Results 81 to 90 of about 8,021 (203)

Tanshinone IIA inhibits metastasis after palliative resection of hepatocellular carcinoma and prolongs survival in part via vascular normalization

Journal of Hematology & Oncology, 2012
Background Promotion of endothelial normalization restores tumor oxygenation and obstructs tumor cells invasion, intravasation, and metastasis. We therefore investigated whether a vasoactive drug, tanshinone IIA, could inhibit metastasis by inducing ...
Wang Wen-Quan, Liu Liang, Sun Hui-Chuan, Fu Yan-Ling, Xu Hua-Xiang, Chai Zong-Tao, Zhang Qiang-Bo, Kong Ling-Qun, Zhu Xiao-Dong, Lu Lu, Ren Zheng-Gang, Tang Zhao-You   +11 more
doaj   +1 more source

Traditional Chinese Medicine Modernization in Diagnosis and Treatment: Utilizing Artificial Intelligence and Nanotechnology

MedComm, Volume 7, Issue 2, February 2026.
Traditional Chinese medicine (TCM) faces great challenges during the development of modern medicine. Utilizing novel technologies such as artificial intelligence (AI) and nanotechnology facilitates TCM with great potential in precision diagnosis and improved treatments efficacy.
Wenqi Yu, Mengzhen Chen, Xueqi Tan, Xi Wei, Fan Sun, Hua Yan, Xue Xu, Hongcai Shang   +7 more
wiley   +1 more source

A Friendly Relationship between Endophytic Fungi and Medicinal Plants: A Systematic Review [PDF]

, 2016
Endophytic fungi or endophytes exist widely inside the healthy tissues of living plants, and are important components of plant micro-ecosystems. Over the long period of evolution, some co-existing endophytes and their host plants have established a ...
Abd_Allah, Ahmad, Amna, Bacon, Barazani, Bashyal, Behie, Bittleston, Bussaban, Camatti-Sartori, Cao, Cao, Carroll, Cavaglieri, Chakravarthi, Chen, Chen, Chen, Chen, Chen, Chen, Chen, Chithra, Chutima, Cui, D'Amico, Dai, Deng, Dingle, Duan, Eyberger, Faeth, Fan, Firáková, Gangadevi, Gangadevi, Gange, Gao, Gunatilaka, Guo, Guo, Guo, Gómez-Vidal, Harper, Hartley, Herrera-Carrillo, Huang, Huang, Jiang, Ju, Khan, Kim, Kour, Kozyrovska, Kumaran, Kumaran, Kusari, Kusari, Kusari, Kusari, Kusari, Kusari, Li, Li, Li, Li, Li, Li, Liu, Liu, Lu, Maciá-Vicente, Maehara, Meng, Ming, Mo, Moricca, Nascimento, Nejad, Osono, Pan, Puri, Puri, Qiu, Qiu, Redman, Rehman, Ren, Richardson, Rodrigues, Rodriguez, Rodriguez, Saikkonen, Saikkonen, Senthil Kumaran, Sherameti, Shrestha, Shwab, Shweta, Sieber, Silva, Song, Stierle, Stierle, Strobel, Strobel, Strobel, Sumarah, Sun, Sun, Suryanarayanan, Tan, Tang, Tofern, Torres, Unterseher, Venkatachalam, Wang, Wang, Wang, Wang, Wang, Wang, Waqas, Weyens, Wu, Yan, Yang, Yang, Yin, Yu, Zeng, Zhang, Zhang, Zhang, Zhang, Zhang, Zhang, Zhao, Zhao, Zhou, Zhou   +141 more
core   +1 more source

Tanshinone IIA Protects Against Cardiac Hypertrophy via Inhibiting Calcineurin/Nfatc3 Pathway

International Journal of Biological Sciences, 2011
Pathological cardiac hypertrophy induced by adrenergic overactivation can subsequently develop to heart failure which remains as a leading cause of mortality worldwide.
Xueying Tan, Jianping Li, Xinyue Wang, Nan Chen, Benzhi Cai, Gang Wang, Hongli Shan, Deli Dong, Yanju Liu, Xingda Li, Fan Yang, Xin Li, Peng Zhang, Xueqi Li, Baofeng Yang, Yanjie Lu
doaj  

