Results 51 to 60 of about 11,335 (232)

Tanshinones, Critical Pharmacological Components in Salvia miltiorrhiza [PDF]

Frontiers in Pharmacology, 2019
Salvia miltiorrhiza Bunge, a member of the Lamiaceae family, is valued in traditional Chinese Medicine. Its dried root (named Danshen) has been used for hundreds of years, primarily for the treatment of cardiovascular and cerebrovascular diseases. Tanshinones are the main active ingredients in S.
Zhouqian Jiang, Zhouqian Jiang, Wei Gao, Wei Gao, Luqi Huang   +4 more
openaire   +3 more sources

Tanshinone IIA attenuates the stemness of breast cancer cells via targeting the miR-125b/STARD13 axis

Experimental Hematology & Oncology, 2022
Background Tanshinone II A is an effective component extracted from Salvia miltiorrhiza and the roles of Tanshinone IIA in regulating the stemness of tumor cells remain unclear.
Xiaoman Li, Qi Jia, Yinyin Zhou, Xuan Jiang, Li Song, Yuanyuan Wu, Aiyun Wang, Wenxing Chen, Shijun Wang, Yin Lu   +9 more
doaj   +1 more source

Acute myocardial infarction therapy using calycosin and tanshinone co-loaded; mitochondrion-targeted tetrapeptide and cyclic arginyl-glycyl-aspartic acid peptide co-modified lipid-polymer hybrid nano-system: preparation, characterization, and anti myocardial infarction activity assessment

Drug Delivery, 2022
Acute myocardial infarction (AMI) is one of the most common ischemic heart diseases. However, lack of sufficient drug concentration (in the ischemic heart) is the major factor of treatment failure.
Jieke Yan, Jing Guo, Yuzhen Wang, Xiaowei Xing, Xuguang Zhang, Guanghao Zhang, Zhaoqiang Dong   +6 more
doaj   +1 more source

Endothelin-1-induced hypertrophic alterations and heme oxygenase-1 expression in cardiomyoblasts are counteracted by beta estradiol: in vitro and in vivo studies [PDF]

, 2018
L
Balla, György, Barta, Tünde, Haines, David Donald, Lekli, István, Tósaki, Ágnes, Tósaki, Árpád   +5 more
core   +1 more source

Etiology, pathogenesis, diagnosis and treatment of oral submucous fibrosis

口腔疾病防治, 2021
Oral submucous fibrosis (OSF) is a chronic disease that produces scars, tissue fibrosis, and precancerous lesions. Epidemiological studies have shown that chewing betel nut is the most significant risk factor for OSF.
JIAN Xinchun, GAO Xing
doaj   +1 more source

Chinese Medicines Induce Cell Death: The Molecular and Cellular Mechanisms for Cancer Therapy [PDF]

, 2014
published_or_final_versio
CHEUNG, F, Feng, Y, Kobayashi, S, Li, C, TAN, HY, Wang, N, Wang, X, Zhong, S   +7 more
core   +3 more sources

A Biomedical Investigation of the Hepatoprotective Effect of Radix salviae miltiorrhizae and Network Pharmacology-Based Prediction of the Active Compounds and Molecular Targets [PDF]

, 2017
published_or_final_versio
Cheung, F, Feng, Y, HONG, M, LI, S, Tan, HY, Wang, N   +5 more
core   +4 more sources

Nitric Oxide Plays a Central Role in Water Stress-Induced Tanshinone Production in Salvia miltiorrhiza Hairy Roots

Molecules, 2015
Nitric oxide (NO), a well-known signaling molecule plays an important role in abiotic and biotic stress-induced production of plant secondary metabolites.
Xuhong Du, Chenlu Zhang, Wanli Guo, Weibo Jin, Zongsuo Liang, Xijun Yan, Zhixin Guo, Yan Liu, Dongfeng Yang   +8 more
doaj   +1 more source

The Expression Profiles of the Salvia miltiorrhiza 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase 4 Gene and Its Influence on the Biosynthesis of Tanshinones

Molecules, 2022
Salvia miltiorrhiza is a medicinal plant that synthesises biologically-active tanshinones with numerous therapeutic properties. An important rate-limiting enzyme in the biosynthesis of their precursors is 3-hydroxy-3-methylglutaryl-coenzyme A reductase ...
Małgorzata Majewska, Piotr Szymczyk, Jan Gomulski, Agnieszka Jeleń, Renata Grąbkowska, Ewa Balcerczak, Łukasz Kuźma   +6 more
doaj   +1 more source

Mass Spectrometry Imaging‐Assisted Discovery of Gallotannin Biosynthetic Genes in the Root of Paeonia suffruticosa

Advanced Science, EarlyView.
An integrated approach combining mass spectrometry imaging, transcriptomics, and phylogenetic analysis facilitated the efficient identification of genes involved in gallotannin biosynthesis in Paeonia suffruticosa. As a result, a key UGT and several SCPL acyltransferases responsible for biosynthesizing pentagalloylglucose were successfully identified ...
Yushi Liu, Wenna Duan, Weiwei Tang, Yucheng Zhao, Bin Li   +4 more
wiley   +1 more source