Frontiers in Medicine, 2022 BackgroundFacial seborrheic dermatitis (FSD), also called facial seborrheic eczema, is a common disease affecting both male and female patients worldwide.
Qiang Fu +7 more
doaj +1 more source
Expression of P53 and Bcl2 Mammary Adenocarcinoma in C3H Mice Administered with Salvia Miltiorrhizae Bunge Root Extract [PDF]
, 2016 BackgroundBreast cancer is on the first or second most Malignancy in many places around the world. The incidence of breast cancer was increasing, also in Indonesia.
Dewi, L. S. (Liza) +2 more
core +3 more sources
Metabolism of Tanshinone IIA, Cryptotanshinone and Tanshinone I from Radix Salvia Miltiorrhiza in Zebrafish [PDF]
Molecules, 2012 The study aimed to investigate the potential of zebrafish in imitating mammal phase I metabolism of natural compounds. Three diterpenoid quinones from Radix Salvia miltiorrhiza, namely tanshinone IIA (TIIA), cryptotanshinone (Cry) and tanshinone I (TI) were selected as model compounds, and their metabolites mediated by zebrafish were characterized ...
Bing Wang +7 more
openaire +3 more sources
Interfering with HuR-RNA Interaction: Design, Synthesis and Biological Characterization of Tanshinone Mimics as Novel, Effective HuR Inhibitors [PDF]
, 2018 The human antigen R (HuR) is an RNA-binding protein known to modulate the expression of target mRNA coding for proteins involved in inflammation, tumorigenesis, and stress responses and is a valuable drug target.
Baj, Vanessa +18 more
core +2 more sources
Agronomy, 2023 The red root of Salvia miltiorrhiza Bunge, a famous traditional Chinese medicine (TCM), was caused by tanshinone in epidermis cells. In order to study the biological function of ncRNAs in the tanshinone synthesis, the expression patterns of mRNA and ...
Caicai Lin +4 more
doaj +1 more source
Combining Metabolomics and Transcriptomics to Characterize Tanshinone Biosynthesis in Salvia Miltiorrhiza [PDF]
, 2014 Plant natural products have been co-opted for millennia by humans for various uses such as flavor, fragrances, and medicines. These compounds often are only produced in relatively low amounts and are difficult to chemically synthesize, limiting access ...
Cui, Guanghong +12 more
core +3 more sources
A Zebrafish Compound Screen Reveals Modulation of Neutrophil Reverse Migration as an Anti-Inflammatory Mechanism [PDF]
, 2014 Diseases of failed inflammation resolution are common and largely incurable. Therapeutic induction of inflammation resolution is an attractive strategy to bring about healing without increasing susceptibility to infection.
Anderson, S.R. +20 more
core +1 more source
A Skin Lipidomics Study Reveals the Therapeutic Effects of Tanshinones in a Rat Model of Acne
Frontiers in Pharmacology, 2021 Tanshinone (TAN), a class of bioactive components in traditional Chinese medicinal plant Salvia miltiorrhiza, has antibacterial and anti-inflammatory effects, can enhance blood circulation, remove blood stasis, and promote wound healing.
Tingting Chen +13 more
doaj +1 more source
Effects of tanshinone on hyperandrogenism and the quality of life in women with polycystic ovary syndrome: protocol of a double-blind, placebo-controlled, randomised trial. [PDF]
, 2013 published_or_final_versio
Cong, J +6 more
core +1 more source
Frontiers in Plant Science, 2023 The roots of Salvia miltiorrhiza are the source of the traditional Chinese medicine danshen and the class of tanshinones, particular quinoid nor-diterpenoids of the abietane type.
Arpine Ayvazyan +7 more
doaj +1 more source