Results 101 to 110 of about 11,164 (212)

Astragalus membranaceus—Salvia miltiorrhiza Decoction Ameliorates Metabolic Syndrome and Gut Microbiota Dysbiosis Induced by High‐Fat Diet: A Comparative Study

Food Science &Nutrition, Volume 14, Issue 1, January 2026.
The optimal pairing ratio of ASDs against hyperlipidemia was systematically investigated. ASD maintains intestinal homeostasis and improves the systemic inflammatory response. A new LC–MS/MS method for the determination of derivatized SCFAs was established. ASD regulates the gut microbiota and its metabolites (SCFAs and BAs).
Haiyin Zhang, Haofang Wan, Yihang Lu, Yu He, Haitong Wan, Chang Li   +5 more
wiley   +1 more source

Emerging role of nuclear factor erythroid 2-related factor 2 in the mechanism of action and resistance to anticancer therapies [PDF]

, 2019
Nuclear factor E2-related factor 2 (NRF2), a transcription factor, is a master regulator of an array of genes related to oxidative and electrophilic stress that promote and maintain redox homeostasis. NRF2 function is well studied in in vitro, animal and
Deeni, Yusuf Y., Kankia, Ibrahim H., Langdon, Simon P., Paramasivan, Poornima   +3 more
core   +3 more sources

Paeoniflorin Ameliorates Spinal Cord Injury by Controlling Apoptosis and Ferroptosis in H2O2‐Damaged PC12 Cells

Immunity, Inflammation and Disease, Volume 14, Issue 1, January 2026.
ABSTRACT Background Spinal cord injury (SCI) leads to severe neurological dysfunction. Current therapeutic strategies remain limited, with poor recovery rates. Oxidative stress and ferroptosis are key mechanisms underlying secondary SCI. Paeoniflorin has anti‐inflammatory, antioxidant, and neuroprotective properties; however, its role in regulating ...
Zongyu Zhang, Zhijing Zhou, Peng Zhang, Yongfeng Huo   +3 more
wiley   +1 more source

SmEIL1 transcription factor inhibits tanshinone accumulation in response to ethylene signaling in Salvia miltiorrhiza

Frontiers in Plant Science
Among the bioactive compounds, lipid-soluble tanshinone is present in Salvia miltiorrhiza, a medicinal plant species. While it is known that ethephon has the ability to inhibit the tanshinones biosynthesis in the S.
Xiujuan Li, Man Xu, Ke Zhou, Siyu Hao, Liqin Li, Leran Wang, Wei Zhou, Guoyin Kai   +7 more
doaj   +1 more source

Tanshinone ⅡA Enhances Chemosensitivity of Breast Cancer Cells to Doxorubicin and Related Mechanism

Zhongliu Fangzhi Yanjiu, 2019
Objective To investigate the effects and mechanisms of tanshinone ⅡA on the chemosensitivity of human breast cancer MCF-7 and MDA-MB-231 cells to doxorubicin.
YUAN Yuan, ZHAO Qian, HU Zhansheng
doaj   +1 more source

Exosome‐Based Cartilage‐Targeted Delivery System: Strategies and Applications

Small Science, Volume 6, Issue 1, January 2026.
Construction strategies and applications of cartilage‐targeting exosomes. With the ageing of the global population, cartilage‐related diseases, such as osteoarthritis (OA) and intervertebral disc degeneration (IVDD), have increasingly become significant social problems threatening human health. Therefore, targeted therapy for cartilage is becoming more
Yao Wang, Bo Chen, Haodong Zhu, Zhenyu Sun   +3 more
wiley   +1 more source

Oridonin induces apoptosis and senescence in colorectal cancer cells by increasing histone hyperacetylation and regulation of p16, p21, p27 and c-myc [PDF]

, 2010
Background Oridonin, a tetracycline diterpenoid compound, has the potential antitumor activities. Here, we evaluate the antitumor activity and action mechanisms of oridonin in colorectal cancer.
Feng-Hou Gao, Xiao-Hui Hu, Wei Li, Hua Liu, Yan-Jie Zhang, Zhu-Ying Guo, Mang-Hua Xu, Shi-Ting Wang, Bin Jiang, Feng Liu, Ying-Zheng Zhao, Yong Fang, Fang-Yuan Chen, Ying-Li Wu   +13 more
core   +2 more sources

A review study on medicinal plants affecting amnesia through cholinergic system [PDF]

, 2012
Neurotransmitter modification is an important method for the treatment of memory loss or amnesia. Cholinomimetic drugs, particularly, acetylcholine esterase inhibitors are the mainstream in pharmacotherapy of amnesia. Donepezil, tacrine, galantamine, and
Baradaran, Azar., Rabiei, Zahra., Rafieian, Morteza., shirzad, Hedayatollah.   +3 more
core  

Countercurrent chromatography in analytical chemistry (IUPAC technical report) [PDF]

, 2009
© 2009 IUPACCountercurrent chromatography (CCC) is a generic term covering all forms of liquid-liquid chromatography that use a support-free liquid stationary phase held in place by a simple centrifugal or complex centrifugal force field. Biphasic liquid
Abbey, Abe, Abe, Abe, Akiba, Akiba, Akiba, Alain Berthod, Bauer, Bauer, Berthod, Berthod, Berthod, Berthod, Berthod, Berthod, Billardello, Boris Spivakov, Chen, Chen, Chen, Chen, Chmutova, Chmutova, Chmutova, Conway, Conway, Conway, Countercurrent Chromatography, Dekker, Fedotov, Fitz, Friesen, Fujita, Garcia Dominguez, Hashimoto, Hashimoto, Ian A. Sutherland, Ikai, Ito, Ito, Ito, Ito, Ito, Jin, Jin, Jin, Kawamura, Kawamura, Kidwell, Kitazume, Kitazume, Kitazume, Kitazume, Kitazume, Kong, Lee, Lee, Lee, Lee, Liu, Ma, Ma, Mandava, Mandava, Marston, Marston, Marston, Maryutina, Maryutina, Maryutina, Maryutina, Maryutina, Matsuda, Menet, Muralidharan, Nakamura, Nakamura, Oleg Shpigun, Pauli, Pukhovskaya, Ruiz, Ruiz, Ruth, Schaufelberger, Schaufelberger, Schreiber, Shang, Spivakov, Spivakov, Spivakov, Stark, Sutherland, Tanaka, Tatyana Maryutina, Thurman, Tian, Usuda, Usuda, Wang, Wang, Watkins, Winterhalter, Wood, Wu, Yanagida, Yang, Yang, Yang, Yoshida, Yu, Zhang, Zhang   +112 more
core   +2 more sources

Cardiac Potassium Channels: Physiological Insights for Targeted Therapy. [PDF]

, 2017
The development of novel drugs specifically directed at the ion channels underlying particular features of cardiac action potential (AP) initiation, recovery, and refractoriness would contribute to an optimized approach to antiarrhythmic therapy that ...
A. John Camm, Christopher L.-H. Huang, Feng J, Hansen RS, Kamalan Jeevaratnam, Karan R. Chadda, Lepran I, Milnes JT, Nichols CG, Rampe D, Rampe D, Shieh CC, Wang Z, Zhao X, Zhou J   +14 more
core   +1 more source