Jianping Li, Xinyue Wang, Nan Chen, Benzhi Cai, Gang Wang, Hongli Shan, Deli Dong, Yanju Liu, Xingda Li, Fan Yang, Xin Li, Peng Zhang, Xueqi Li, Baofeng Yang, Yanjie Lu
doaj  

Zhenyuan Solid Drink Ameliorates Inflammation and Oxidative Stress in Isoproterenol‐Induced Ischemic Myocardial Infarction via TLR4/NF‐κB Pathway and PI3K/AKT1/NRF2 Pathway in Rats

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
ZYSD exerts curative and preventive cardioprotection against isoproterenol‐induced myocardial infarction through synergistic interaction with probiotics, exerting antioxidant and anti‐inflammatory effects. ABSTRACT Zhenyuan Solid Drink (ZYSD) is a formulation consisting of 6 medicinal herbs that can be used as both food and medicinal materials in China.
Jiawen Huang, Tian Yu, Guoyi Li, Kechao Nie, Donghua Liu, Cong Meng, Xiaoling Shen, Linchun Fu, Liang Long, Zhuotao Fu, Zhitong Deng, Yingjie Hu   +11 more
wiley   +1 more source

Molecular mechanism of tanshinone IIA and cryptotanshinone in platelet anti-aggregating effects: an integrated study of pharmacology and computational analysis. [PDF]

, 2015
Tanshinone IIA and cryptotanshinone are two pharmacologically active diterpenoids extracted from the roots of Salvia milthiorriza Bunge, a plant used in Chinese traditional medicine for the treatment of some cardiovascular and cerebrovascular disease ...
Bifulco G., Cantone V., Chini M.G., De Feo V., MAIONE, FRANCESCO, MASCOLO, NICOLA DOMENICO C. FERDINANDO   +5 more
core  

Biological aspects of mTOR in leukemia [PDF]

, 2018
The mammalian target of rapamycin (mTOR) is a central processor of intra-and extracellular signals, regulating many fundamental cellular processes such as metabolism, growth, proliferation, and survival.
Bianchi, Mp, Gianfelici, V, Mirabilii, S, Piedimonte, M, Ricciardi, Mr, Tafuri, A.   +5 more
core   +1 more source