Preclinical and clinical examinations of
, 2006 Salvia miltiorrhiza (Labiatae, Laminaceae), danshen, is an annual sage mainly found in China and neighboring countries. The crude drug (dried root) and its preparations are currently used in China to treat patients suffering from heart attack, angina ...
Lien Eric +3 more
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Genome-wide analysis, molecular cloning and expression profiling reveal tissue-specifically expressed, feedback-regulated, stress-responsive and alternatively spliced novel genes involved in gibberellin metabolism in Salvia miltiorrhiza [PDF]
, 2015 Conserved domains of enzymes involved in gibberellin metabolism in S. miltiorrhiza. Conserved domains of enzymes involved in gibberellin metabolism in S. miltiorrhiza are shown.
Caili Li +3 more
core +6 more sources
Molecules, 2022 The present study characterizes the 5′ regulatory region of the SmMEC gene. The isolated fragment is 1559 bp long and consists of a promoter, 5′UTR and 31 nucleotide 5′ fragments of the CDS region. In silico bioinformatic analysis found that the promoter
Piotr Szymczyk +4 more
doaj +1 more source
Tanshinones: Sources, Pharmacokinetics and Anti-Cancer Activities [PDF]
International Journal of Molecular Sciences, 2012 Tanshinones are a class of abietane diterpene compound isolated from Salvia miltiorrhiza (Danshen or Tanshen in Chinese), a well-known herb in Traditional Chinese Medicine (TCM). Since they were first identified in the 1930s, more than 40 lipophilic tanshinones and structurally related compounds have been isolated from Danshen.
Yong Zhang +5 more
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Molecular Mechanism of Tanshinone against Prostate Cancer
Molecules, 2022 Prostate cancer (PCa) is the most common malignant tumor of the male urinary system in Europe and America. According to the data in the World Cancer Report 2020, the incidence rate of PCa ranks second in the prevalence of male malignant tumors and varies worldwide between regions and population groups.
Wei Li +6 more
openaire +3 more sources
Neural Regeneration Research, 2017 Tanshinone IIA, extracted from Salvia miltiorrhiza Bunge, exerts neuroprotective effects through its anti-inflammatory, anti-oxidative and anti-apoptotic properties. This study intravenously injected tanshinone IIA 20 mg/kg into rat models of spinal cord
Yong-dong Yang +4 more
doaj +1 more source
Tissue-smashing based ultra-rapid extraction of chemical constituents in herbal medicines [PDF]
, 2014 postprin
Chen, C +5 more
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Hellenic Journal of Cardiology, 2018 Objective: To investigate the protective activity of tanshinone in a rat model of myocardial ischemia-reperfusion and determine its effect on the expression of Bcl-2 and Bax in cardiomyocytes.
Rui Guo, Gen Li
doaj +1 more source
Protection of lethal toxicity of endotoxin by Salvia miltiorrhiza BUNGE is via reduction in tumor necrosis factor alpha release and liver injury [PDF]
, 2006 Lipopolysaccharide (LPS) has been implicated as one of the major cause of Gram-negative bacteria-induced sepsis that are life-threatening syndromes occurring in intensive care unit patients. Many natural products derived from medicinal plants may contain
Chan, DKO +4 more
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What Does It Take to Synergistically Combine Sub-Potent Natural Products into Drug-Level Potent Combinations? [PDF]
, 2012 10.1371/journal.pone.0049969PLoS ...
A Sivachenko +63 more
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