Results 41 to 50 of about 2,942 (199)

Molecular Mechanism of Tanshinone against Prostate Cancer

Molecules, 2022
Prostate cancer (PCa) is the most common malignant tumor of the male urinary system in Europe and America. According to the data in the World Cancer Report 2020, the incidence rate of PCa ranks second in the prevalence of male malignant tumors and varies worldwide between regions and population groups.
Wei Li, Tao Huang, Shenghan Xu, Bangwei Che, Ying Yu, Wenjun Zhang, Kaifa Tang   +6 more
openaire   +3 more sources

Tissue-smashing based ultra-rapid extraction of chemical constituents in herbal medicines [PDF]

, 2014
postprin
Chen, C, Fan, Y, Li, P, Qi, LW, So, KF, Yan, CP   +5 more
core   +1 more source

The Anticancer Properties of Tanshinones and the Pharmacological Effects of Their Active Ingredients

Frontiers in Pharmacology, 2020
Cancer is a common malignant disease worldwide with an increasing mortality in recent years. Salvia miltiorrhiza, a well-known traditional Chinese medicine, has been used for the treatment of cardiovascular and cerebrovascular diseases for thousands of ...
Li Fu, Bing Han, Yang Zhou, Jie Ren, Wenzhi Cao, Gopal Patel, Guoyin Kai, Guoyin Kai, Jun Zhang   +8 more
doaj   +1 more source

Towards elucidating carnosic acid biosynthesis in Lamiaceae: Functional characterization of the three first steps of the pathway in Salvia fruticosa and Rosmarinus officinalis [PDF]

, 2015
Carnosic acid (CA) is a phenolic diterpene with anti-tumour, anti-diabetic, antibacterial and neuroprotective properties that is produced by a number of species from several genera of the Lamiaceae family, including Salvia fruticosa (Cretan sage) and ...
Božić, Dragana, Brückner, Kathleen, Chatzopoulou, Fani M., De Vos, Ric C.H., Dimitriadou, Eleni, Ferrer i Prats, Albert, Kampranis, Sotirios C., Kanellis, Angelos K., Katsarou, Dimitra, Kostas, Stefanos, Makris, Antonios M., Manzano Alías, David, Papaefthimiou, Dimitra, Papanikolaou, Antigoni, Pateraki, Irene, Scheler, Ulschan, Tissier, Alain, Tsoleridis, Constantinos A.   +17 more
core   +5 more sources

Simultaneous Determination of Four Tanshinones by UPLC-TQ/MS and Their Pharmacokinetic Application after Administration of Single Ethanol Extract of Danshen Combined with Water Extract in Normal and Adenine-Induced Chronic Renal Failure Rats

Molecules, 2016
Salvia miltiorrhiza, one of the major traditional Chinese medicines, is commonly used and the main active ingredients—tanshinones—possess the ability to improve renal function.
Hong-Die Cai, Shu-Lan Su, Yonghui Li, Zhenhua Zhu, Jianming Guo, Yue Zhu, Sheng Guo, Dawei Qian, Jinao Duan   +8 more
doaj   +1 more source

SmMYB4 Is a R2R3-MYB Transcriptional Repressor Regulating the Biosynthesis of Phenolic Acids and Tanshinones in Salvia miltiorrhiza

Metabolites, 2022
Salvia miltiorrhiza Bunge is one of the most famous traditional Chinese medicinal plants. The two most important classes of pharmaceutically relevant compounds in S. miltiorrhiza are phenolic acids and tanshinones. The MYB family of transcription factors
Qian Tian, Limin Han, Xiaoya Zhu, Caijuan Zhang, Yunyun Li, Xiaoshan Xue, Yueyue Wang, Donghao Wang, Junfeng Niu, Wenping Hua, Bin Li, Zhezhi Wang   +11 more
doaj   +1 more source

Molecular Mechanisms of Cardioprotective Actions of Tanshinones

Journal of Chemistry, 2016
Tanshinones are lipophilic compounds derived from Salvia miltiorrhiza (Danshen) that has been widely used to treat coronary heart diseases in China. The cardioprotective actions of tanshinones have been extensively studied in various models of myocardial
Hyou-Ju Jin, Chun-Guang Li
doaj   +1 more source

An overview of the anti-cancer actions of Tanshinones, derived from Salvia miltiorrhiza (Danshen)

Exploration of Targeted Anti-tumor Therapy, 2020
Tanshinone is a herbal medicinal compound described in Chinese medicine, extracted from the roots of Salvia miltiorrhiza (Danshen). This family of compounds, including Tanshinone IIA and Tanshinone I, have shown remarkable potential as anti-cancer ...
Irum Naz, Myriam Merarchi, Shanaya Ramchandani, Muhammad Rashid Khan, Muhammad Nouman Malik, Sumaira Sarwar, Acharan S Narula, Kwang Seok Ahn   +7 more
doaj   +1 more source

Flavoenzyme-mediated reduction reactions and antitumor activity of nitrogen-containing tetracyclic ortho-quinone compounds and their nitrated derivatives [PDF]

, 2017
Nitrogen-based tetracyclic ortho-quinones (naphtho[1'2':4.5]imidazo[1,2-a]pyridine-5,6-diones, NPDOs) and their nitro-substituted derivatives (nitro-(P)NPDOs) were obtained by condensation of substituted 2,3-dichloro- 1,4-naphthoquinones with 2-amino ...
Anusevičius, Žilvinas, Krikštopaitis, Kastis, Marozienė, Audronė, Misevičienė, Lina, Pečiukaitytė-Alksnė, Milda, Staniulytė, Zita, Čėnas, Narimantas, Šarlauskas, Jonas   +7 more
core   +1 more source

Enhancement of tanshinone production in Salvia miltiorrhiza hairy root cultures by metabolic engineering

Plant Methods, 2019
Background Tanshinones are diterpenoid compounds that are used to treat cardiovascular diseases. As current extraction methods for tanshinones are inefficient, there is a pressing need to improve the production of these bioactive compounds to meet ...
Tao Wei, Yonghong Gao, Kejun Deng, Lipeng Zhang, Meiling Yang, Xiaopei Liu, Caiyan Qi, Chunguo Wang, Wenqin Song, Yong Zhang, Chengbin Chen   +10 more
doaj   +1 more source