Results 21 to 30 of about 116,988 (242)
Journal of Pharmacological Sciences, 2009 .: Tanshinone IIA, one of the main active components from the Chinese herb Danshen, is widely used to treat cardiovascular diseases in Asian countries, especially in China.
Qiansheng Liang +5 more
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Mediators of Inflammation, 2022 Background. Radiotherapy is one of the major strategies for treating tumors, and it inevitably causes damage to relevant tissues and organs during treatment.
Gang Wang +10 more
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Tanshinone IIA inhibits AGEs-induced proliferation and migration of cultured vascular smooth muscle cells by suppressing ERK1/2 MAPK signaling [PDF]
Iranian Journal of Basic Medical Sciences, 2018 Objective(s): Vascular smooth muscle cells (VSMCs) play a key role in the pathogenesis of diabetic vascular disease. Our current study sought to explore the effects of tanshinone IIA on the proliferation and migration of VSMCs induced by advanced ...
Ming Lu +4 more
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Tanshinone IIA attenuates nerve structural and functional damage induced by nerve crush injury in rats. [PDF]
PLoS ONE, 2018 After peripheral nerve crush injury, the fibers of distal nerve segments gradually disintegrate, and axons regrow from the proximal nerve segment, eventually reaching the target organ.
Zhiyong Wang +4 more
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Pharmaceutical Biology, 2018 Context: Tanshinone IIA, commercially produced from Salvia miltiorrhiza Bunge (C.Y.Wu) (Labiatae), has various biological benefits. Currently, this compound is mainly extracted from plants.
Pengyu Zhang +5 more
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Tanshinone IIA inactivates Akt and induces caspase-dependent death in cervical cancer cells via the mitochondrial pathway [PDF]
Bangladesh Journal of Pharmacology, 2015 In human cervical cancer cells pro-apoptotic effect of tanshinone IIA isolated from the ethanol extract of Scutellaria barbata was investigated. Tanshinone IIA treatment resulted in apoptosis and mitochondrial membrane potential loss in the cervical ...
Hu Li, Yan Xu, Li Yang, Lei He
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The complex regulation of tanshinone IIA in rats with hypertension-induced left ventricular hypertrophy. [PDF]
PLoS ONE, 2014 Tanshinone IIA has definite protective effects on various cardiovascular diseases. However, in hypertension-induced left ventricular hypertrophy (H-LVH), the signaling pathways of tanshinone IIA in inhibition of remodeling and cardiac dysfunction remain ...
Hui Pang, Bing Han, Tao Yu, Zhen Peng
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Cellular Physiology and Biochemistry, 2014 Background: Tanshinone IIA inhibits the proliferation of pulmonary artery smooth muscle cells (PASMCs), but the potential mechanisms of its effects on PASMCs apoptosis remain unclear.
Minggang Chen +5 more
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Tanshinone IIA Inhibits High Glucose-Induced Collagen Synthesis via Nuclear Factor Erythroid 2-Related Factor 2 in Cardiac Fibroblasts [PDF]
Cellular Physiology and Biochemistry, 2018 Background/Aims: Diabetes is associated with increased incidence of myocardial dysfunction, which is partly characterized by interstitial and perivascular fibrosis.
Yi-Ting Tsai +6 more
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NGHIÊN CỨU PHƯƠNG PHÁP PHÂN LẬP TANSHINONE IIA TỪ ĐAN SÂM LÀM CHẤT ĐỐI CHIẾU
Tạp chí Khoa học Đại học Đà Lạt, 2015 Tanshinone IIA đã được phân lập từ đan sâm (Salvia mitiorrhiza) làm chất đối chiếu. Phương pháp phân lập gồm các bước: chiết các thành phần thân dầu từ rễ đan sâm bằng n-hexan, phân lập tanshinone IIA bằng sắc ký cột silicagel và tinh chế bằng phương ...
Trịnh Thị Điệp, Trần Thanh Hà
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