Results 61 to 70 of about 5,178 (152)

Tanshinone I Inhibits IL-1β-Induced Apoptosis, Inflammation And Extracellular Matrix Degradation In Chondrocytes CHON-001 Cells And Attenuates Murine Osteoarthritis

Drug Design, Development and Therapy, 2019
Xipeng Wang,1 Jianbo Fan,2 Xiaomin Ding,2 Yuyu Sun,2 Zhiming Cui,2 Wei Liu2 1Department of Orthopaedic Surgery, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430010, People’s Republic of
Wang X, Fan J, Ding X, Sun Y, Cui Z, Liu W   +5 more
doaj  

Anti-inflammatory Activity of Tanshinone-Related Diterpenes from Perovskia artemisioides Roots

Journal of Natural Products, 2023
Perovskia artemisioides is a perennial and aromatic plant widely distributed in the Baluchestan region of Iran. Phytochemical analysis of a n-hexane extract of P. artemisioides roots, guided by an analytical approach based on LC-ESI/LTQOrbitrap/MS/MS, yielded six previously undescribed diterpenoid compounds (2, 9-11, 16, and 20), and 19 known ...
Sadeghi, Zahra, Cerulli, Antonietta, Marzocco, Stefania, Moridi Farimani, Mahdi, Masullo, Milena, Piacente, Sonia   +5 more
openaire   +3 more sources

Atlas‐Based Mapping of Traditional Chinese Medicine Effects on Tumor Microcirculation Regulation

Immunity, Inflammation and Disease, Volume 14, Issue 2, February 2026.
ABSTRACT Background Tumor microcirculation plays a central role in the onset and progression of hypoxia, therapeutic resistance, and immune evasion within the tumor microenvironment. Traditional Chinese Medicine (TCM), characterized by its multi‐targeted and systemic regulatory properties, has garnered increasing attention for its potential to modulate
I Ho, Yijie Xie, Zhipeng Liu, Dingjun Cai   +3 more
wiley   +1 more source

Natural Products in Cancer Prevention and Therapy: Current Challenges and Future Directions

MedComm, Volume 7, Issue 2, February 2026.
Natural products play a pivotal role in cancer therapy. They induce cancer cell death by reprogramming four metabolic pathways while precisely targeting the tumor microenvironment and immune cells. These compounds not only leverage novel delivery systems for innovative applications but also demonstrate unique therapeutic efficacy across clinical stages:
Ruimiao Qian, Jun Ge, Ni Fan, Zheng Sun, Chengcheng Zhao, Yujiao Sun, Yingpeng Li, Yunfei Li, Hui Fu   +8 more
wiley   +1 more source

Traditional Chinese Medicine Modernization in Diagnosis and Treatment: Utilizing Artificial Intelligence and Nanotechnology

MedComm, Volume 7, Issue 2, February 2026.
Traditional Chinese medicine (TCM) faces great challenges during the development of modern medicine. Utilizing novel technologies such as artificial intelligence (AI) and nanotechnology facilitates TCM with great potential in precision diagnosis and improved treatments efficacy.
Wenqi Yu, Mengzhen Chen, Xueqi Tan, Xi Wei, Fan Sun, Hua Yan, Xue Xu, Hongcai Shang   +7 more
wiley   +1 more source

Solid Dispersions as a Tool for Innovation in the Food Industry: A Path From Pharma to Food

Journal of Food Science, Volume 91, Issue 2, February 2026.
ABSTRACT Solid dispersion (SD) is a technique used to improve the solubility of poorly water‐soluble compounds by dispersing them in a solid water‐friendly carrier. Current trends indicate that natural‐based alternatives are increasingly replacing synthetic carriers, benefiting the pharmaceutical industry, where they were first adopted, and paving the ...
Stephany C. de Rezende, Arantzazu Santamaria‐Echart, Madalena M. Dias, Maria Filomena Barreiro   +3 more
wiley   +1 more source

Three 11,12-seco-tanshinone derivatives from the rhizomes of Salvia miltiorrhiza

Journal of Asian Natural Products Research, 2020
Three new compounds named tanshinoic acid A (1), tanshinoic acid B (2), and tanshinoic acid C (3) were isolated from the rhizomes of Salvia miltiorrhiza, together with two known compounds methyl salvianolate A (4) and methyl salvianolate C (5). Their structures were determined on the basis of spectroscopic data (UV, IR, HRESIMS, 1 D and 2 D NMR).
Quan-Chang, Gu, Zhao-Kun, Yin, Zi-Ming, Feng, Jian-Shuang, Jiang, Xu, Zhang, Pei-Cheng, Zhang, Ya-Nan, Yang   +6 more
openaire   +2 more sources

Enhancing Metabolic Engineering in Medicinal Plants Through Prime Editing

Plant Biotechnology Journal, EarlyView.
Haomiao Yu, Xiao Feng, Xiaohang Zheng, Xiao Wang, Wenxin Zheng, Zhizhou Zhang, Yuanyuan Jiang, Ruiwu Yang, Li Zhang, Zhaohui Zhong   +9 more
wiley   +1 more source

Adjunctive Therapies in Periodontitis: Current Concepts and the Future

Journal of Periodontal Research, Volume 61, Issue 2, Page 138-164, February 2026.
This graphical abstract summarizes the translational pathway from preclinical research to clinical implementation of adjunctive therapies for periodontitis, highlighting key barriers, innovative therapeutic strategies, and emerging tools that aim to bridge experimental discoveries with patient care.
Rafael Scaf de Molon, Joao Paulo Steffens, Erica Dorigatti de Avila, Wim Teughels, Thomas E. Van Dyke   +4 more
wiley   +1 more source

Evaluation of the Antioxidant Potential of Salvia miltiorrhiza Ethanol Extract in a Rat Model of Ischemia-Reperfusion Injury

Molecules, 2011
The present study was undertaken to evaluate the protection potential of ethanol extract of Salvia miltiorrhiza (SMEE) against oxidative injury in the ischemia-reperfusion (I/R) model of rats in vivo.
Zengyong Qiao, Huajin Liu, Jiangwei Ma
doaj   +1 more source