Results 11 to 20 of about 116,988 (242)

Preparation and characterisation of solid dispersions of tanshinone IIA, cryptotanshinone and total tanshinones [PDF]

Asian Journal of Pharmaceutical Sciences, 2017
Total tanshinones are lipophilic active constituents extracted from Salvia miltiorrhiza Bge. Tanshinone IIA and cryptotanshinone are the major components in total tanshinones.
Xifeng Zhai, Chunguang Li, George Binh Lenon, Charlie C.L. Xue, Weize Li   +4 more
doaj   +5 more sources

Tanshinone IIA stimulates erythrocyte phosphatidylserine exposure [PDF]

Cellular Physiology and Biochemistry, 2012
Contains fulltext : 109681.pdf (Publisher’s version ) (Open Access)Tanshinone IIA, an antimicrobial, antioxidant, antianaphylactic, antifibrotic, vasodilating, antiatherosclerotic, organo-protective and antineoplastic component from the
Lang, F., Zelenak, C., Rosaclerio, L., Pasham, V., Qadri, S.M., Lupescu, A., Tripodi, P.M., Faggio, C., Jilani, K., Pathare, G.T.   +9 more
core   +7 more sources

Neuron Regeneration and Proliferation Effects of Danshen and Tanshinone IIA [PDF]

Evidence-Based Complementary and Alternative Medicine, 2011
This study evaluates the proliferative effects of danshen and its monomer extract, tanshinone IIA, on Schwann cell proliferation. A piece of silicone rubber was guided across a 15-mm gap in the sciatic nerve of a rat.
Kuo, C.H., Chen, Y.S., Lin, J.Y., Fuu-Jen Tsai, Tien, Y.C., Wang, H.L., Ming-Chih Chou, Chien-Chung Lin, Yueh-Sheng Chen, Peng, W.H., Tsai, F.J., Jing-Ying Lin, Chih-Yang Huang, Tzang, B.S., Jui-Lung Shen, Yun-Chen Tien, Chou, M.C., Shen, J.L., Bor-Show Tzang, Wen-Huang Peng, Hwai-Lee Wang, Lin, C.C., Chia-Hua Kuo, Huang, C.Y.   +23 more
core   +4 more sources

Tanshinone IIA improves functional recovery in spinal cord injury-induced lower urinary tract dysfunction

Neural Regeneration Research, 2017
Tanshinone IIA, extracted from Salvia miltiorrhiza Bunge, exerts neuroprotective effects through its anti-inflammatory, anti-oxidative and anti-apoptotic properties. This study intravenously injected tanshinone IIA 20 mg/kg into rat models of spinal cord
Yong-dong Yang, Xing Yu, Xiu-mei Wang, Xiao-hong Mu, Feng He   +4 more
doaj   +2 more sources

Tanshinone IIA Attenuates Contrast-Induced Nephropathy via Nrf2 Activation in Rats

Cellular Physiology and Biochemistry, 2018
Background/Aims: Tanshinone IIA is a chemical compound extracted from Salvia miltiorrhiza Bunge, a perennial plant also known as red sage used in traditional Chinese medicine. Tanshinone IIA has been shown to protect against various organ injuries.
Rulian Liang, Qing Zhao, Guihua Jian, Dongsheng Cheng, Niansong Wang, Guangyuan Zhang, Feng Wang   +6 more
doaj   +3 more sources

Tanshinone IIA Downregulates Lipogenic Gene Expression and Attenuates Lipid Accumulation through the Modulation of LXRα/SREBP1 Pathway in HepG2 Cells

Biomedicines, 2021
Abnormal and excessive accumulation of lipid droplets within hepatic cells is the main feature of steatosis and nonalcoholic fatty liver disease (NAFLD) or metabolic-associated fatty liver disease (MAFLD).
Wan-Yun Gao, Pei-Yi Chen, Hao-Jen Hsu, Ching-Yen Lin, Ming-Jiuan Wu, Jui-Hung Yen   +5 more
doaj   +2 more sources

Effect of Supplementation of Tanshinone IIA and Sodium Tanshinone IIA Sulfonate on the Anticancer Effect of Epirubicin: AnIn VitroStudy [PDF]

Evidence-Based Complementary and Alternative Medicine, 2011
Tanshinone IIA (Tan IIA) and sodium tanshinone IIA sulfonate (STS) were found to have protective effects on cardiomyocyte against adriamycin-induced damage and may be used clinically.
Hung-Wen Lai, Szu-Erh Chan, Dar-Ren Chen, Chin-Cheng Su, Hui-Yi Lin, Shou-Jen Kuo, Su-Yu Chien   +6 more
core   +4 more sources

Tanshinone IIA: a Chinese herbal ingredient for the treatment of atherosclerosis

Frontiers in Pharmacology, 2023
Tanshinone IIA (Tan IIA) is a fat-soluble compound extracted from Salvia miltiorrhiza, which has a protective effect against atherosclerosis (AS). Tan IIA can inhibit oxidative stress and inflammatory damage of vascular endothelial cells (VECs) and ...
Chunkun Yang, Yan-Guang Mu, Shuanghong Li, Yang Zhang, Xiaoyuan Liu, Jun Li   +5 more
semanticscholar   +4 more sources

Tanshinone IIA inhibits hypoxia-induced pulmonary artery smooth muscle cell proliferation via Akt/Skp2/p27-associated pathway. [PDF]

PLoS ONE, 2013
We previously showed that tanshinone IIA ameliorated the hypoxia-induced pulmonary hypertension (HPH) partially by attenuating pulmonary artery remodeling.
Ying Luo, Dun-Quan Xu, Hai-Ying Dong, Bo Zhang, Yi Liu, Wen Niu, Ming-Qing Dong, Zhi-Chao Li   +7 more
doaj   +2 more sources

Tanshinone IIA and hepatocellular carcinoma: A potential therapeutic drug

Frontiers in Oncology, 2023
Because of its high prevalence and poor long-term clinical treatment effect, liver disease is regarded as a major public health problem around the world.
Hu Li, Peng Hu, Yajun Zou, Li-Juan Yuan, Yu-Cheng Xu, Xiaohui Zhang, Xiao Luo, Zhiqiang Zhang   +7 more
semanticscholar   +4 more sources