Results 91 to 100 of about 2,991 (214)

Bioavailability and pharmacokinetic comparison of tanshinones between two formulations of Salvia miltiorrhiza in healthy volunteers

Scientific Reports, 2017
Salvia miltiorrhiza (SM) is widely used to treat microcirculatory disturbance-related diseases; its lipophilic components play important roles in this application.
Lu Xing, Zhi-Rong Tan, Jin-Le Cheng, Wei-Hua Huang, Wei Zhang, Wen Deng, Chun-Su Yuan, Hong-Hao Zhou   +7 more
doaj   +1 more source

From Synthesis to Therapeutics: Bioactive‐Coated Zein Nanoparticles in Drug Delivery

Biopolymers, Volume 117, Issue 2, March 2026.
ABSTRACT Polymeric zein nanoparticles (ZNP), derived from corn protein, are biodegradable drug carriers with high stability and low synthesis costs. Their amphiphilic nature allows efficient encapsulation of both hydrophilic and lipophilic drugs, making them promising for drug delivery.
Milena Ferreira de Lima, Andy Joel Taipe Huisa, Azael da Silva Neto, Clarice Beatriz Gonçalves Silva, Iago Dillion Lima Cavalcanti, Karolliny Barbosa de Araújo, Mariane Cajubá de Britto Lira‐Nogueira, Nereide Stela Santos Magalhães, Priscila Gubert   +8 more
wiley   +1 more source

Optimization of Micellar Electrokinetic Chromatography Method for the Simultaneous Determination of Seven Hydrophilic and Four Lipophilic Bioactive Components in Three Salvia Species

Molecules, 2015
A micellar electrokinetic chromatography (MEKC) method was developed for the simultaneous determination of seven hydrophilic phenolic acids and four lipophilic tanshinones in three Salvia species.
Jiliang Cao, Ji Hu, Jinchao Wei, Baocai Li, Mi Zhang, Cheng Xiang, Peng Li   +6 more
doaj   +1 more source

Orthoquinone, Cyclic, and Acyclic α‐Diketone Natural Products: From Food Applications to Pharmacotherapy

Phytochemicals in Food and Medicine, Volume 1, Issue 1, March 2026.
The orthoquinone metabolites from plants have antimicrobial, antioxidant, antiviral, cytotoxic, and anti‐inflammatory effects. ABSTRACT The structural diversity of natural products is vast and fascinating, and they have been recognized as an enormously diverse source of new lead compounds.
Hidayat Hussain, Daijie Wang, Satyajit D. Sarker, Lutfun Nahar, Nilufar Z. Mamadalieva, Jianbo Xiao   +5 more
wiley   +1 more source

Overexpression of SmMYC2 Increases the Production of Phenolic Acids in Salvia miltiorrhiza

Frontiers in Plant Science, 2017
MYC2 is a core transcription factor in the plant response to jasmonates. It also functions in secondary metabolism and various processes for growth and development. However, the knowledge about its role in Salvia miltiorrhiza is still very limited.
Na Yang, Wenping Zhou, Jiao Su, Xiaofan Wang, Lin Li, Liru Wang, Xiaoyan Cao, Zhezhi Wang   +7 more
doaj   +1 more source

Enhancing Metabolic Engineering in Medicinal Plants Through Prime Editing

Plant Biotechnology Journal, Volume 24, Issue 5, Page 2858-2860, May 2026.
Haomiao Yu, Xiao Feng, Xiaohang Zheng, Xiao Wang, Wenxin Zheng, Zhizhou Zhang, Yuanyuan Jiang, Ruiwu Yang, Li Zhang, Zhaohui Zhong   +9 more
wiley   +1 more source

Viral Pathogens and Pulmonary Fibrosis: EMT‐Driven Mechanisms and Insights From Traditional Chinese Medicine

Reviews in Medical Virology, Volume 36, Issue 2, March 2026.
ABSTRACT Idiopathic pulmonary fibrosis (IPF) is a serious progressive complication of the respiratory system, which is profoundly associated with persistent extracellular matrix (ECM) deposition, fibrosis, and disrupted tissue regeneration. Emerging evidence shows that epithelial–mesenchymal transition (EMT) acts as a key factor in the pathogenesis of ...
Ningzi Zang, Yingxu Wu, Pin Li, Yongming Liu, Shiwen Wang, Jiapeng Leng, Libin Zhan, Xiaodong Lyu, Lijian Pang, Jiaran Wang   +9 more
wiley   +1 more source

Comparative efficacy of sweated and non-sweated Salvia miltiorrhiza Bge. extracts on acute myocardial ischemia via regulating the PPARα/RXRα/NF-κB signaling pathway

Heliyon
Salvia miltiorrhiza Bge. (S. miltiorrhiza) is a well-known traditional Chinese medicine for the treatment of cardiovascular diseases. The processing of S. miltiorrhiza requires the raw herbs to sweat first and then dry.
Xiaoxiao Shan, Junying Li, Bangzhen Hong, Huihui Yin, Ziyi Lu, Guokai Wang, Nianjun Yu, Daiyin Peng, Lei Wang, Caiyun Zhang, Weidong Chen   +10 more
doaj   +1 more source

Ag+ as a More Effective Elicitor for Production of Tanshinones than Phenolic Acids in Salvia miltiorrhiza Hairy Roots

Molecules, 2014
Phenolic acids and tanshinones are two groups of bioactive ingredients in Salvia miltiorrhiza Bunge. As a heavy metal elicitor, it has been reported that Ag+ can induce accumulations of both phenolic acids and tanshinones in S. miltiorrhiza hairy roots.
Bingcong Xing, Dongfeng Yang, Wanli Guo, Zongsuo Liang, Xijun Yan, Yonghong Zhu, Yan Liu   +6 more
doaj   +1 more source

Growth Inhibition of Tanshinones on SPC-A-1 Cell Line and their Structure-activity Relationship

Chinese Journal of Lung Cancer, 2011
Background and objective Numerous studies have shown that Tanshinones have anti-tumor effects in vitro, but few studies were focusing on the anti-tumor activity of Tanshinones against one special cancer cell line.
Huayue SHI, Qing ZHANG, Hui LI, Ting CHU, Hui JIN, Shengjun MAO   +5 more
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