Experimental Hematology & Oncology, 2022 Background Tanshinone II A is an effective component extracted from Salvia miltiorrhiza and the roles of Tanshinone IIA in regulating the stemness of tumor cells remain unclear.
Xiaoman Li +9 more
doaj +1 more source
Endophyte Chaetomium globosum D38 Promotes Bioactive Constituents Accumulation and Root Production in Salvia miltiorrhiza [PDF]
, 2018 Salvia miltiorrhiza is known for tanshinones and salvianolic acids, which have been shown to have a protective effect against ROS, especially for cardiovascular diseases and other various ailments of human organs.
Han, T +9 more
core +3 more sources
Applied Sciences, 2020 Colorectal cancer is one of the most frequently diagnosed cancers worldwide. The aim of the present study was to simultaneously analyze compounds of Salviae miltiorrhizae Radix (SMR) and determine their cytotoxic effects on HCT-116 human colorectal ...
Bohyung Kang +4 more
doaj +1 more source
Tanshinone IIA inhibits hypoxia-induced pulmonary artery smooth muscle cell proliferation via Akt/Skp2/p27-associated pathway. [PDF]
PLoS ONE, 2013 We previously showed that tanshinone IIA ameliorated the hypoxia-induced pulmonary hypertension (HPH) partially by attenuating pulmonary artery remodeling.
Ying Luo +7 more
doaj +1 more source
Cryptotanshinone but not tanshinone IIA inhibits angiogenesis in vitro [PDF]
Experimental & Molecular Medicine, 2005 In the course of screening of angiogenesis inhibitor from natural products, cryptotanshinone from Salvia miltiorrhiza was isolated as a potent small molecule inhibitor of angiogenesis. Cryptotanshinone inhibits bFGF-induced angiogenesis of BAECs at ten micromolar ranges in vitro without cytotoxicity.
Jong Moon, Hur +3 more
openaire +2 more sources
A Zebrafish Compound Screen Reveals Modulation of Neutrophil Reverse Migration as an Anti-Inflammatory Mechanism [PDF]
, 2014 Diseases of failed inflammation resolution are common and largely incurable. Therapeutic induction of inflammation resolution is an attractive strategy to bring about healing without increasing susceptibility to infection.
Anderson, S.R. +20 more
core +1 more source
Tanshinone IIA and hepatocellular carcinoma: A potential therapeutic drug
Frontiers in Oncology, 2023 Because of its high prevalence and poor long-term clinical treatment effect, liver disease is regarded as a major public health problem around the world. Among them, viral hepatitis, fatty liver, cirrhosis, non-alcoholic fatty liver disease (NAFLD), and autoimmune liver disease are common causes and inducements of liver injury, and play an important ...
Hu Li +9 more
openaire +3 more sources
A Biomedical Investigation of the Hepatoprotective Effect of Radix salviae miltiorrhizae and Network Pharmacology-Based Prediction of the Active Compounds and Molecular Targets [PDF]
, 2017 published_or_final_versio
Cheung, F +5 more
core +4 more sources
Expression of P53 and Bcl2 Mammary Adenocarcinoma in C3H Mice Administered with Salvia Miltiorrhizae Bunge Root Extract [PDF]
, 2016 BackgroundBreast cancer is on the first or second most Malignancy in many places around the world. The incidence of breast cancer was increasing, also in Indonesia.
Dewi, L. S. (Liza) +2 more
core +3 more sources
Chinese Medicines Induce Cell Death: The Molecular and Cellular Mechanisms for Cancer Therapy [PDF]
, 2014 published_or_final_versio
CHEUNG, F +7 more
core +6 more sources