Results 41 to 50 of about 2,991 (214)

Functional characterization of the cytochrome P450 monooxygenase CYP71AU87 indicates a role in marrubiin biosynthesis in the medicinal plant Marrubium vulgare. [PDF]

open access: yes, 2019
BackgroundHorehound (Marrubium vulgare) is a medicinal plant whose signature bioactive compounds, marrubiin and related furanoid diterpenoid lactones, have potential applications for the treatment of cardiovascular diseases and type II diabetes.
Addison, J Bennett   +5 more
core   +6 more sources

Molecular Mechanism of Tanshinone against Prostate Cancer

open access: yesMolecules, 2022
Prostate cancer (PCa) is the most common malignant tumor of the male urinary system in Europe and America. According to the data in the World Cancer Report 2020, the incidence rate of PCa ranks second in the prevalence of male malignant tumors and varies worldwide between regions and population groups.
Wei Li   +6 more
openaire   +3 more sources

The Anticancer Properties of Tanshinones and the Pharmacological Effects of Their Active Ingredients

open access: yesFrontiers in Pharmacology, 2020
Cancer is a common malignant disease worldwide with an increasing mortality in recent years. Salvia miltiorrhiza, a well-known traditional Chinese medicine, has been used for the treatment of cardiovascular and cerebrovascular diseases for thousands of ...
Li Fu   +8 more
doaj   +1 more source

Simultaneous Determination of Four Tanshinones by UPLC-TQ/MS and Their Pharmacokinetic Application after Administration of Single Ethanol Extract of Danshen Combined with Water Extract in Normal and Adenine-Induced Chronic Renal Failure Rats

open access: yesMolecules, 2016
Salvia miltiorrhiza, one of the major traditional Chinese medicines, is commonly used and the main active ingredients—tanshinones—possess the ability to improve renal function.
Hong-Die Cai   +8 more
doaj   +1 more source

An overview of the anti-cancer actions of Tanshinones, derived from Salvia miltiorrhiza (Danshen)

open access: yesExploration of Targeted Anti-tumor Therapy, 2020
Tanshinone is a herbal medicinal compound described in Chinese medicine, extracted from the roots of Salvia miltiorrhiza (Danshen). This family of compounds, including Tanshinone IIA and Tanshinone I, have shown remarkable potential as anti-cancer ...
Irum Naz   +7 more
doaj   +1 more source

SmMYB4 Is a R2R3-MYB Transcriptional Repressor Regulating the Biosynthesis of Phenolic Acids and Tanshinones in Salvia miltiorrhiza

open access: yesMetabolites, 2022
Salvia miltiorrhiza Bunge is one of the most famous traditional Chinese medicinal plants. The two most important classes of pharmaceutically relevant compounds in S. miltiorrhiza are phenolic acids and tanshinones. The MYB family of transcription factors
Qian Tian   +11 more
doaj   +1 more source

Enhancement of tanshinone production in Salvia miltiorrhiza hairy root cultures by metabolic engineering

open access: yesPlant Methods, 2019
Background Tanshinones are diterpenoid compounds that are used to treat cardiovascular diseases. As current extraction methods for tanshinones are inefficient, there is a pressing need to improve the production of these bioactive compounds to meet ...
Tao Wei   +10 more
doaj   +1 more source

Tanshinone Inhibits NSCLC by Downregulating AURKA Through Let-7a-5p

open access: yesFrontiers in Genetics, 2020
Lung cancer is the most deadly malignancy in the last decade, accounting for about 1.6 million deaths every year globally. Tanshinone is the constituent of Salvia miltiorrhiza; it has been found that they influence tumorigenesis.
Xiaomin Liu   +8 more
doaj   +1 more source

Effects of Native Arbuscular Mycorrhizae Isolated on Root Biomass and Secondary Metabolites of Salvia miltiorrhiza Bge

open access: yesFrontiers in Plant Science, 2021
Arbuscular mycorrhiza fungi (AMFs) are a group of soil-dwelling fungi that form symbiotic associations with plants, to mediate the secondary metabolism and production of active ingredients in aromatic and medicinal plants.
Yan-Hong Wu   +6 more
doaj   +1 more source

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