Results 71 to 80 of about 11,335 (232)

Climate change and crop resilience: harnessing metabolomics for predicting stress tolerance

New Phytologist, EarlyView.
Summarised methodology for metabolite biomarker discovery and genomic targets selection for those metabolites to predict high‐throughput phenotypic and agronomic traits of interest for direct uptake in breeding programmes. Summary Global warming is driving climate change to levels not experienced since the advent of agriculture, primarily due to ...
Agyeya Pratap, Arash Fazeli, Ali Bandehagh, Nicolas L. Taylor   +3 more
wiley   +1 more source

Countercurrent chromatography in analytical chemistry (IUPAC technical report) [PDF]

, 2009
© 2009 IUPACCountercurrent chromatography (CCC) is a generic term covering all forms of liquid-liquid chromatography that use a support-free liquid stationary phase held in place by a simple centrifugal or complex centrifugal force field. Biphasic liquid
Abbey, Abe, Abe, Abe, Akiba, Akiba, Akiba, Alain Berthod, Bauer, Bauer, Berthod, Berthod, Berthod, Berthod, Berthod, Berthod, Billardello, Boris Spivakov, Chen, Chen, Chen, Chen, Chmutova, Chmutova, Chmutova, Conway, Conway, Conway, Countercurrent Chromatography, Dekker, Fedotov, Fitz, Friesen, Fujita, Garcia Dominguez, Hashimoto, Hashimoto, Ian A. Sutherland, Ikai, Ito, Ito, Ito, Ito, Ito, Jin, Jin, Jin, Kawamura, Kawamura, Kidwell, Kitazume, Kitazume, Kitazume, Kitazume, Kitazume, Kong, Lee, Lee, Lee, Lee, Liu, Ma, Ma, Mandava, Mandava, Marston, Marston, Marston, Maryutina, Maryutina, Maryutina, Maryutina, Maryutina, Matsuda, Menet, Muralidharan, Nakamura, Nakamura, Oleg Shpigun, Pauli, Pukhovskaya, Ruiz, Ruiz, Ruth, Schaufelberger, Schaufelberger, Schreiber, Shang, Spivakov, Spivakov, Spivakov, Stark, Sutherland, Tanaka, Tatyana Maryutina, Thurman, Tian, Usuda, Usuda, Wang, Wang, Watkins, Winterhalter, Wood, Wu, Yanagida, Yang, Yang, Yang, Yoshida, Yu, Zhang, Zhang   +112 more
core   +2 more sources

Local Application of Tanshinone IIA protects mesenchymal stem cells from apoptosis and promotes fracture healing in ovariectomized mice

Journal of Orthopaedic Surgery and Research
Background Elderly patients suffering from osteoporotic fractures are more susceptible to delayed union or nonunion, and their bodies then are in a state of low-grade chronic inflammation with decreased antioxidant capacity. Tanshinone IIA is widely used
Shao Cheng, Xiaohui Hu, Kanghui Sun, Ziyu Huang, Yongjian Zhao, Yueli Sun, Bo Zeng, Jing Wang, Dongfeng Zhao, Sheng Lu, Qi Shi, Yongjun Wang, Weian Zhang, Xinhua Liu, Bing Shu   +14 more
doaj   +1 more source

Sodium Tanshinone IIA Sulfonate Attenuates Tumor Oxidative Stress and Promotes Apoptosis in an Intermittent Hypoxia Mouse Model

Technology in Cancer Research & Treatment, 2020
Objective: Intermittent hypoxia, a significant feature of obstructive sleep apnea, has pro-tumorigenic effects. Here, we investigated the effect of sodium tanshinone IIA sulfonate on oxidative stress and apoptosis in a mouse model of Lewis lung carcinoma
Xiao-Bin Zhang PhD, Xiao-Yang Chen PhD, Peng Sun MD, Xiao-Man Su Nurse, Hui-Qing Zeng PhD, Yi-Ming Zeng PhD, Miao Wang MD, Xiongbiao Luo PhD   +7 more
doaj   +1 more source

