Results 11 to 20 of about 8,021 (203)
Asian Journal of Pharmaceutical Sciences, 2017 Total tanshinones are lipophilic active constituents extracted from Salvia miltiorrhiza Bge. Tanshinone IIA and cryptotanshinone are the major components in total tanshinones.
Xifeng Zhai +4 more
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Tanshinone IIA: A Review of its Anticancer Effects [PDF]
Frontiers in Pharmacology, 2021 Tanshinone IIA (Tan IIA) is a pharmacologically lipophilic active constituent isolated from the roots and rhizomes of the Chinese medicinal herb Salvia miltiorrhiza Bunge (Danshen). Tan IIA is currently used in China and other neighboring countries to treat patients with cardiovascular system, diabetes, apoplexy, arthritis, sepsis, and other diseases ...
Zhong‐ying Fang +7 more
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Tanshinone IIA: A Promising Natural Cardioprotective Agent [PDF]
Evidence-Based Complementary and Alternative Medicine, 2012 Tanshinone IIA (Tan IIA) is a member of the major lipophilic components extracted from the root ofSalvia miltiorrhizaBunge, which is currently used in China and other neighboring countries to treat patients suffering from myocardial infarction (MI), angina pectoris, stroke, diabetes, sepsis, and other conditions.
Shang, Qinghua, Xu, Hao, Huang, Li
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Tanshinone IIA Stimulates Erythrocyte Phosphatidylserine Exposure [PDF]
Cellular Physiology and Biochemistry, 2012 Tanshinone IIA, an antimicrobial, antioxidant, antianaphylactic, antifibrotic, vasodilating, antiatherosclerotic, organo-protective and antineoplastic component from the rhizome of Salvia miltiorrhiza, is known to trigger apoptosis of tumor cells. Tanshinone IIA is effective in part through mitochondrial depolarization and altered gene expression ...
ZELENAK C. +9 more
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Tanshinone IIA Modulates Low Density Lipoprotein Uptake via Down-Regulation of PCSK9 Gene Expression in HepG2 Cells. [PDF]
PLoS ONE, 2016 Tanshinone IIA, one of the most pharmacologically bioactive phytochemicals isolated from Salvia miltiorrhiza Bunge, possesses several biological activities such as anti-inflammation, anti-cancer, neuroprotection and hypolipidemic activities.
Hung-Chen Chen +4 more
doaj +1 more source
Green Processing and Synthesis, 2023 Tanshinone IIA has a potential therapeutic effect on cerebral ischemia/reperfusion injury (CIRI). In this study, tanshinone IIA was encapsulated in poly(lactic-co-glycolic acid)-block-poly (ethylene glycol)-carboxylic acid (PLGA-PEG-COOH) nanoparticles ...
Zhang Xin +7 more
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Pharmaceutical Biology, 2023 Context Tanshinone IIA is an extract of Salvia miltiorrhiza Bunge (Labiatae) used to treat cardiovascular disorders. It shows potential anticonvulsant and cognition-protective properties.Objective We investigated the mechanism of tanshinone IIA on ...
Chen Jia +9 more
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Biomedicines, 2021 Abnormal and excessive accumulation of lipid droplets within hepatic cells is the main feature of steatosis and nonalcoholic fatty liver disease (NAFLD) or metabolic-associated fatty liver disease (MAFLD).
Wan-Yun Gao +5 more
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Molecular Medicine, 2023 Background Many studies have confirmed the association of aquaporins (AQPs) with abnormal amniotic fluid volume (AFV). In our previous experiments, we found that Tanshinone IIA was able to regulate the expression of AQP1 and AQP3.
Shuangjia Pan +5 more
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Tanshinone IIA pretreatment attenuates hepatic ischemia-reperfusion
Frontiers in Bioscience, 2012 Tanshinone IIA (Tan IIA), an active component derived from Salvia miltiorrhiza root, has been used to treat various ischemic cardiovascular and cerebrovascular diseases. However, its impact on hepatic ischemia/reperfusion (I/R) injury remains unclear. Here, we addressed this issue by using a 90-minute partial liver ischemia model.
Yan-yan, Qi +10 more
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