Screening of Potential Thrombin and Factor Xa Inhibitors from the Danshen–Chuanxiong Herbal Pair through a Spectrum–Effect Relationship Analysis

Molecules, 2021
In this study; a spectrum–effect relationship analysis combined with a high-performance liquid chromatography–mass spectrometry (LC–MS) analysis was established to screen and identify active components that can inhibit thrombin and factor Xa (THR and FXa)
Xu Wang, Dai-Yan Zhang, Shi-Jun Yin, Hui Jiang, Min Lu, Feng-Qing Yang, Yuan-Jia Hu   +6 more
doaj   +1 more source

Adjunctive Therapies in Periodontitis: Current Concepts and the Future

Journal of Periodontal Research, Volume 61, Issue 2, Page 138-164, February 2026.
This graphical abstract summarizes the translational pathway from preclinical research to clinical implementation of adjunctive therapies for periodontitis, highlighting key barriers, innovative therapeutic strategies, and emerging tools that aim to bridge experimental discoveries with patient care.
Rafael Scaf de Molon, Joao Paulo Steffens, Erica Dorigatti de Avila, Wim Teughels, Thomas E. Van Dyke   +4 more
wiley   +1 more source

The Jasmonate‐Responsive SmMPK3–SmWRKY33 Module Positively Regulates Tanshinone Biosynthesis in Salvia miltiorrhiza

Plant Biotechnology Journal, Volume 24, Issue 2, Page 384-401, February 2026.
ABSTRACT Tanshinones, the major bioactive diterpenes in Salvia miltiorrhiza Bunge, are widely used to treat cardiovascular and cerebrovascular diseases. While jasmonates (JAs) are known to modulate tanshinones accumulation, the molecular link between JA signalling and tanshinone biosynthesis remains unclear.
Renjun Qu, Shiwei Wang, Xinxin Wang, Jiaming Peng, Juan Guo, Guanghong Cui, Tong Chen, Meilan Chen, Shuangshuang Zhao, Ye Shen   +9 more
wiley   +1 more source

Aldose Reductase Inhibitory Activity of Chinese Crude Drug "Danshen" [PDF]

, 2000
漢薬“丹参”の基源植物である丹参（Salvia miltiorhiza）及び中国新彊において丹参（S.miltiorhiza）の代用品として用いられている新彊丹参（S.deserta）のアルドース還元酵素阻害活性成分を調べたところ，両者の活性成分は全く異なっていた。さらに，丹参（S.miltiorhiza）の代用品として用いられている10種を含む17種類のSalvia属植物について，水およびメタノールエキスのアルドース還元酵素阻害活性およびLC-MS分析を比較した結果も ...
手塚 康弘, 門田 重利
core   +1 more source

Tanshinone IIA alters the transforming growth factor-1/Smads pathway in angiotensin II-treated rat hepatic stellate cells

Journal of International Medical Research, 2020
Objective To investigate the effects of tanshinone IIA on the transforming growth factor-β1 (TGF-β1)/Smads signaling pathway in angiotensin II-treated hepatic stellate cells (HSCs).
Guo-wei Wei, Ke-yue Li, Ke-li Tang, Cheng-Xian Shi   +3 more
doaj   +1 more source

Paeoniflorin Ameliorates Spinal Cord Injury by Controlling Apoptosis and Ferroptosis in H2O2‐Damaged PC12 Cells

Immunity, Inflammation and Disease, Volume 14, Issue 1, January 2026.
ABSTRACT Background Spinal cord injury (SCI) leads to severe neurological dysfunction. Current therapeutic strategies remain limited, with poor recovery rates. Oxidative stress and ferroptosis are key mechanisms underlying secondary SCI. Paeoniflorin has anti‐inflammatory, antioxidant, and neuroprotective properties; however, its role in regulating ...
Zongyu Zhang, Zhijing Zhou, Peng Zhang, Yongfeng Huo   +3 more
wiley   +1 more source