This review deals with the progress in the biosynthesis and regulation of tanshinones and salvianolic acids as well as the prospects and challenges for producing such compounds through biotechnology techniques.
Yingpeng Xu, Lijun Geng, Shujuan Zhao
doaj +1 more source
Molecular mechanism of tanshinone IIA and cryptotanshinone in platelet anti-aggregating effects: an integrated study of pharmacology and computational analysis. [PDF]
Tanshinone IIA and cryptotanshinone are two pharmacologically active diterpenoids extracted from the roots of Salvia milthiorriza Bunge, a plant used in Chinese traditional medicine for the treatment of some cardiovascular and cerebrovascular disease ...
Bifulco G. +5 more
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Recent insights into the biological activities and drug delivery systems of tanshinones
Yuee Cai,1,* Wenji Zhang,2,* Zirong Chen,3 Zhi Shi,1,2 Chengwei He,1 Meiwan Chen1 1State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macau, People’s Republic of China ...
Cai Y +5 more
doaj
A review study on medicinal plants affecting amnesia through cholinergic system [PDF]
Neurotransmitter modification is an important method for the treatment of memory loss or amnesia. Cholinomimetic drugs, particularly, acetylcholine esterase inhibitors are the mainstream in pharmacotherapy of amnesia. Donepezil, tacrine, galantamine, and
Baradaran, Azar. +3 more
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Synergistic Accumulative Effect of Salicylic Acid and Dibutyl Phthalate on Paclitaxel Production in Corylus avellana Cell Culture [PDF]
Suspension cell cultures of Corylus avellana were challenged with salicylic acid and its combined use with dibutyl phthalate solvent. Salicylic acid with concentrations of 12.5, 25 and 50 mg L–1 and 10% (v/v) dibutyl phthalate were used and added on day ...
Behmanesh, M. +4 more
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Danshen (Salvia miltiorrhiza) on the Global Market: What Are the Implications for Products' Quality? [PDF]
Background: Danshen (Radix et rhizoma Salviae miltiorrhizae; Salvia miltiorrhiza Bunge, Lamiaceae) is commonly used in Asia, including China, Japan, and Korea with markets in America and Europe growing substantially.
Heinrich, M +3 more
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Tanshinone IIA effects on ovarian cancer cell line
Abstract Objectives To explore the potential therapeutic effect of Tanshinone IIA against ovarian cancer in vitro and elucidate the underlying molecular mechanism. Methods The cell survival upon Tanshinone IIA treatment was determined
Nan Li +3 more
openaire +2 more sources
Trichoderma atroviride develops a symbiont relationship with Salvia miltiorrhiza and this association involves a number of signaling pathways and proteomic responses between both partners.
Wei Peng +7 more
doaj +1 more source
First evidence for an anxiolitic effect of a diterpenoid from Salvia cinnabarina
The potential anxiolytic and anti-depressive activity of CMP1 was studied in the elevated plus-maze test and in the forced swimming test. Furthermore, CMP1 sedative activity was evaluated in pentobarbital treated animals; the effect of CMP1 on ...
Bisio, A +8 more
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Herbal product's quality control using ¹H-NMR metabolomics approach – An example from Danshen (Salvia miltiorrhiza Bunge.) [PDF]
Radix Salviae miltiorrhizae is the only source of Danshen in pharmacopoeias. For thousands of years, it has been used in China for vascular and pain-related diseases.
Kum, Ka Yui
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