Targeting EZH2 in Cancer: From Molecular Mechanisms to Clinical Translation

MedComm – Oncology, Volume 5, Issue 2, June 2026.
The abnormal overexpression or gain‐of‐function mutations of EZH2 play a significant role in cancer occurrence and progression, highlighting the importance and potential of EZH2 as a cancer biomarker. Therefore, screening for effective and safe small‐molecule inhibitors, degraders, and natural compounds targeting EZH2 through preclinical cancer models ...
Xi Zhong, Jieni Li, Mingxuan Pan, Xiaoxue Ke, Hongjuan Cui   +4 more
wiley   +1 more source

Herb Target Prediction Based on Representation Learning of Symptom related Heterogeneous Network. [PDF]

, 2019
Traditional Chinese Medicine (TCM) has received increasing attention as a complementary approach or alternative to modern medicine. However, experimental methods for identifying novel targets of TCM herbs heavily relied on the current available herb ...
Chen, Jianxin, Gao, Zhuye, Hu, Xiaochen, Li, Peng, Liu, Baoyan, Peng, Yonghong, Wang, Ning, Xu, Hao, Yang, Kuo, Zhang, Runshun, Zhou, Xuezhong, Zhu, Qiang   +11 more
core   +1 more source

Cardiovascular Benefits of Salvia miltiorrhiza (Danshen) Supplementation: Bioactive Constituents, Mechanisms, Clinical Evidence and Implications for Nutritional Care

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
Salvia miltiorrhiza (Danshen) contains bioactive tanshinones, including tanshinone IIA, cryptotanshinone, and tanshinone I, that exert cardioprotective effects through coordinated modulation of vascular endothelial growth factor receptor (VEGFR), transforming growth factor beta 1 (TGF‐β1), transforming growth factor beta receptor (TGF‐βR), toll‐like ...
Akash Vikal, Rashmi Maurya, Preeti Patel, Balak Das Kurmi, William N. Setzer, Javad Sharifi‐Rad, Daniela Calina   +6 more
wiley   +1 more source

Aldose Reductase Inhibitory Activity of Chinese Crude Drug "Danshen" [PDF]

, 2000
漢薬“丹参”の基源植物である丹参（Salvia miltiorhiza）及び中国新彊において丹参（S.miltiorhiza）の代用品として用いられている新彊丹参（S.deserta）のアルドース還元酵素阻害活性成分を調べたところ，両者の活性成分は全く異なっていた。さらに，丹参（S.miltiorhiza）の代用品として用いられている10種を含む17種類のSalvia属植物について，水およびメタノールエキスのアルドース還元酵素阻害活性およびLC-MS分析を比較した結果も ...
手塚 康弘, 門田 重利
core   +1 more source

Arbuscular Mycorrhizal Fungi Regulate the Growth and Phyto-Active Compound of Salvia miltiorrhiza Seedlings

Applied Sciences, 2017
Roots and rhizomes of Salvia miltiorrhiza (S. miltiorrhiza) are widely used for the treatment of cardiovascular diseases. Arbuscular mycorrhizal fungi (AMFs) have been shown to enhance plant growth and increase secondary metabolites concentration in many
Ye Yang, Xiaohong Ou, Guang Yang, Yunsheng Xia, Meilan Chen, Lanping Guo, Dahui Liu   +6 more
doaj   +1 more source

Tanshinone IIA inhibits hypoxia-induced pulmonary artery smooth muscle cell proliferation via Akt/Skp2/p27-associated pathway. [PDF]

PLoS ONE, 2013
We previously showed that tanshinone IIA ameliorated the hypoxia-induced pulmonary hypertension (HPH) partially by attenuating pulmonary artery remodeling.
Ying Luo, Dun-Quan Xu, Hai-Ying Dong, Bo Zhang, Yi Liu, Wen Niu, Ming-Qing Dong, Zhi-Chao Li   +7 more
doaj   +1 more source