Results 91 to 100 of about 8,021 (203)
Tanshinone IIA pretreatment attenuates ischemia/reperfusion-induced renal injury
Experimental and Therapeutic Medicine, 2016 Tanshinone IIA is a chemical compound extracted from the root of traditional Chinese herb Salvia miltiorrhiza Bunge. Tanshinone IIA has been suggested to possess anti-inflammatory activity and antioxidizing capability. Recently, accumulating results have indicated the antitumor activity of tanshinone IIA; thus, it has attracted increasing attention. In
Yan-Mei, Xu +3 more
openaire +3 more sources
Apoptosis Induced by Tanshinone IIA and Cryptotanshinone Is Mediated by Distinct JAK/STAT3/5 and SHP1/2 Signaling in Chronic Myeloid Leukemia K562 Cells [PDF]
, 2013 Though tanshinone IIA and cryptotanshinone possess a variety of biological effects such as anti-inflammatory, antioxidative, antimetabolic, and anticancer effects, the precise molecular targets or pathways responsible for anticancer activities of ...
Eun Jung Sohn +6 more
core +2 more sources
Pharmaceutical Biology, 2018 Context: Tanshinone IIA, commercially produced from Salvia miltiorrhiza Bunge (C.Y.Wu) (Labiatae), has various biological benefits. Currently, this compound is mainly extracted from plants.
Pengyu Zhang +5 more
doaj +1 more source
Exosome‐Based Cartilage‐Targeted Delivery System: Strategies and Applications
Small Science, Volume 6, Issue 1, January 2026.Construction strategies and applications of cartilage‐targeting exosomes. With the ageing of the global population, cartilage‐related diseases, such as osteoarthritis (OA) and intervertebral disc degeneration (IVDD), have increasingly become significant social problems threatening human health. Therefore, targeted therapy for cartilage is becoming more
Yao Wang +3 more
wiley +1 more source
Research Center for Ethnomedicines [PDF]
, 2003 I. 伝統薬物に関するデータベース（ETHMEDmmm）の構築和漢薬・アーユルヴェーダ薬物データベースを新たに開発し，学術データの構築を開始した。Il. 伝統薬物の薬効の評価と解析に関する研究1 ）難治性の神経疾患に対する有効性の検討とそれらの薬理作用の機序に関する研究インド生薬Ash wagandha から，ラット大脳皮質神経の初代培養細胞における神経突起伸展とシナプス形成作用を促進する成分を明らかにし，アルツハイマー病原因物質のアミロイドβ により障害を受けた神経細胞においても ...
Dawa +4 more
core +1 more source
Enhancing Metabolic Engineering in Medicinal Plants Through Prime Editing
Plant Biotechnology Journal, EarlyView.
Haomiao Yu +9 more
wiley +1 more source
Canadian Respiratory Journal, Volume 2026, Issue 1, 2026.Background Pulmonary fibrosis is a chronic disease characterized by progressive interstitial lung changes affecting alveolar epithelial cells and pulmonary vessels. Following COVID‐19, it has emerged as a significant sequela in severe cases, often with a poor prognosis.
Jia-Wei Zeng +3 more
wiley +1 more source
Cardiac Potassium Channels: Physiological Insights for Targeted Therapy. [PDF]
, 2017 The development of novel drugs specifically directed at the ion channels underlying particular features of cardiac action potential (AP) initiation, recovery, and refractoriness would contribute to an optimized approach to antiarrhythmic therapy that ...
A. John Camm +14 more
core +1 more source
NGHIÊN CỨU PHƯƠNG PHÁP PHÂN LẬP TANSHINONE IIA TỪ ĐAN SÂM LÀM CHẤT ĐỐI CHIẾU
Tạp chí Khoa học Đại học Đà Lạt, 2015 Tanshinone IIA đã được phân lập từ đan sâm (Salvia mitiorrhiza) làm chất đối chiếu. Phương pháp phân lập gồm các bước: chiết các thành phần thân dầu từ rễ đan sâm bằng n-hexan, phân lập tanshinone IIA bằng sắc ký cột silicagel và tinh chế bằng phương ...
Trịnh Thị Điệp, Trần Thanh Hà
doaj +1 more source
Determination and Pharmacokinetic of Peiminine in Beagle Dogs by UPLC‐MS/MS
International Journal of Analytical Chemistry, Volume 2026, Issue 1, 2026.This study centered on creating and validating a UPLC–MS/MS assay that is both reliable and simple, making it suitable for measuring peiminine levels in the plasma of beagle dogs. The established method was then employed with the ultimate goal of elucidating the pharmacokinetic behavior of the compound.
Qian Cheng +4 more
wiley +1 more source