Results 51 to 60 of about 79,005 (262)

Tissue-smashing based ultra-rapid extraction of chemical constituents in herbal medicines [PDF]

, 2014
postprin
Chen, C, Fan, Y, Li, P, Qi, LW, So, KF, Yan, CP   +5 more
core   +1 more source

Prospective therapeutic potential of Tanshinone IIA: An updated overview

Pharmacological Research, 2021
In the past decades, the branch of complementary and alternative medicine based therapeutics has gained considerable attention worldwide. Pharmacological efficacy of various traditional medicinal plants, their products and/or product derivatives have been explored on an increasing scale. Tanshinone IIA (Tan IIA) is a pharmacologically active lipophilic
Mohammad Azam, Ansari, Farheen Badrealam, Khan, Haaris Ahsan, Safdari, Ahmad, Almatroudi, Mohammad A, Alzohairy, Mohammadreza, Safdari, Mehran, Amirizadeh, Suriya, Rehman, Mohammad Javed, Equbal, Mehboob, Hoque   +9 more
openaire   +2 more sources

What Does It Take to Synergistically Combine Sub-Potent Natural Products into Drug-Level Potent Combinations? [PDF]

, 2012
10.1371/journal.pone.0049969PLoS ...
A Sivachenko, AL Harvey, B Fantin, B Papp, BA Larder, Chu Qin, Chun Yan Tan, CM Overall, Cun Long Zhang, Daniel S. Sem, DJ Newman, DM Eisenberg, DX Kong, EF Carvalho-Netto, EM Williamson, EW Sayers, F Zhu, F Zhu, FR Stermitz, GA Cordell, GG Zhang, GR Zimmermann, GT Lewith, GV Georgakis, H Quach, H Wagner, H Xiong, H Yang, HA Junio, HS Kim, J Gertsch, J Jia, J Kaiser, JE Dancey, JH MacIndoe, JI Johnson, JW Li, K Hayashi, Kai Leng Tan, KS Smalley, L Dinan, L Xie, LJ Li, LL Silver, M Shabbir, M Thanou, NV Sergina, P Csermely, PH Chiu, R Barker Bausell, R Muller, R Staud, RH Shoemaker, T Efferth, TC Chou, TF Molinski, TI Oprea, W Kassouf, X Tong, XH Ma, XM Zhou, Y Pilpel, Yu Yang Jiang, Yu Zong Chen   +63 more
core   +3 more sources

Preparation of tanshinone IIA self-soluble microneedles and its inhibition on proliferation of human skin fibroblasts

Chinese Herbal Medicines, 2023
Objective Hypertrophic scars (HS) are a variety of skin tissue fibrosis disease that occurs in human skin, the effective therapeutic method of which is still inaccessible up to now.
Yanshan Zhan, Xiao-qi Xu, Xi Luo, Rui Liu, Yujian Lin, Ping Zhao, Jun Shi   +6 more
semanticscholar   +1 more source

A Biomedical Investigation of the Hepatoprotective Effect of Radix salviae miltiorrhizae and Network Pharmacology-Based Prediction of the Active Compounds and Molecular Targets [PDF]

, 2017
published_or_final_versio
Cheung, F, Feng, Y, HONG, M, LI, S, Tan, HY, Wang, N   +5 more
core   +4 more sources

Sodium Tanshinone IIA Sulfonate Attenuates Tumor Oxidative Stress and Promotes Apoptosis in an Intermittent Hypoxia Mouse Model

Technology in Cancer Research & Treatment, 2020
Objective: Intermittent hypoxia, a significant feature of obstructive sleep apnea, has pro-tumorigenic effects. Here, we investigated the effect of sodium tanshinone IIA sulfonate on oxidative stress and apoptosis in a mouse model of Lewis lung carcinoma
Xiao-Bin Zhang PhD, Xiao-Yang Chen PhD, Peng Sun MD, Xiao-Man Su Nurse, Hui-Qing Zeng PhD, Yi-Ming Zeng PhD, Miao Wang MD, Xiongbiao Luo PhD   +7 more
doaj   +1 more source

Tanshinone IIA effects on ovarian cancer cell line

Journal of Pharmacy and Pharmacology, 2018
Abstract Objectives To explore the potential therapeutic effect of Tanshinone IIA against ovarian cancer in vitro and elucidate the underlying molecular mechanism. Methods The cell survival upon Tanshinone IIA treatment was determined
Nan Li, Liang Yang, Baolian Zhang, Suqin Chen   +3 more
openaire   +2 more sources

Protection of lethal toxicity of endotoxin by Salvia miltiorrhiza BUNGE is via reduction in tumor necrosis factor alpha release and liver injury [PDF]

, 2006
Lipopolysaccharide (LPS) has been implicated as one of the major cause of Gram-negative bacteria-induced sepsis that are life-threatening syndromes occurring in intensive care unit patients. Many natural products derived from medicinal plants may contain
Chan, DKO, Fu, KHM, Lee, CL, Sit, WH, Wan, JMF   +4 more
core   +1 more source

Tanshinone IIA inhibits AGEs-induced proliferation and migration of cultured vascular smooth muscle cells by suppressing ERK1/2 MAPK signaling [PDF]

Iranian Journal of Basic Medical Sciences, 2018
Objective(s): Vascular smooth muscle cells (VSMCs) play a key role in the pathogenesis of diabetic vascular disease. Our current study sought to explore the effects of tanshinone IIA on the proliferation and migration of VSMCs induced by advanced ...
Ming Lu, Ying Luo, Pengfei Hu, Liping Dou, Shuwei Huang   +4 more
doaj   +1 more source

Cortical Organoid-on-a-Chip with Physiological Hypoxia for Investigating Tanshinone IIA-Induced Neural Differentiation

Research, 2023
Cortical organoids represent cutting-edge models for mimic human brain development during the early and even middle stage of pregnancy, while they often fail to recreate the complex microenvironmental factors, such as physiological hypoxia.
Yue Zhi, Yujuan Zhu, Jinglin Wang, Junqi Zhao, Yuanjin Zhao   +4 more
semanticscholar   +1 more source