Results 11 to 20 of about 79,005 (262)

Preparation and characterisation of solid dispersions of tanshinone IIA, cryptotanshinone and total tanshinones

open access: yesAsian Journal of Pharmaceutical Sciences, 2017
Total tanshinones are lipophilic active constituents extracted from Salvia miltiorrhiza Bge. Tanshinone IIA and cryptotanshinone are the major components in total tanshinones.
Xifeng Zhai   +4 more
doaj   +6 more sources

Renoprotective Effects of Tanshinone IIA: A Literature Review

open access: yesMolecules, 2023
The kidney is an important organ in the human body, with functions such as urine production, the excretion of metabolic waste, the regulation of water, electrolyte and acid–base balance and endocrine release.
Zhengtao Chen   +7 more
semanticscholar   +4 more sources

Tanshinone IIA and hepatocellular carcinoma: A potential therapeutic drug

open access: yesFrontiers in Oncology, 2023
Because of its high prevalence and poor long-term clinical treatment effect, liver disease is regarded as a major public health problem around the world.
Hu Li   +7 more
semanticscholar   +4 more sources

Salvia miltiorrhiza and Tanshinone IIA reduce endothelial inflammation and atherosclerotic plaque formation through inhibiting COX-2.

open access: yesBiomedicine and Pharmacotherapy, 2023
The mechanisms of Salvia miltiorrhiza (SM) and Tanshinone IIA (Tan IIA) in the treatment of atherosclerosis was examined by combining network pharmacology and molecular biology experiments.
Xiangke Ma   +4 more
semanticscholar   +3 more sources

Tanshinone IIA: A Review of its Anticancer Effects [PDF]

open access: yesFrontiers in Pharmacology, 2021
Tanshinone IIA (Tan IIA) is a pharmacologically lipophilic active constituent isolated from the roots and rhizomes of the Chinese medicinal herb Salvia miltiorrhiza Bunge (Danshen).
Z. Fang   +5 more
semanticscholar   +4 more sources

Tanshinone IIA inhibits metastasis after palliative resection of hepatocellular carcinoma and prolongs survival in part via vascular normalization

open access: yesJournal of Hematology & Oncology, 2012
Background Promotion of endothelial normalization restores tumor oxygenation and obstructs tumor cells invasion, intravasation, and metastasis. We therefore investigated whether a vasoactive drug, tanshinone IIA, could inhibit metastasis by inducing ...
Wang Wen-Quan   +11 more
doaj   +3 more sources

Tanshinone IIA Restrains Hepatocellular Carcinoma Progression by Regulating METTL3-Mediated m6A Modification of TRIB3 mRNA [PDF]

open access: yesThe Turkish Journal of Gastroenterology
Background/Aims: Hepatocellular carcinoma (HCC) is a molecularly heterogeneous solid malignancy that carries a dismal prognosis. Tanshinone IIA (Tan-IIA) is involved in the regulation of N6-methyladenosine (m6A) modification and plays an anti-tumor role
Ying Jiang   +6 more
doaj   +2 more sources

Efficacy and safety of tanshinone IIA in combination with mesalazine in the treatment of ulcerative colitis: a Systematic review and meta-analysis [PDF]

open access: yesBMC Gastroenterology
Background Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by relapsing inflammation of the colon. Tanshinone IIA, a compound derived from traditional Chinese medicine, has demonstrated anti-inflammatory properties and may ...
Xiao Chen   +5 more
doaj   +2 more sources

Tanshinone IIA: A Promising Natural Cardioprotective Agent [PDF]

open access: yesEvidence-Based Complementary and Alternative Medicine, 2012
Tanshinone IIA (Tan IIA) is a member of the major lipophilic components extracted from the root ofSalvia miltiorrhizaBunge, which is currently used in China and other neighboring countries to treat patients suffering from myocardial infarction (MI), angina pectoris, stroke, diabetes, sepsis, and other conditions.
Shang, Qinghua, Xu, Hao, Huang, Li
openaire   +3 more sources

Tanshinone IIA attenuates AOM/DSS-induced colorectal tumorigenesis in mice via inhibition of intestinal inflammation

open access: yesPharmaceutical Biology, 2021
Context Tanshinone IIA is a natural extract derived from a Chinese medicinal herb with multiple bioactivities; however, whether and how tanshinone IIA protects against colorectal cancer (CRC) are uncertain.
Lijie Liu   +5 more
doaj   +1 more source

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